Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study
NCT04739072 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2025-11-13
Summary
This study investigates if circulating tumor DNA (ctDNA) and other tumor-related molecules/chemicals released in the blood can help doctors predict if colorectal cancer may come back or spread. Tumors shed DNA and other cancer related chemicals into the blood that can be identified and studied further to provide information about the cancer. Information gathered from this study may help researchers better understand if ctDNA found in the blood can predict whether colorectal cancer may come back or spread.
Conditions
- Colorectal Adenocarcinoma
- Stage I Colorectal Cancer AJCC v8
- Stage II Colorectal Cancer AJCC v8
- Stage IIA Colorectal Cancer AJCC v8
- Stage IIB Colorectal Cancer AJCC v8
- Stage IIC Colorectal Cancer AJCC v8
- Stage III Colorectal Cancer AJCC v8
- Stage IIIA Colorectal Cancer AJCC v8
- Stage IIIB Colorectal Cancer AJCC v8
- Stage IIIC Colorectal Cancer AJCC v8
- Stage IV Colorectal Cancer AJCC v6
- Stage IVA Colorectal Cancer AJCC v8
- Stage IVB Colorectal Cancer AJCC v8
- Stage IVC Colorectal Cancer AJCC v8
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of blood and tissue samples
- OTHER
-
Electronic Health Record Review
Review of medical records
Sponsors & Collaborators
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Arvind Dasari · M.D. Anderson Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-11-22
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- United States
Study Locations
More Related Trials
-
Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
NCT03789162 ·Status: COMPLETED
-
Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction
NCT06096688 ·Status: RECRUITING
-
Cohort Study to Evaluate the Relapse Risk Test in Colorectal Cancer
NCT05115786 ·Status: UNKNOWN
-
Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Treatment of Colorectal Cancer
NCT00005640 ·Status: COMPLETED ·Phase: NA
-
A Study of Imaging, Blood, and Tissue Samples to Guide Treatment of Colon Cancer and Related Liver Tumors
NCT03432806 ·Status: ACTIVE_NOT_RECRUITING
-
Predicting Disease Progression and/or Recurrence in Cancer
NCT04776837 ·Status: COMPLETED
-
Point of Care Test to Diagnosed Colorectal Cancer and Polyps in Low Middle Income Countries
NCT03173729 ·Status: COMPLETED
-
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
NCT05463796 ·Status: RECRUITING
-
Peripheral Blood DNA Methylation Markers for the Early Detection of Colorectal Carcinoma in the Egyptian Population
NCT01793207 ·Status: COMPLETED
-
The Detection of Circulating Tumor Cells (CTCs) in Patients With Colorectal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
NCT02450422 ·Status: COMPLETED
-
Presence of Circulating Tumor DNA in Colorectal Cancer
NCT01198743 ·Status: COMPLETED
-
Application of FIT-DNA Detection in Following Colorectal Cancer Resection-Implications for Surveillance
NCT05528783 ·Status: RECRUITING
-
Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients
NCT00582829 ·Status: COMPLETED
-
Collection of Blood, Urine, and Stool to Monitor MetastaticColorectal Cancers
NCT03563651 ·Status: COMPLETED
-
Young-Onset Colorectal Cancer
NCT02863107 ·Status: ACTIVE_NOT_RECRUITING
-
Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients
NCT00899626 ·Status: RECRUITING
-
Impact of Family History and Decision Support on High-risk Cancer Screening
NCT02247336 ·Status: COMPLETED ·Phase: NA
-
Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants
NCT00617071 ·Status: UNKNOWN ·Phase: PHASE3
-
Treatment Response Prediction System of mCRC Patients Based on CTC
NCT04917276 ·Status: NOT_YET_RECRUITING
-
Point of Care, Real-Time Urine Metabolomics Test to Diagnose Colorectal Cancers and Polyps in Low-and Middle-Income Countries
NCT05679960 ·Status: SUSPENDED ·Phase: NA
-
Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma
NCT05636085 ·Status: NOT_YET_RECRUITING
-
Quantifying Micro RNA Levels of Colon
NCT01712958 ·Status: UNKNOWN
-
Validation of Advanced Colorectal Neoplasm Risk Categories in a Prospective Cohort in Mexico
NCT05661292 ·Status: UNKNOWN
-
Personal Electronic Health Records in Improving Screening Rates for Colorectal Cancer
NCT01032746 ·Status: UNKNOWN ·Phase: NA
-
Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy
NCT01934179 ·Status: TERMINATED