Clinical Trials

NCT07237256 | RECRUITING | PHASE3

3902 participants

Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-18

Completion:

2033-11-30

Conditions

• Breast Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT07235202 | RECRUITING | PHASE1/PHASE2

45 participants

A Study of MR001 Combined With Chemotherapy in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) After First-line Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-24

Completion:

2028-06-22

Conditions

• Pancreatic Ductal Adenocarcinoma (PDAC)

Interventions

• DRUG

No Results Yet

NCT07234032 | NOT_YET_RECRUITING | PHASE3

344 participants

An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-06-05

Completion:

2031-01-22

Conditions

• Pulmonary Hypertension
• Interstitial Lung Disease

Interventions

• DRUG

No Results Yet

NCT07232498 | RECRUITING | NA

1300 participants

Early Doppler-Assisted Mobilization in Adults After Acute Ischemic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-06-04

Completion:

2026-12-31

Conditions

• Arterial Ischemic Stroke

Interventions

• PROCEDURE

No Results Yet

NCT07232030 | ENROLLING_BY_INVITATION | NA

2500 participants

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-04-30

Completion:

2033-01-31

Conditions

• Heart Failure
• Heart Failure NYHA Class II
• Heart Failure NYHA Class III

Interventions

• DEVICE
• OTHER

No Results Yet

NCT07228195 | NOT_YET_RECRUITING | PHASE4

40 participants

SGLT2i Therapy in Islet Transplantation (SIT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-07-15

Completion:

2028-12-01

Conditions

• Partial Islet Function
• TPIAT
• Diabetes

Interventions

• DRUG

No Results Yet

NCT07227857 | RECRUITING | PHASE1/PHASE2

20 participants

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-11-24

Completion:

2028-04-15

Conditions

• Epileptic Encephalopathy

Interventions

• DRUG

No Results Yet

NCT07227597 | RECRUITING | PHASE1/PHASE2

170 participants

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-01-29

Completion:

2030-11-29

Conditions

• Small Cell Lung Cancer Extensive Stage

Interventions

• DRUG

No Results Yet

NCT07227376 | RECRUITING

250 participants

Data Collection Using Eko Digital Devices in a Clinical Setting

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2025-09-14

Completion:

2027-04-01

Conditions

• Lung Diseases

Interventions

• DEVICE

No Results Yet

NCT07227311 | RECRUITING | PHASE2

200 participants

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-04-15

Completion:

2030-08-30

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT07226427 | RECRUITING | PHASE1

100 participants

A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-01-10

Completion:

2027-12-02

Conditions

• Platinum-resistant Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT07226245 | NOT_YET_RECRUITING | PHASE4

69 participants

Methadone Pharmacokinetics in Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-09-30

Completion:

2026-12-30

Conditions

• Postoperative Pain Management

Interventions

• DRUG

No Results Yet

NCT07226206 | RECRUITING | PHASE1/PHASE2

5 participants

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-06-30

Completion:

2031-07-31

Conditions

• Hemophilia A

Interventions

• DRUG

No Results Yet

NCT07225569 | RECRUITING | PHASE2

144 participants

A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-29

Completion:

2027-09-22

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

No Results Yet

NCT07221474 | RECRUITING | PHASE2

180 participants

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-12

Completion:

2029-07-02

Conditions

• Squamous Non-small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG
• OTHER

No Results Yet

NCT07221214 | RECRUITING | PHASE2

200 participants

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-04-17

Completion:

2029-10-31

Conditions

• HIV
• Alcohol
• Smoking Cigarette
• Cardiovascular Disease Prevention

Interventions

• DRUG

No Results Yet

NCT07218653 | NOT_YET_RECRUITING | EARLY_PHASE1

72 participants

Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-07-31

Completion:

2031-07-31

Conditions

• Metabolic Syndrome

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT07218029 | RECRUITING | PHASE3

815 participants

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-05-12

Completion:

2028-12-07

Conditions

• Pulmonary Arterial Hypertension

Interventions

• BIOLOGICAL

No Results Yet

NCT07216482 | RECRUITING | PHASE3

975 participants

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-11-11

Completion:

2026-12-02

Conditions

• Hyperlipidemia

Interventions

• DRUG

No Results Yet

NCT07216170 | NOT_YET_RECRUITING | NA

200 participants

REVascularization In Large VEssel Occlusion for Acute Ischemic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-12-31

Completion:

2027-12-31

Conditions

• Acute Ischemic Stroke

Interventions

• DEVICE

No Results Yet

NCT07214779 | RECRUITING | PHASE3

466 participants

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-09

Completion:

2028-11-15

Conditions

• Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT07213908 | RECRUITING | NA

1320 participants

Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-03-31

Completion:

2030-02-01

Conditions

• Sleep

Interventions

• BEHAVIORAL

No Results Yet

NCT07210515 | RECRUITING | PHASE3

270 participants

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-04-14

Completion:

2027-12-31

Conditions

• Complex Regional Pain Syndrome Type I

Interventions

• DRUG

No Results Yet

NCT07209111 | RECRUITING | PHASE2

150 participants

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-04

Completion:

2032-04-09

Conditions

• Neoplasm Malignant

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT07207850 | RECRUITING | NA

200 participants

Parents Helping Parents for Youth Vaping Cessation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-05-18

Completion:

2027-06-30

Conditions

• Implementation Science
• Engagement, Patient
• E Cigarette Use
• Peer Support
• Vaping Teens
• Vaping Cessation
• Parent Support

Interventions

• BEHAVIORAL

No Results Yet

NCT07205172 | RECRUITING

180 participants

Gingival Phenotype and Dental Crowding in Pediatric Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-16

Completion:

2026-10-31

Conditions

• Crowding, Tooth
• Gingival Diseases

Interventions

• OTHER

No Results Yet

NCT07196241 | RECRUITING

300 participants

Comprehensive Care for AYA: Needs Assessment Survey

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2026-06-30

Completion:

2026-08-31

Conditions

• Cancer
• Young Adult Cancer
• Adolescent Cancer

Interventions

• OTHER

No Results Yet

NCT07193888 | RECRUITING

100 participants

Navitor Japan Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2025-10-30

Completion:

2028-07-31

Conditions

• Severe Aortic Stenosis

Interventions

• DEVICE

No Results Yet

NCT07193511 | RECRUITING | PHASE1/PHASE2

355 participants

BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-10-02

Completion:

2030-03-31

Conditions

• Solid Tumor Cancer
• Locally Advanced
• Metastatic Solid Tumors
• Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT07190404 | RECRUITING | NA

114 participants

Multicontext Approach for Cognitive Function in Parkinson Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-05-20

Completion:

2029-08-31

Conditions

• PARKINSON DISEASE (Disorder)

Interventions

• BEHAVIORAL

No Results Yet

NCT07190248 | RECRUITING | PHASE3

675 participants

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-10-08

Completion:

2029-12-07

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT07185438 | RECRUITING | NA

45 participants

Feasibility, Safety, and Preliminary Clinical Efficacy of Magnetic Resonance Imaging-guided Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression: A Randomized, Double-Blind, Controlled Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-09-15

Completion:

2027-09-15

Conditions

• Depression - Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT07181681 | RECRUITING | PHASE1

63 participants

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-11-10

Completion:

2027-11-01

Conditions

• Solid Tumors
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT07181590 | RECRUITING | NA

300 participants

BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2025-12-11

Completion:

2027-08-31

Conditions

• Paroxysmal AF
• Atrial Arrhythmia
• Atrial Fibrillation
• Persistent Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT07181304 | NOT_YET_RECRUITING | NA

200 participants

Peer Support and Remote Patient Monitoring for Black Adults With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-06-15

Completion:

2028-06-30

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT07180966 | COMPLETED

780 participants

Development and Validation of the Surgical Assessment and Healthcare (SAH) Index for Gastric Cancer Treatment Evaluation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2019-01-02

Completion:

2025-07-28

Conditions

• Gastric Cancer (GC)

No Results Yet

NCT07176975 | NOT_YET_RECRUITING | PHASE1

46 participants

A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2027-08-03

Completion:

2028-12-19

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07176182 | RECRUITING | PHASE2

236 participants

Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-03-20

Completion:

2031-03-20

Conditions

• Rectal Cancer Patients
• Rectal Cancer Stage II
• Rectal Cancer Stage III

Interventions

• DRUG

No Results Yet

NCT07175376 | RECRUITING | NA

32 participants

Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-03-16

Completion:

2027-01-31

Conditions

• Cancer
• Frail
• Chemotherapy

Interventions

• OTHER

No Results Yet

NCT07172659 | RECRUITING | PHASE2

45 participants

Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2026-05-25

Completion:

2027-01-31

Conditions

• Erythema Nodosum Leprosum

Interventions

• DRUG

No Results Yet