Clinical Trials

NCT04132999 | COMPLETED | NA

27 participants

Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-03-01

Completion:

2025-09-30

Conditions

• Down Syndrome
• Obstructive Sleep Apnea

Interventions

• BEHAVIORAL

No Results Yet

NCT04130997 | ACTIVE_NOT_RECRUITING | PHASE3

1100 participants

An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-11-18

Completion:

2032-05-31

Conditions

• Relapsing Multiple Sclerosis (RMS)

Interventions

• BIOLOGICAL

No Results Yet

NCT04124380 | COMPLETED | NA

82 participants

Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-06-02

Completion:

2026-04-15

Conditions

• Alcohol; Use, Problem
• Posttraumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04097145 | RECRUITING | NA

1270 participants

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-12-11

Completion:

2027-12-31

Conditions

• Tricuspid Regurgitation
• Tricuspid Valve Insufficiency
• Tricuspid Valve Disease

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04092283 | ACTIVE_NOT_RECRUITING | PHASE3

660 participants

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2020-04-29

Completion:

2028-12-31

Conditions

• Recurrent Lung Non-Small Cell Carcinoma
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Unresectable Lung Non-Small Cell Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04077723 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

498 participants

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-08-13

Completion:

2027-03-31

Conditions

• Lymphoma, Non-Hodgkin

Interventions

• DRUG

No Results Yet

NCT04018391 | COMPLETED | NA

280 participants

Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-07-12

Completion:

2024-05-31

Conditions

• HIV Infections
• Depression

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04016818 | WITHDRAWN | EARLY_PHASE1

0 participants

Pilot Breast-Dedicated PET Camera With 1 Millimeter Spatial Resolution

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2026-06-30

Completion:

2027-12-31

Conditions

• Breast Cancer

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04014348 | RECRUITING

250 participants

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-10-20

Completion:

2026-12-10

Conditions

• Cardiovascular (CV) Risk

No Results Yet

NCT04002505 | ENROLLING_BY_INVITATION | NA

370 participants

The "Concussion or Brain Bleed" Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-06-27

Completion:

2030-12-31

Conditions

• Head Injury

Interventions

• OTHER

No Results Yet

NCT03984448 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

363 participants

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-10-22

Completion:

2028-04-01

Conditions

• Diffuse Large B-Cell Lymphoma
• Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• Double-Expressor Lymphoma
• EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
• High Grade B-Cell Lymphoma, Not Otherwise Specified
• Neoplastic Cells With Double Expression of MYC and BCL2 Proteins Present
• Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03952624 | RECRUITING

692 participants

Patient-Centered Assessment of Symptoms and Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-09-13

Completion:

2026-06-01

Conditions

• Fatigue
• Cancer
• CFS
• ME/CFS
• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
• Lupus
• Systemic Lupus Erthematosus
• Sjogrens

No Results Yet

NCT03952598 | SUSPENDED | PHASE2

42 participants

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-10-16

Completion:

2027-12-31

Conditions

• Glioma
• Gliomas
• High Grade Glioma
• Malignant Glioma
• Low Grade Glioma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT03941171 | COMPLETED | NA

69 participants

Is Periacetabular Osteotomy Superior to Progressive Resistance Training?

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-07-01

Completion:

2025-09-15

Conditions

• Hip Dysplasia

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT03922724 | RECRUITING | PHASE2

330 participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-04-18

Completion:

2026-10-31

Conditions

• Peripheral T-cell Lymphomas
• Lymphoproliferative Disorders
• Immune System Diseases

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03910465 | RECRUITING

300 participants

Children and Adults With Chordoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-04-16

Completion:

2029-12-31

Conditions

• Chordoma

No Results Yet

NCT03901287 | COMPLETED | NA

60 participants

Quantitative Dual Energy Computed Tomography in Pulmonary Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-08-02

Completion:

2021-01-15

Conditions

• Pulmonary Hypertension

Interventions

• OTHER

No Results Yet

NCT03899402 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

78 participants

Triple Therapy in T1DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-05-01

Completion:

2026-01-31

Conditions

• Type 1 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT03890614 | ACTIVE_NOT_RECRUITING

70 participants

Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-05-16

Completion:

2027-02-28

Conditions

• Hematologic Malignancy

Interventions

• OTHER

No Results Yet

NCT03866382 | RECRUITING | PHASE2

314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-05-13

Completion:

2027-02-28

Conditions

• Bladder Adenocarcinoma
• Bladder Clear Cell Adenocarcinoma
• Bladder Mixed Adenocarcinoma
• Bladder Neuroendocrine Carcinoma
• Bladder Small Cell Neuroendocrine Carcinoma
• Bladder Squamous Cell Carcinoma
• Chromophobe Renal Cell Carcinoma
• Collecting Duct Carcinoma
• Invasive Bladder Giant Cell Urothelial Carcinoma
• Invasive Bladder Lymphoepithelioma-Like Carcinoma
• Invasive Bladder Nested Urothelial Carcinoma
• Invasive Bladder Plasmacytoid Urothelial Carcinoma
• Invasive Bladder Sarcomatoid Urothelial Carcinoma
• Invasive Bladder Urothelial Carcinoma
• Kidney Medullary Carcinoma
• Large Cell Neuroendocrine Carcinoma
• Malignant Testicular Leydig Cell Tumor
• Malignant Testicular Sertoli Cell Tumor
• Metastatic Bladder Carcinoma
• Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
• Metastatic Bladder Giant Cell Urothelial Carcinoma
• Metastatic Bladder Large Cell Neuroendocrine Carcinoma
• Metastatic Bladder Lipid-Rich Urothelial Carcinoma
• Metastatic Bladder Micropapillary Urothelial Carcinoma
• Metastatic Bladder Plasmacytoid Urothelial Carcinoma
• Metastatic Bladder Sarcomatoid Urothelial Carcinoma
• Metastatic Bladder Small Cell Neuroendocrine Carcinoma
• Metastatic Bladder Squamous Cell Carcinoma
• Metastatic Chromophobe Renal Cell Carcinoma
• Metastatic Kidney Medullary Carcinoma
• Metastatic Malignant Genitourinary System Neoplasm
• Metastatic Papillary Renal Cell Carcinoma
• Metastatic Penile Carcinoma
• Metastatic Prostate Small Cell Neuroendocrine Carcinoma
• Metastatic Sarcomatoid Renal Cell Carcinoma
• Metastatic Urethral Carcinoma
• Papillary Renal Cell Carcinoma
• Sarcomatoid Renal Cell Carcinoma
• Stage IV Bladder Cancer AJCC v8
• Stage IV Penile Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IV Urethral Cancer AJCC v8
• Stage IVB Prostate Cancer AJCC v8
• Urachal Adenocarcinoma
• Urethral Clear Cell Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03855787 | COMPLETED | NA

103 participants

Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-11-11

Completion:

2025-09-26

Conditions

• Kidney Calculi

Interventions

• PROCEDURE

No Results Yet

NCT03842228 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-11-21

Completion:

2024-07-29

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT03827343 | ACTIVE_NOT_RECRUITING

500 participants

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-01-23

Completion:

2026-12-31

Conditions

• Macrophage Activation Syndrome
• Primary Hemophagocytic Lymphohistiocytosis

No Results Yet

NCT03811015 | ACTIVE_NOT_RECRUITING | PHASE3

636 participants

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-08-16

Completion:

2027-01-01

Conditions

• Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER
• RADIATION
• BIOLOGICAL

No Results Yet

NCT03805607 | COMPLETED | PHASE4

40 participants

IV Ketorolac on Platelet Function Post-Cesarean Delivery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-01-18

Completion:

2022-02-03

Conditions

• Analgesia, Obstetrical
• Coagulation Defect; Postpartum
• Nonsteroidals (NSAIDs)Toxicity
• Postpartum Hemorrhage
• Postoperative Pain
• Ketorolac Adverse Reaction
• Blood Loss, Postoperative

Interventions

• DRUG

Results Available

NCT03793179 | ACTIVE_NOT_RECRUITING | PHASE3

600 participants

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-04-05

Completion:

2027-09-30

Conditions

• Lung Non-Squamous Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03793166 | ACTIVE_NOT_RECRUITING | PHASE3

1175 participants

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-06-07

Completion:

2028-01-25

Conditions

• Clear Cell Renal Cell Carcinoma
• Metastatic Malignant Neoplasm in the Bone
• Metastatic Malignant Neoplasm in the Lymph Nodes
• Metastatic Malignant Neoplasm in the Soft Tissue
• Metastatic Malignant Neoplasm in the Viscera
• Rhabdoid Tumor of the Kidney
• Sarcomatoid Renal Cell Carcinoma
• Stage III Renal Cell Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT03790943 | RECRUITING

500 participants

Cardiac Dysfunction in Childhood Cancer Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2018-02-13

Completion:

2029-04-23

Conditions

• Cardiac Dysfunction
• Cardiovascular Diseases
• Childhood Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03775265 | ACTIVE_NOT_RECRUITING | PHASE3

475 participants

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-06-03

Completion:

2027-06-01

Conditions

• Bladder Urothelial Carcinoma
• Muscle Invasive Bladder Carcinoma
• Stage II Bladder Cancer AJCC v8
• Stage IIIA Bladder Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT03774914 | COMPLETED

42 participants

LEMTRADA Pregnancy Registry in Multiple Sclerosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2015-09-01

Completion:

2021-11-22

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT03762733 | ENROLLING_BY_INVITATION

500 participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-04

Completion:

2028-12-29

Conditions

• Breast Cancer
• Ovarian Cancer
• Uterine Cancer

No Results Yet

NCT03754335 | COMPLETED | NA

74 participants

SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2018-11-28

Completion:

2022-12-01

Conditions

• Aneurysmal Subarachnoid Hemorrhage
• Headache

Interventions

• PROCEDURE

No Results Yet

NCT03745339 | RECRUITING

150 participants

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-06-07

Completion:

2026-10-01

Conditions

• Opioid-Related Disorders
• Drug Addiction

No Results Yet

NCT03740204 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

The Role of Estrogen in the Neurobiology of Eating Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-06-13

Completion:

2025-12-30

Conditions

• Eating Disorders
• Hypoestrogenemia

Interventions

• DRUG

No Results Yet

NCT03739814 | RECRUITING | PHASE2

84 participants

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-05-08

Completion:

2027-02-01

Conditions

• B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
• Recurrent B Acute Lymphoblastic Leukemia
• Refractory B Acute Lymphoblastic Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT03737981 | ACTIVE_NOT_RECRUITING | PHASE3

465 participants

Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-01-31

Completion:

2025-01-17

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

Results Available

NCT03736226 | ACTIVE_NOT_RECRUITING

2000 participants

A Post-Approval, Single-Arm Study of the SYNERGY Stent System in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-07-30

Completion:

2024-08-01

Conditions

• Cardiovascular Diseases

Interventions

• DEVICE

No Results Yet

NCT03701282 | ACTIVE_NOT_RECRUITING | PHASE3

720 participants

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-02-12

Completion:

2028-05-07

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT03697577 | ACTIVE_NOT_RECRUITING

30 participants

CDK and Body Composition Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-01-08

Completion:

2026-08-31

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03693170 | COMPLETED | PHASE2

95 participants

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2019-01-17

Completion:

2020-06-29

Conditions

• BRAF V600E-mutant Metastatic Colorectal Cancer

Interventions

• DRUG

Results Available