Clinical Trials

NCT05712356 | TERMINATED | PHASE2

66 participants

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-05-13

Completion:

2026-04-05

Conditions

• Cholangiocarcinoma
• Gallbladder Cancer
• Gallbladder Carcinoma
• Intrahepatic Cholangiocarcinoma
• Extrahepatic Cholangiocarcinoma
• Bile Duct Cancer
• Gall Bladder Cancer
• Gall Bladder Carcinoma

Interventions

• DRUG

Results Available

NCT05710679 | RECRUITING | NA

63 participants

Prediction of Residual Disease by Circulating DNA Detection After Potentiated Radiotherapy for Locally Advanced Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-01-17

Completion:

2029-04-30

Conditions

• Locally Advanced Head and Neck Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05709210 | RECRUITING | NA

90 participants

Pilot Study on the Feasibility of Using Smartphone Data as a Diagnostic Marker for Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-07-20

Completion:

2026-10-20

Conditions

• Alzheimer Disease
• Memory Disorders

Interventions

• OTHER

No Results Yet

NCT05706389 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Does Alpha-ketoglutarate Supplementation Lower BiologicaL agE in Middle- Aged Adults?

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-24

Completion:

2025-08-15

Conditions

• Aging

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05705193 | ACTIVE_NOT_RECRUITING | NA

40 participants

Brain-Training Treatment for Long COVID in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-04-07

Completion:

2026-06-30

Conditions

• Post-Acute COVID-19 Syndrome

Interventions

• OTHER

No Results Yet

NCT05687188 | RECRUITING

125 participants

Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-22

Completion:

2026-12-31

Conditions

• Pancreatic Cancer

Interventions

• OTHER

No Results Yet

NCT05686850 | RECRUITING | NA

670 participants

Non-Invasive Ventilation Versus High-flow Nasal Oxygen in Intensive Care Units

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-02

Completion:

2028-02-27

Conditions

• Post Extubation Respiratory Failure

Interventions

• PROCEDURE

No Results Yet

NCT05676086 | COMPLETED | NA

191 participants

Population Based Lighting Study on Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-01

Completion:

2024-02-08

Conditions

• Lightning Strategies on Health
• Circadian Rhythms Photoentrainment
• Photoentrainment and Sleep
• DLMO

Interventions

• BEHAVIORAL

Results Available

NCT05673408 | RECRUITING

189 participants

NIBP Validation Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-06-23

Completion:

2027-03-31

Conditions

• Critical Illness

Interventions

• DEVICE

No Results Yet

NCT05668988 | ACTIVE_NOT_RECRUITING | PHASE3

324 participants

A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-12-13

Completion:

2026-01-16

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05660642 | RECRUITING | PHASE2

64 participants

An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-10

Completion:

2026-11-30

Conditions

• Treatment Resistant Depression

Interventions

• DRUG

No Results Yet

NCT05656560 | ACTIVE_NOT_RECRUITING | NA

786 participants

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-06-08

Completion:

2026-05-11

Conditions

• Polypharmacy

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05643638 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-04

Completion:

2026-03-17

Conditions

• Graft Versus Host Disease, Acute

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05639569 | ACTIVE_NOT_RECRUITING

147 participants

Ankura™ TAA Stent Graft System Post-Market Clinical Follow-up Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-05-03

Completion:

2026-12-30

Conditions

• Aneurysm Thoracic
• Dissection of Thoracic Aorta

Interventions

• DEVICE

No Results Yet

NCT05637112 | ACTIVE_NOT_RECRUITING

551 participants

A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-02-27

Completion:

2030-12-30

Conditions

• Systemic Lupus Erythematosus

Interventions

• OTHER

No Results Yet

NCT05626088 | ACTIVE_NOT_RECRUITING

1006 participants

A Study in Adults With Inflammatory Bowel Disease (IBD) Receiving Vedolizumab in the Patient Support Program (PSP) in Brazil

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-04-10

Completion:

2024-12-27

Conditions

• Ulcerative Colitis
• Crohn's Disease

Interventions

• OTHER

No Results Yet

NCT05623397 | COMPLETED

70 participants

A Deep Learning Method to Evaluate QT on Ribociclib

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2023-07-28

Completion:

2025-10-08

Conditions

• Breast Cancer
• Ribociclib

Interventions

• OTHER

No Results Yet

NCT05620771 | RECRUITING | PHASE2

200 participants

Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-11-30

Completion:

2040-07-01

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT05609630 | RECRUITING | PHASE3

90 participants

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-10-02

Completion:

2029-06-30

Conditions

• Juvenile Idiopathic Arthritis

Interventions

• DRUG

No Results Yet

NCT05597735 | ACTIVE_NOT_RECRUITING | PHASE3

480 participants

Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-03-03

Completion:

2026-09-30

Conditions

• Monkeypox
• Mpox

Interventions

• DRUG

No Results Yet

NCT05593094 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

210 participants

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-09-03

Completion:

2027-08-31

Conditions

• Advanced Solid Tumors
• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05585580 | ACTIVE_NOT_RECRUITING | PHASE2

59 participants

Second-line Treatment With Serplulimab, Lenvatinib, and Paclitaxel in Advanced Gastric Cancer After Prior Immunotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-03-01

Completion:

2026-04-30

Conditions

• Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05583305 | ENROLLING_BY_INVITATION

60 participants

Prevalence and Etiologies of Intracranial Stenosis in Patients With Antiphospholipid Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2022-10-12

Completion:

2027-01-31

Conditions

• Antiphospholipid Syndrome
• Stenosis
• Intracranial Stenosis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05581121 | RECRUITING | PHASE3

510 participants

PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-12-20

Completion:

2033-12-20

Conditions

• Cervical Carcinoma
• Adenocarcinoma
• Adenosquamous Carcinoma

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT05579366 | RECRUITING | PHASE1/PHASE2

884 participants

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-12-07

Completion:

2027-07-31

Conditions

• High Grade Epithelial Ovarian Cancer
• High Grade Serous Ovarian Cancer
• Primary Peritoneal Carcinoma
• Fallopian Tube Cancer
• Endometrial Cancer
• Non-small Cell Lung Cancer
• Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)
• Mesothelioma
• Breast Adenocarcinoma
• Triple Negative Breast Cancer
• Hormone Receptor-positive/Her2 Negative Breast Cancer
• Platinum-resistant Ovarian Cancer (PROC)
• Platinum Sensitive Ovarian Cancer (PSOC)
• Primary Refractory Ovarian Cancer
• Uterine Cancer

Interventions

• DRUG

No Results Yet

NCT05577871 | COMPLETED | NA

36 participants

Dexmedetomidine in Off Pump Coronary Artery Bypass Grafting

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-11-01

Completion:

2023-02-28

Conditions

• Coronary Artery Disease

Interventions

• DRUG

No Results Yet

NCT05576896 | RECRUITING | PHASE2

43 participants

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-10-10

Completion:

2028-07-01

Conditions

• Stage IV Colorectal Cancer Positive for BRAF V600E Mutation
• Colorectal Cancer
• Colorectal Cancer Stage IV

Interventions

• DRUG

No Results Yet

NCT05573230 | COMPLETED | PHASE1

32 participants

A Drug Interaction Study of Cyclosporine and LY3502970 in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-10-17

Completion:

2023-01-17

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT05565170 | COMPLETED | NA

156 participants

Digitally Supported Lifestyle Programme to Promote Brain Health Among Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-01-30

Completion:

2025-05-12

Conditions

• Cognitive Impairment
• Cognitive Decline
• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT05564390 | RECRUITING | PHASE2

2000 participants

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-06-18

Completion:

2029-05-15

Conditions

• Acute Myeloid Leukemia
• Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm
• Acute Myeloid Leukemia Post Cytotoxic Therapy
• Acute Myeloid Leukemia, Myelodysplasia-Related
• Myelodysplastic Syndrome

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL
• RADIATION

No Results Yet

NCT05554328 | RECRUITING | PHASE2

165 participants

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-04-25

Completion:

2028-10-01

Conditions

• Recurrent Endometrial Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05551273 | COMPLETED | PHASE2

29 participants

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-05-05

Completion:

2025-10-29

Conditions

• Hepatitis B
• HIV Infections

Interventions

• DRUG

No Results Yet

NCT05546372 | RECRUITING | NA

122 participants

Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-10-22

Completion:

2027-06-30

Conditions

• Perihilar Cholangiocarcinoma

Interventions

• DEVICE

No Results Yet

NCT05509777 | RECRUITING | PHASE3

90 participants

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2024-03-13

Completion:

2027-12-31

Conditions

• Crohn's Disease

Interventions

• DRUG

No Results Yet

NCT05496959 | ACTIVE_NOT_RECRUITING | PHASE2

93 participants

177-Lutetium-PSMA Before Stereotactic Body Radiotherapy for the Treatment of Oligorecurrent Prostate Cancer, The LUNAR Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-09-02

Completion:

2032-09-01

Conditions

• Oligometastatic Prostate Carcinoma
• Prostate Adenocarcinoma
• Recurrent Prostate Adenocarcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• DRUG
• OTHER
• RADIATION

No Results Yet

NCT05480449 | RECRUITING | PHASE1/PHASE2

115 participants

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-09-20

Completion:

2027-09-20

Conditions

• B Cell Acute Lymphoblastic Leukemia (B-ALL)
• B Lineage Lymphoblastic Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05472792 | RECRUITING | PHASE2

90 participants

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-05-17

Completion:

2027-04-15

Conditions

• Breast Cancer
• Quality of Life

Interventions

• RADIATION
• DRUG

No Results Yet

NCT05445778 | ACTIVE_NOT_RECRUITING | PHASE3

520 participants

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-03-15

Completion:

2032-05-31

Conditions

• Ovarian Cancer
• Peritoneal Cancer
• Fallopian Tube Cancer

Interventions

• DRUG

No Results Yet

NCT05445583 | RECRUITING | NA

180 participants

Asthma and Technology in Emerging African American Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2023-08-01

Completion:

2026-12-31

Conditions

• Asthma

Interventions

• BEHAVIORAL

No Results Yet

NCT05438004 | COMPLETED | NA

100 participants

Ambulatory Childbirth Pathway Pilot Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-12-19

Completion:

2025-03-20

Conditions

• Pregnancy Related

Interventions

• OTHER

No Results Yet