Clinical Trials

NCT05040204 | RECRUITING | PHASE1

44 participants

The Effects of Dietary Supplementation on Serum Protein Glycosylation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2022-06-23

Completion:

2026-11-22

Conditions

• Healthy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05038553 | ACTIVE_NOT_RECRUITING

125 participants

Chronic Pain in Rheumatoid Arthritis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2021-10-12

Completion:

2027-02-28

Conditions

• Arthritis, Rheumatoid
• Pain

Interventions

• OTHER

No Results Yet

NCT05035030 | RECRUITING | PHASE3

70 participants

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-09-03

Completion:

2026-12-31

Conditions

• Alagille Syndrome

Interventions

• DRUG

No Results Yet

NCT05026216 | COMPLETED | PHASE4

5 participants

To Assess the Effectiveness of Multiple Dose, Multiple Concentrations of Qwo, for the Treatment of Mild to Moderate Cellulite.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-03-29

Completion:

2021-08-15

Conditions

• Cellulite

Interventions

• DRUG

Results Available

NCT04993430 | ACTIVE_NOT_RECRUITING | PHASE1

46 participants

A Phase 1 Study of HRS8807 Monotherapy and in Combination With SHR6390 in Subjects With ER-Positive, HER2-Negative Metastatic or Locally Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-10-26

Completion:

2026-12-30

Conditions

• ER-Positive, HER2-Negative Breast Cancer

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04981223 | COMPLETED | NA

95 participants

Predicting Location and Extent of Prostate Cancer Using Micro-Ultrasound Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2022-04-01

Completion:

2024-01-26

Conditions

• Prostate Cancer

Interventions

• DEVICE

Results Available

NCT04974710 | COMPLETED

100 participants

Developing an US-MRI Biomarker Fusion Model for Endometriosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2022-03-18

Completion:

2023-03-31

Conditions

• Endometriosis
• Reproductive System Disorder

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04953910 | RECRUITING | PHASE1

27 participants

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2022-12-23

Completion:

2026-12-31

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT04953897 | RECRUITING | PHASE1

18 participants

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-12-15

Completion:

2026-12-31

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT04924075 | RECRUITING | PHASE2

322 participants

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-08-12

Completion:

2029-06-04

Conditions

• Pheochromocytoma/Paraganglioma
• Pancreatic Neuroendocrine Tumor
• Von Hippel-Lindau Disease
• Advanced Gastrointestinal Stromal Tumor
• HIF-2α Mutated Cancers

Interventions

• DRUG

No Results Yet

NCT04921137 | RECRUITING | PHASE4

500 participants

Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-08-19

Completion:

2036-05-31

Conditions

• Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04919980 | RECRUITING | NA

65 participants

TVMR With the INNOVALVE System Trial - Early Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2022-09-01

Completion:

2026-07-01

Conditions

• Mitral Valve Regurgitation (Degenerative or Functional)

Interventions

• DEVICE

No Results Yet

NCT04913766 | COMPLETED | NA

1206 participants

REstoring Mental Health Through COmmUnity-based Psychological Services in New York City

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2022-10-25

Completion:

2026-02-09

Conditions

• Depression
• Anxiety
• Psychological Distress
• PTSD

Interventions

• BEHAVIORAL

No Results Yet

NCT04896827 | SUSPENDED

244 participants

DNIC Using Deep Learning and Artificial Intelligence

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2022-04-05

Completion:

2028-12-31

Conditions

• Chronic Pain

Interventions

• OTHER

No Results Yet

NCT04855656 | RECRUITING | PHASE1

464 participants

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-04-30

Completion:

2027-12-31

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04824066 | RECRUITING

2400 participants

The Role of Wearable Devices in Predicting and Detecting Complications and Adverse Events

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2021-07-10

Completion:

2029-01-01

Conditions

• Recovery
• Treatment Complication

Interventions

• DEVICE

No Results Yet

NCT04818502 | ACTIVE_NOT_RECRUITING

200 participants

Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2021-05-04

Completion:

2024-04-04

Conditions

• Mitral Valve Regurgitation

Interventions

• DEVICE

No Results Yet

NCT04818268 | TERMINATED | NA

120 participants

Sensory Memory in Speech Motor Learning

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2019-08-01

Completion:

2025-07-31

Conditions

• Speech
• Consolidation

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04816643 | COMPLETED | PHASE3

11837 participants

Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-03-24

Completion:

2023-10-04

Conditions

• SARS-CoV-2 Infection, COVID-19

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04794530 | RECRUITING | PHASE3

190 participants

The COCOA-PAD II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-11-19

Completion:

2026-12-31

Conditions

• Peripheral Artery Disease

Interventions

• DRUG

No Results Yet

NCT04766723 | COMPLETED | PHASE2

78 participants

A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-02-24

Completion:

2023-04-26

Conditions

• Essential Tremor of the Upper Limb

Interventions

• DRUG

Results Available

NCT04721665 | COMPLETED

1681 participants

German SLD-Registry (Deutsches SLD-Register)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-28

Start Date:

2020-12-01

Completion:

2026-04-16

Conditions

• Steatotic Liver Disease

No Results Yet

NCT04640779 | COMPLETED | PHASE1

22 participants

Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-02-08

Completion:

2025-11-19

Conditions

• Recurrent Histiocytic and Dendritic Cell Neoplasm
• Recurrent Hodgkin Lymphoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Plasma Cell Myeloma
• Refractory Histiocytic and Dendritic Cell Neoplasm
• Refractory Hodgkin Lymphoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Plasma Cell Myeloma

Interventions

• DRUG

No Results Yet

NCT04606264 | COMPLETED | PHASE3

3395 participants

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2023-05-15

Completion:

2025-03-21

Conditions

• Perioperative Optimization

Interventions

• DRUG

Results Available

NCT04603807 | ACTIVE_NOT_RECRUITING | PHASE3

220 participants

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-09-30

Completion:

2028-06-26

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT04568616 | ACTIVE_NOT_RECRUITING | PHASE2

178 participants

Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-08-13

Completion:

2028-04-02

Conditions

• Breast Cancer
• ER Positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04550676 | COMPLETED | NA

118 participants

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-04-02

Completion:

2025-01-24

Conditions

• Hiv
• Fatigue
• Mobility Limitation

Interventions

• BEHAVIORAL

Results Available

NCT04542733 | ACTIVE_NOT_RECRUITING | NA

50 participants

The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus and Leflunomide in Treatment of BK Virus Infection in Kidney Transplantation Recipient

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2023-06-15

Completion:

2027-12-31

Conditions

• Kidney Transplant Infection
• BK Virus Infection

Interventions

• DRUG

No Results Yet

NCT04533763 | COMPLETED | NA

326 participants

Living WELL: A Web-Based Program for Ovarian Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-09-30

Completion:

2026-01-07

Conditions

• Ovarian Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04521231 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

181 participants

A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-01-04

Completion:

2027-11-24

Conditions

• B Cell Precursor Acute Lymphoblastic Leukemia

Interventions

• DRUG

No Results Yet

NCT04514484 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-11-22

Completion:

2024-11-11

Conditions

• Advanced Differentiated Thyroid Gland Carcinoma
• Advanced Head and Neck Carcinoma
• Advanced Hepatocellular Carcinoma
• Advanced Kaposi Sarcoma
• Advanced Lung Non-Small Cell Carcinoma
• Advanced Lung Small Cell Carcinoma
• Advanced Malignant Solid Neoplasm
• Advanced Melanoma
• Advanced Ovarian Carcinoma
• Advanced Prostate Carcinoma
• Advanced Renal Cell Carcinoma
• Advanced Thyroid Gland Medullary Carcinoma
• Advanced Triple-Negative Breast Carcinoma
• Advanced Urothelial Carcinoma
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Castration-Resistant Prostate Carcinoma
• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• HIV Infection
• Metastatic Differentiated Thyroid Gland Carcinoma
• Metastatic Head and Neck Carcinoma
• Metastatic Hepatocellular Carcinoma
• Metastatic Kaposi Sarcoma
• Metastatic Lung Non-Small Cell Carcinoma
• Metastatic Lung Small Cell Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic Melanoma
• Metastatic Ovarian Carcinoma
• Metastatic Prostate Carcinoma
• Metastatic Renal Cell Carcinoma
• Metastatic Thyroid Gland Medullary Carcinoma
• Metastatic Triple-Negative Breast Carcinoma
• Metastatic Urothelial Carcinoma
• Recurrent Differentiated Thyroid Gland Carcinoma
• Recurrent Head and Neck Carcinoma
• Recurrent Hepatocellular Carcinoma
• Recurrent Kaposi Sarcoma
• Recurrent Lung Non-Small Cell Carcinoma
• Recurrent Lung Small Cell Carcinoma
• Recurrent Malignant Solid Neoplasm
• Recurrent Melanoma
• Recurrent Ovarian Carcinoma
• Recurrent Prostate Carcinoma
• Recurrent Renal Cell Carcinoma
• Recurrent Thyroid Gland Medullary Carcinoma
• Recurrent Triple-Negative Breast Carcinoma
• Recurrent Urothelial Carcinoma
• Refractory Differentiated Thyroid Gland Carcinoma
• Stage III Differentiated Thyroid Gland Carcinoma AJCC v8
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage III Lung Cancer AJCC v8
• Stage III Ovarian Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage III Renal Cell Cancer AJCC v8
• Stage III Thyroid Gland Medullary Carcinoma AJCC v8
• Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IV Prostate Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IV Thyroid Gland Medullary Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT04493372 | RECRUITING | NA

69 participants

Deciphering Preserved Autonomic Function After Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-11-13

Completion:

2026-09-08

Conditions

• Spinal Cord Injuries
• Autonomic Imbalance
• Autonomic Dysreflexia
• Orthostatic Hypotension

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04469959 | COMPLETED | PHASE2

79 participants

Dopaminergic Dysfunction in Late-Life Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-02-15

Completion:

2026-04-29

Conditions

• Late Life Depression
• Cognitive Decline
• Depressive Disorder, Treatment-Resistant
• Levodopa
• Gait Impairment

Interventions

• DRUG

No Results Yet

NCT04403165 | COMPLETED | NA

30 participants

Locus-coeruleus Function in Normal Elderly and AD Risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-08-06

Completion:

2024-03-26

Conditions

• Alzheimer Disease

Interventions

• PROCEDURE
• OTHER
• BEHAVIORAL

No Results Yet

NCT04360395 | ACTIVE_NOT_RECRUITING | NA

120 participants

Igniting Mobility in Adolescents and Young Adults With Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-08-03

Completion:

2026-05-26

Conditions

• Cerebral Palsy

Interventions

• BEHAVIORAL

No Results Yet

NCT04336722 | ACTIVE_NOT_RECRUITING | PHASE3

254 participants

Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-07-08

Completion:

2026-06-22

Conditions

• Biliary Atresia

Interventions

• DRUG

No Results Yet

NCT04305054 | COMPLETED | PHASE1/PHASE2

335 participants

Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-07-01

Completion:

2026-05-18

Conditions

• Melanoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04248829 | COMPLETED | PHASE3

393 participants

Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2020-02-13

Completion:

2022-07-29

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04247191 | TERMINATED | NA

2061 participants

Parent Intervention to Reduce College Student Drinking and Consequences

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-06-14

Completion:

2025-04-16

Conditions

• Underage Drinking
• Driving Under the Influence
• Drinking, Teen
• Drinking, College

Interventions

• BEHAVIORAL

No Results Yet

NCT04216316 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-28

Start Date:

2021-04-14

Completion:

2024-03-31

Conditions

• Lung Non-Small Cell Squamous Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

Results Available