Clinical Trials

NCT03199885 | TERMINATED | PHASE3

190 participants

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2019-04-05
Completion:: 2024-04-30

Conditions

Metastatic Breast Adenocarcinoma
Metastatic HER2-Positive Breast Carcinoma
Recurrent Breast Adenocarcinoma
Recurrent HER2-Positive Breast Carcinoma
Stage III Breast Cancer AJCC v7
Stage IV Breast Cancer AJCC v6 and v7
Unresectable Breast Carcinoma
Unresectable HER2-Positive Breast Carcinoma

Interventions

DRUG
PROCEDURE
BIOLOGICAL
OTHER

Results Available

NCT03190941 | RECRUITING | PHASE1/PHASE2

110 participants

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-09-21
Completion:: 2027-06-29

Conditions

Pancreatic Cancer
Gastric Cancer
Gastrointestinal Cancer
Colon Cancer
Rectal Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT03186898 | ACTIVE_NOT_RECRUITING | PHASE3

186 participants

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2018-01-26
Completion:: 2026-01-20

Conditions

Recurrent Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v7
Unresectable Hepatocellular Carcinoma

Interventions

PROCEDURE
OTHER
RADIATION

No Results Yet

NCT03173924 | ACTIVE_NOT_RECRUITING | PHASE2

96 participants

18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-06-06
Completion:: 2028-02-06

Conditions

Metastatic Prostate Cancer
Prostatic Neoplasms
Prostate Cancer
Prostatic Cancer
Prostate Neoplasms

Interventions

DRUG

No Results Yet

NCT03161808 | RECRUITING

500 participants

Rare CFTR Mutation Cell Collection Protocol (RARE)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-10-05
Completion:: 2027-12-01

Conditions

Cystic Fibrosis

No Results Yet

NCT03157323 | ACTIVE_NOT_RECRUITING | NA

88 participants

Low GI Diet in Children and Adolescents With ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-06-01
Completion:: 2023-06-01

Conditions

Acute Lymphoblastic Leukemia, Pediatric
Obesity, Pediatric

Interventions

BEHAVIORAL

No Results Yet

NCT03128996 | RECRUITING | PHASE1/PHASE2

29 participants

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-03-20
Completion:: 2028-04-30

Conditions

Severe Sickle Cell Disease
Bone Marrow Failure Syndromes
Metabolic Disorders
Immunologic Disorders
Hemoglobinopathies
Non-malignant Disorders

Interventions

DRUG

No Results Yet

NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2

56 participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-04-19
Completion:: 2026-06-30

Conditions

Thymoma
Thymic Carcinoma

Interventions

DRUG

No Results Yet

NCT03055013 | ACTIVE_NOT_RECRUITING | PHASE3

819 participants

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-04-28
Completion:: 2023-05-24

Conditions

Metastatic Renal Cell Carcinoma
Sarcomatoid Renal Cell Carcinoma
Stage II Renal Cell Cancer AJCC v7
Stage III Renal Cell Cancer AJCC v7
Unclassified Renal Cell Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
OTHER

Results Available

NCT03053791 | RECRUITING | NA

5 participants

Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2018-03-15
Completion:: 2026-12-31

Conditions

Spinal Cord Injury

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT03036930 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-06-23
Completion:: 2024-03-04

Conditions

Human Papillomavirus Infection
Human Papillomavirus-Related Carcinoma

Interventions

PROCEDURE
OTHER
BIOLOGICAL

Results Available

NCT03030404 | COMPLETED

733 participants

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-01-27
Completion:: 2025-03-31

Conditions

Stomach Neoplasms
Stomach Cancer
Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)
Hereditary Diffuse Gastric Cancer (HDGC)
Familial Diffuse Gastric Cancer

No Results Yet

NCT03027440 | ACTIVE_NOT_RECRUITING

52966 participants

The Developmental Origins of Suicide Mortality

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-01-10
Completion:: 2026-07-13

Conditions

Suicide Mortality

No Results Yet

NCT03027310 | COMPLETED

85 participants

Clinical and Physiological Studies of Tremor Syndromes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-05-05
Completion:: 2022-03-23

Conditions

Parkinson Disease
Dystonia
Essential Tremor

No Results Yet

NCT02984124 | COMPLETED | PHASE2/PHASE3

182 participants

Communication During Hospitalization About Resuscitation Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-12-31
Completion:: 2023-03-31

Conditions

Severe Life-limiting COPD
Severe Life-limiting Heart Failure
Severe Life-limiting Cirrhosis
Severe Life-limiting Malignancy
Severe Functional Impairment
End Stage Renal Disease

Interventions

BEHAVIORAL

No Results Yet

NCT02971501 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2018-06-27
Completion:: 2025-02-18

Conditions

Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
Stage IV Lung Cancer AJCC v8

Interventions

BIOLOGICAL
PROCEDURE
DRUG

Results Available

NCT02968810 | ACTIVE_NOT_RECRUITING | PHASE2

52 participants

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-06-21
Completion:: 2023-05-03

Conditions

Cirrhosis
Hepatocellular Carcinoma

Interventions

PROCEDURE
OTHER
DRUG

Results Available

NCT02954874 | ACTIVE_NOT_RECRUITING | PHASE3

1155 participants

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-01-18
Completion:: 2027-05-31

Conditions

Breast Carcinoma In Situ
Invasive Breast Carcinoma
Stage I Breast Cancer AJCC v7
Stage II Breast Cancer AJCC v6 and v7
Stage III Breast Cancer AJCC v7
Triple-Negative Breast Carcinoma

Interventions

PROCEDURE
OTHER
BIOLOGICAL
RADIATION

No Results Yet

NCT02901665 | COMPLETED | NA

191 participants

Impact of Increased Parent Presence in the Neonatal Intensive Care Unit on Parent & Infant Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2014-09-01
Completion:: 2018-09-30

Conditions

Family Relationship
Stress
Breastfeeding
Bottle Feeding
Complications

Interventions

OTHER

Results Available

NCT02890797 | TERMINATED | NA

19 participants

Assessment of Thoracic Echography for Pleuroparenchymatous Anomaly Diagnosis Complicating Bronchiolitis: BronchioIUS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2018-07-12
Completion:: 2020-02-10

Conditions

Bronchiolitis

Interventions

RADIATION

No Results Yet

NCT02890160 | COMPLETED | NA

430 participants

A Trial of Firesorb in Patients With Coronary Artery Disease: FUTURE-II

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-08-24
Completion:: 2020-10-31

Conditions

Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT02879695 | ACTIVE_NOT_RECRUITING | PHASE1

28 participants

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-10-25
Completion:: 2023-05-22

Conditions

Recurrent B Acute Lymphoblastic Leukemia
Recurrent Mixed Phenotype Acute Leukemia
Refractory B Acute Lymphoblastic Leukemia
Refractory Mixed Phenotype Acute Leukemia

Interventions

PROCEDURE
BIOLOGICAL

Results Available

NCT02858336 | COMPLETED | NA

38 participants

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-01-12
Completion:: 2019-06-29

Conditions

Hormones

Interventions

BEHAVIORAL

No Results Yet

NCT02834013 | ACTIVE_NOT_RECRUITING | PHASE2

818 participants

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2017-01-30
Completion:: 2027-05-01

Conditions

Acinar Cell Carcinoma
Adenoid Cystic Carcinoma
Adrenal Cortical Carcinoma
Adrenal Gland Pheochromocytoma
Anal Canal Neuroendocrine Carcinoma
Anal Canal Undifferentiated Carcinoma
Angiosarcoma
Apocrine Neoplasm
Appendix Mucinous Adenocarcinoma
Bartholin Gland Transitional Cell Carcinoma
Basal Cell Carcinoma
Bladder Adenocarcinoma
Breast Metaplastic Carcinoma
Cervical Adenocarcinoma
Cholangiocarcinoma
Chordoma
Colorectal Squamous Cell Carcinoma
Desmoid Fibromatosis
Endometrial Transitional Cell Carcinoma
Endometrioid Adenocarcinoma
Esophageal Neuroendocrine Carcinoma
Esophageal Undifferentiated Carcinoma
Extrahepatic Bile Duct Carcinoma
Extramammary Paget Disease
Fallopian Tube Adenocarcinoma
Fallopian Tube Transitional Cell Carcinoma
Fibromyxoid Tumor
Gallbladder Carcinoma
Gastric Neuroendocrine Carcinoma
Gastric Squamous Cell Carcinoma
Gastric Undifferentiated Carcinoma
Gastrointestinal Stromal Tumor
Gestational Trophoblastic Tumor
Giant Cell Carcinoma
Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type
Intestinal Neuroendocrine Carcinoma
Intrahepatic Cholangiocarcinoma
Lung Neuroendocrine Tumor
Lung Sarcomatoid Carcinoma
Major Salivary Gland Carcinoma
Malignant Neoplasm of Unknown Primary
Malignant Odontogenic Neoplasm
Malignant Peripheral Nerve Sheath Tumor
Malignant Solid Neoplasm
Malignant Testicular Sex Cord-Stromal Tumor
Metastatic Pituitary Neuroendocrine Tumor
Minimally Invasive Lung Adenocarcinoma
Mixed Mesodermal (Mullerian) Tumor
Mucinous Adenocarcinoma
Mucinous Cystadenocarcinoma
Nasal Cavity Adenocarcinoma
Nasal Cavity Carcinoma
Nasopharyngeal Carcinoma
Nasopharyngeal Low Grade Papillary Adenocarcinoma
Nasopharyngeal Undifferentiated Carcinoma
Oral Cavity Carcinoma
Oropharyngeal Undifferentiated Carcinoma
Ovarian Adenocarcinoma
Ovarian Germ Cell Tumor
Ovarian Mucinous Adenocarcinoma
Ovarian Squamous Cell Carcinoma
Ovarian Transitional Cell Carcinoma
Pancreatic Acinar Cell Carcinoma
Pancreatic Neuroendocrine Carcinoma
Paraganglioma
Paranasal Sinus Adenocarcinoma
Paranasal Sinus Carcinoma
Parathyroid Gland Carcinoma
PEComa
Penile Squamous Cell Carcinoma
Peritoneal Mesothelial Neoplasm
Placental Choriocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Pseudomyxoma Peritonei
Rare Disorder
Scrotal Squamous Cell Carcinoma
Seminal Vesicle Adenocarcinoma
Seminoma
Serous Cystadenocarcinoma
Small Intestinal Adenocarcinoma
Small Intestinal Squamous Cell Carcinoma
Spindle Cell Neoplasm
Teratoma With Somatic-Type Malignancy
Testicular Non-Seminomatous Germ Cell Tumor
Thyroid Gland Carcinoma
Tracheal Carcinoma
Transitional Cell Carcinoma
Ureter Adenocarcinoma
Ureter Squamous Cell Carcinoma
Urethral Adenocarcinoma
Urethral Squamous Cell Carcinoma
Vaginal Adenocarcinoma
Vaginal Squamous Cell Carcinoma, Not Otherwise Specified
Vulvar Carcinoma

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT02821767 | RECRUITING

1000 participants

Natural History, Pathogenesis, and Outcome of Ocular Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-08-03
Completion:: 2026-07-01

Conditions

Eye Disease

No Results Yet

NCT02757859 | ACTIVE_NOT_RECRUITING | NA

845 participants

WASH Trial: Intraoperative Lavage as a Treatment for Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-04-27
Completion:: 2028-08-31

Conditions

Acinar Cell Carcinoma
Ampulla of Vater Adenocarcinoma
Cholangiocarcinoma
Duodenal Adenocarcinoma
Pancreatic Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Pancreatic Intraductal Papillary Mucinous Neoplasm
Periampullary Adenocarcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT02741440 | RECRUITING

25 participants

Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-07-11
Completion:: 2028-12-31

Conditions

Spinocerebellar Ataxia

No Results Yet

NCT02710916 | COMPLETED | NA

109 participants

SD-OCT Multimodal Analysis in GLaucoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-02-22
Completion:: 2018-12-21

Conditions

Glaucoma
Ocular Hypertension
Eye Diseases

Interventions

DEVICE

No Results Yet

NCT02693535 | RECRUITING | PHASE2

4200 participants

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-03-14
Completion:: 2027-12-31

Conditions

Lymphoma, Non-Hodgkin
Multiple Myeloma
Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT02688140 | COMPLETED | PHASE3

133 participants

Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-06-30
Completion:: 2025-01-20

Conditions

Acute Promyelocytic Leukemia

Interventions

DRUG

No Results Yet

NCT02688036 | COMPLETED | PHASE3

860 participants

Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-02-29
Completion:: 2022-10-31

Conditions

Carcinoma, Small Cell
Lung Neoplasms

Interventions

RADIATION

No Results Yet

NCT02676089 | COMPLETED | PHASE3

1437 participants

TRIple in Asthma hiGh strenGth vErsus Ics/Laba hs and tiotRopium (TRIGGER)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-04-06
Completion:: 2018-05-28

Conditions

Asthma

Interventions

DRUG

Results Available

NCT02656381 | COMPLETED

343 participants

Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-07-26
Completion:: 2023-05-04

Conditions

Uveitis

No Results Yet

NCT02645149 | COMPLETED | PHASE2

216 participants

Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2021-11-22
Completion:: 2025-11-01

Conditions

Melanoma

Interventions

DRUG

No Results Yet

NCT02642042 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Trametinib and Docetaxel in Treating Patients With Recurrent or Stage IV KRAS Mutation Positive Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-07-18
Completion:: 2019-05-15

Conditions

KRAS Gene Mutation
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Non-Small Cell Cancer AJCC v7

Interventions

DRUG
OTHER

Results Available

NCT02639325 | RECRUITING

100 participants

Tumor Related Epilepsy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-01-26
Completion:: 2032-07-01

Conditions

Epilepsy
Cancer
Brain Neoplasm

No Results Yet

NCT02618551 | COMPLETED | NA

14 participants

Bronchial Thermoplasty for Severe Asthma With Dynamic Hyperinflation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2015-11-30
Completion:: 2021-05-06

Conditions

Asthma
Hyperinflation

Interventions

PROCEDURE

No Results Yet

NCT02617966 | RECRUITING

500 participants

Rod and Cone Mediated Function in Retinal Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-03-24
Completion:: 2029-12-30

Conditions

Retinal Degeneration
Retinitis Pigmentosa
Stargardt's Disease

No Results Yet

NCT02612454 | ACTIVE_NOT_RECRUITING | PHASE3

880 participants

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2015-10-15
Completion:: 2026-10-07

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT02597738 | ACTIVE_NOT_RECRUITING | NA

330 participants

A Feasibility Study to Further the Development of Lung Cancer-based Precision Medicine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-29
Start Date:: 2016-01-31
Completion:: 2027-12-31

Conditions

Lung Cancer
Head and Neck Cancer

Interventions

OTHER

No Results Yet