Is Periacetabular Osteotomy Superior to Progressive Resistance Training?

Summary

The primary aim of this study is to examine if Periacetabular Osteotomy (PAO) followed by 4 months of usual care followed by 8 months of progressive resistance training (PRT) is superior to 12 months of a PRT intervention in patients with hip dysplasia eligible for PAO in terms of self-reported pain on the HAGOS questionnaire. Secondary aims are to investigate changes in patient-reported symptoms, physical function in daily living, physical function in sport and recreation, hip and/or groin-related quality of life, generic health status, functional performance, muscle strength, physical activity and adverse events between PAO followed by usual care+PRT compared to PRT only. We hypothesise that in patients with hip dysplasia, PAO followed by usual care+PRT, results in significantly less pain at 12 months follow-up, compared to PRT only.

Conditions

• Hip Dysplasia

Interventions

PROCEDURE

PAO

PAO will be performed as the trans-sartorial approach or the anterior pelvic approach.

OTHER

Usual care after PAO

Patients commence post-operative rehabilitation as usual and follow the rehabilitation program guided by a physiotherapist specialized in hip problems until 4 months after the operation.

OTHER

PRT

4 months of partly supervised progressive resistance training 2 times per week. After these 4 months (16 weeks), patients receive a free membership to a fitness center near their home address and are encouraged to train on their own 2 times per week until 12 months follow-up with one supervised session per month. The PRT program involves 10-min of warm up followed by 50-min of bilateral resistance exercises including sets of squats, hip extension, hip flexion, and hip abduction.

Sponsors & Collaborators

• Aarhus University Hospital

  collaborator OTHER

• VIA University College

  collaborator OTHER

• University of Aarhus

  lead OTHER

Principal Investigators

• Lisa U Tønning, MSc · Department of Orthopedic Surgery, Aarhus University Hospital, Denmark

• Inger Mechlenburg, DMSc, PhD · Department of Clinical Medicine, Aarhus University, Denmark

• Ulrik Dalgas, MSc, PhD · Department of Public Health - Sport, Aarhus University, Denmark

• Stig S Jakobsen, PhD · Department of Orthopedic Surgery, Aarhus University Hospital, Denmark

• Kjeld Søballe, DMSc · Department of Orthopedic Surgery, Aarhus University Hospital, Denmark

• Julie S Jacobsen, MSc · Department of Physiotherapy & Research Centre in Health and Welfare Technology, VIA University College, Denmark

• Jan E Madsen, MD, PhD · Department of Orthopedic Surgery, Oslo University Hospital, Norway

• Lars Nordsletten, PhD · Division of Orthopaedic Surgery, Oslo University Hospital, Oslo; Faculty of Medicine, University of Oslo, Norway

• Tone Bere, PT, PhD · Department of Orthopedics, Oslo University Hospital Ullevaal, Norway

• May A Risberg, PhD · Department of Orthopedics, Oslo University Hospital Ullevaal, Norway

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2019-07-01

Primary Completion

2025-09-15

Completion

2025-09-15

Countries

• Denmark
• Norway

Study Locations