Clinical Trials

NCT04752761 | RECRUITING | NA

50 participants

Compliance With PROMs Detection Through Digital Support and Correlation Compared Standard to Outpatient Detection in Knee Prosthetics

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-11-30

Completion:

2027-12-01

Conditions

• Approach-Approach Conflict
• Knee Discomfort

Interventions

• BEHAVIORAL

No Results Yet

NCT04749628 | COMPLETED | PHASE4

37 participants

Cannabidiol for Bilateral Total Knee Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-11-02

Completion:

2024-10-11

Conditions

• Pain, Postoperative
• Opioid Use
• Knee Osteoarthritis

Interventions

• OTHER
• DRUG

Results Available

NCT04731376 | ACTIVE_NOT_RECRUITING | PHASE1

56 participants

Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-01-25

Completion:

2024-11-26

Conditions

• Hypogonadism
• Malignant Urinary System Neoplasm
• Urinary System Disorder
• Urinary System Neoplasm

Interventions

• OTHER
• PROCEDURE
• DRUG

No Results Yet

NCT04728893 | RECRUITING | PHASE2

490 participants

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-04-05

Completion:

2029-01-04

Conditions

• Hematologic Malignancies
• Waldenstroms Macroglobulinaemia
• Non-Hodgkins Lymphoma
• Chronic Lymphocytic Leukaemia

Interventions

• DRUG

No Results Yet

NCT04727658 | TERMINATED | PHASE2

9 participants

Linac FRACtionated Radiosurgical THALamotomie in Tremors (FRACTHAL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-07-01

Completion:

2024-06-20

Conditions

• Essential Tremor
• Parkinsonian Disorders

Interventions

• RADIATION

No Results Yet

NCT04690530 | WITHDRAWN

0 participants

Cerebral Hemodynamics and Oxygenation in Critically Ill Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2026-03-01

Completion:

2027-03-01

Conditions

• Septic Shock

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04687306 | COMPLETED

33 participants

Reliability of Sacral Slope, Pelvic Femoral Motion and Cup Ante-inclination on AP Pelvic Radiographs in Healthy Pts

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2021-01-15

Completion:

2024-01-31

Conditions

• Healthy

Interventions

• DIAGNOSTIC_TEST

Results Available

NCT04680767 | COMPLETED | PHASE1

6 participants

A Study of LY3502970 in Healthy Male Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-03-29

Completion:

2021-07-03

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT04678154 | RECRUITING | PHASE3

1200 participants

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-05-07

Completion:

2026-09-30

Conditions

• Post Operative Surgical Site Infection

Interventions

• DRUG

No Results Yet

NCT04666727 | RECRUITING

30 participants

Role of Diet on the Microbiome of the Digestive System

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2020-09-29

Completion:

2027-01-01

Conditions

• Colorectal Carcinoma

No Results Yet

NCT04652115 | RECRUITING | PHASE2

42 participants

Defibrotide for the Treatment of Severe COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-01-01

Completion:

2026-06-01

Conditions

• Covid19

Interventions

• DRUG

No Results Yet

NCT04651010 | RECRUITING | NA

50 participants

Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-11-15

Completion:

2026-08-15

Conditions

• Middle Cerebral Artery Acute Ischemic Stroke

Interventions

• OTHER

No Results Yet

NCT04648904 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

71 participants

Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-11-24

Completion:

2026-11-30

Conditions

• Invasive Breast Cancer
• Post-mastectomy

Interventions

• RADIATION

No Results Yet

NCT04640636 | SUSPENDED | PHASE4

90 participants

IM Ketamine vs Midazolam for Suicidal ER Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-02-09

Completion:

2027-09-30

Conditions

• Depression, Unipolar
• Depression, Bipolar
• Suicidal Ideation

Interventions

• DRUG

No Results Yet

NCT04635397 | COMPLETED

61 participants

Immunomonitoring After Hematopoietic Stem Cell Transplantation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2021-02-03

Completion:

2024-09-13

Conditions

• Hematopoietic Stem Cell Transplantation

No Results Yet

NCT04628026 | RECRUITING | PHASE3

650 participants

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-09-13

Completion:

2029-03-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT04624204 | ACTIVE_NOT_RECRUITING | PHASE3

672 participants

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-12-08

Completion:

2027-10-28

Conditions

• Small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT04618913 | ACTIVE_NOT_RECRUITING

1 participants

Anticoagulation in Patients With Venous Thromboembolism and Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2020-12-14

Completion:

2026-06-30

Conditions

• Neoplasms
• Embolism

Interventions

• DRUG

No Results Yet

NCT04609046 | RECRUITING | PHASE1

47 participants

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-05-24

Completion:

2027-04-01

Conditions

• Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04588545 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

33 participants

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-12-10

Completion:

2027-04-30

Conditions

• HER2-positive Breast Cancer
• Leptomeningeal Metastasis
• Leptomeningeal Disease

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04578678 | COMPLETED

105 participants

Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2019-08-09

Completion:

2026-03-31

Conditions

• Parkinson's Disease
• Deep Brain Stimulation

Interventions

• OTHER

No Results Yet

NCT04524533 | COMPLETED | NA

440 participants

VR Smoking Cessation During a Dental Hygiene Visit

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-01-04

Completion:

2025-03-19

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04523857 | RECRUITING | PHASE2

44 participants

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-11-01

Completion:

2027-12-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04504604 | RECRUITING | NA

400 participants

TCF-001 TRACK (Target Rare Cancer Knowledge) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-10-01

Completion:

2028-09-30

Conditions

• Rare Cancers
• Cholangiocarcinoma
• Cancer of Unknown Primary Site

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04502511 | RECRUITING

5000 participants

Heterogeneity of Critical Illness: a Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2022-01-01

Completion:

2030-01-01

Conditions

• Critically Ill
• Organ Failure, Multiple

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04492800 | COMPLETED | NA

9 participants

Hair Loss Prevention Study for Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2019-12-13

Completion:

2021-04-20

Conditions

• Alopecia

Interventions

• DEVICE

Results Available

NCT04460170 | COMPLETED

122 participants

COVID-19 Follow up Intensive Care Studies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2020-07-01

Completion:

2022-02-01

Conditions

• Quality of Life
• COVID-19

No Results Yet

NCT04426474 | COMPLETED | PHASE1

68 participants

A Study of LY3502970 in Participants With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-10-08

Completion:

2021-07-12

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT04401111 | ACTIVE_NOT_RECRUITING

90 participants

One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2020-06-16

Completion:

2029-10-31

Conditions

• COVID
• ARDS
• Quality of Life

No Results Yet

NCT04384328 | TERMINATED | NA

76 participants

Evaluation of an Early Support Programme in Orthophony

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2019-11-27

Completion:

2022-12-31

Conditions

• Language Development Disorders
• Preterm Birth

Interventions

• OTHER

No Results Yet

NCT04384263 | COMPLETED | NA

19 participants

The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults With Hypertension (ACTION)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-06-01

Completion:

2023-06-30

Conditions

• Hypertension
• Cognitive Decline

Interventions

• BEHAVIORAL

No Results Yet

NCT04378439 | RECRUITING | NA

141 participants

Appalachian Partnership to Reduce Disparities (Aim 2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2022-04-01

Completion:

2027-05-31

Conditions

• HIV/AIDS
• STI
• HCV

Interventions

• BEHAVIORAL

No Results Yet

NCT04378192 | COMPLETED | NA

36 participants

Laryngeal Mask Airway as a Bridge for Intubation of Obese Patients for Sleeve Gastrectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2019-02-01

Completion:

2021-08-30

Conditions

• Bariatric Surgery Candidate

Interventions

• DEVICE

No Results Yet

NCT04378023 | RECRUITING

34 participants

Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Perihilar Cholangiocarcinoma. A Prospective Multicenter Study.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-26

Start Date:

2020-04-24

Completion:

2027-06-01

Conditions

• Unresectable Cholangiocarcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04377217 | COMPLETED | NA

17 participants

Computerized Facial Recognition for Automated Diagnosis of the Facio-Scapulo-Humeral Muscular Dystrophy (FSMHD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2019-03-05

Completion:

2026-02-04

Conditions

• Facio-Scapulo-Humeral Dystrophy

Interventions

• OTHER

No Results Yet

NCT04349475 | ACTIVE_NOT_RECRUITING | NA

40 participants

Therapeutic Omegas for Triglyceride Suppression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-11-29

Completion:

2026-04-30

Conditions

• Pregnancy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04298203 | COMPLETED | PHASE2

100 participants

Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2021-08-04

Completion:

2026-05-22

Conditions

• Obesity

Interventions

• DRUG
• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT04296162 | COMPLETED | PHASE2

182 participants

Oral Vinorelbine or Capecitabine Combined With Trastuzumab as Adjuvant Treatment for Patients With Lymph Node Negative, HER-2 Positive and Small Tumor Size Breast Cancer (ORCHID)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-03-10

Completion:

2026-04-25

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04267848 | RECRUITING | PHASE3

1210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-06-16

Completion:

2027-01-31

Conditions

• Lung Non-Small Cell Carcinoma
• Lung Non-Small Cell Squamous Carcinoma
• Lung Non-Squamous Non-Small Cell Carcinoma
• Stage II Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL

No Results Yet

NCT04263025 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

100 participants

AMNIOX CORD Study - Radical Prostatectomy With and Without Cryopreserved Umbilical Cord Allograft

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-26

Start Date:

2020-01-30

Completion:

2027-04-01

Conditions

• Prostate Cancer

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet