Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

NCT05687188 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2026-02-09

No results posted yet for this study

Summary

This study will evaluate obesity-mediated mechanisms of pancreatic carcinogenesis in minority populations.

Conditions

Interventions

OTHER

Blood Sample Collection

Participants will have 40 mL of blood drawn at baseline/pre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.

OTHER

Tissue Sample Collection

At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.

OTHER

Data Collection

Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.

OTHER

Medical Image Collection

Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED
  • H. Lee Moffitt Cancer Center and Research Institute

    lead OTHER

Principal Investigators

  • Jennifer Permuth, PhD, MS · Moffitt Cancer Center

  • Mokenge Malafa, MD · Moffitt Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-22
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05687188 on ClinicalTrials.gov