MedTrace Logo

Early Doppler-Assisted Mobilization in Adults After Acute Ischemic Stroke

NCT07232498 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1300

Last updated 2026-01-29

No results posted yet for this study

Summary

Post-stroke mobilization remains a subject of ongoing debate. While early mobilization-particularly the first out-of-bed mobilization-has been associated with reduced systemic complications and earlier rehabilitation, it also carries potential risks, such as neurological deterioration in the presence of hemodynamic instability.

In this study, the primary aim is to investigate whether early mobilization, guided by hemodynamic evaluation after acute ischemic stroke offers superior outcomes compared to standard clinical care.

Conditions

  • Arterial Ischemic Stroke

Interventions

PROCEDURE

Doppler-guided early mobilization

Individualized early mobilization after ischemic stroke, guided by hemodynamic assessment using carotid and transcranial Doppler ultrasound. The type and timing of mobilization are adjusted according to the presence of significant hemodynamic alterations.

Sponsors & Collaborators

  • Unidade Local de Saúde São João

    collaborator OTHER_GOV

  • Unidade Local de Saúde Santa Maria

    collaborator OTHER_GOV

  • Unidade Local de Saúde de Coimbra, EPE

    lead OTHER

Principal Investigators

  • Joao Sargento Freitas, MD, PhD · Unidade Local de Saude de Coimbra

  • Joao Sargento Freitas, MD, PhD · Unidade Local de Saude de Coimbra

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-04
Primary Completion
2026-12-31
Completion
2027-12-31

Countries

  • Portugal

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07232498 on ClinicalTrials.gov