Clinical Trials

NCT06750146 | SUSPENDED | NA

162 participants

Hot AXIOS™ for Bile Duct Drainage in Malignant Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-19

Completion:

2027-05-31

Conditions

• Malignant Biliary Stenosis

Interventions

• DEVICE

No Results Yet

NCT06750120 | RECRUITING | NA

1532 participants

Addressing the Double Burden of Malnutrition in Guatemala

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-14

Completion:

2029-05-31

Conditions

• Maternal Obesity Complicating Pregnancy, Birth,or Puerperium
• Child Malnutrition

Interventions

• DIETARY_SUPPLEMENT
• BEHAVIORAL
• OTHER

No Results Yet

NCT06749496 | COMPLETED | NA

134 participants

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-07

Completion:

2025-03-20

Conditions

• Astigmatism

Interventions

• DEVICE

Results Available

NCT06748053 | ACTIVE_NOT_RECRUITING | PHASE2

307 participants

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-10

Completion:

2026-07-17

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT06747533 | ACTIVE_NOT_RECRUITING | NA

40 participants

Impact of Diaphragmatic Breathing Coaching on Deep Inspiration Breath Hold Reproducibility and Organ Protection

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-08

Completion:

2026-12-31

Conditions

• Breathing, Mouth

Interventions

• OTHER

No Results Yet

NCT06746883 | RECRUITING

100 participants

A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-04-28

Completion:

2029-01-31

Conditions

• Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

Interventions

• OTHER

No Results Yet

NCT06746753 | NOT_YET_RECRUITING | PHASE4

78 participants

Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic Shock

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-07-31

Completion:

2028-07-31

Conditions

• Septic Shock

Interventions

• DRUG

No Results Yet

NCT06746155 | RECRUITING

252 participants

Predictors of Relapse in Major Depressive Disorder (PERFORM-D)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-27

Completion:

2028-10-01

Conditions

• Major Depressive Disorder (MDD)

No Results Yet

NCT06745921 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-24

Completion:

2026-10-01

Conditions

• West Nile Viral Infection

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06744036 | RECRUITING | NA

138 participants

Effects of Including Interferential Current in a Therapeutic Exercise Program in Individuals With Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-20

Completion:

2026-06-30

Conditions

• Osteoarthritis, Knee

Interventions

• OTHER
• DEVICE

No Results Yet

NCT06743282 | ENROLLING_BY_INVITATION | NA

60 participants

Senyo Health With Substance Use Disorder (SUD) in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-09-22

Completion:

2027-07-20

Conditions

• Substance Use Disorders
• Substance Abuse

Interventions

• BEHAVIORAL

No Results Yet

NCT06742996 | RECRUITING | PHASE3

300 participants

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-03-05

Completion:

2028-08-31

Conditions

• Mantle Cell Lymphoma
• B Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT06736080 | NOT_YET_RECRUITING | PHASE1/PHASE2

5 participants

Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced ex Vivo With the UNC13D LV Vector Expressing the UNC13D cDNA

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-31

Completion:

2029-01-31

Conditions

• Familial Hemophagocytic Lymphohistiocytosis Type 3 (FHL 3)

Interventions

• GENETIC

No Results Yet

NCT06735209 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-07-23

Completion:

2027-02-01

Conditions

• Malaria

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06731777 | COMPLETED | NA

45 participants

Oral Gel Containing PHTALOX® as an Adjuvant in the Treatment of Periodontal Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2023-01-05

Completion:

2024-10-05

Conditions

• Periodontitis

Interventions

• PROCEDURE

No Results Yet

NCT06731660 | COMPLETED | NA

40 participants

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-01

Completion:

2025-04-30

Conditions

• Otitis Media
• Antimicrobial Stewardship

Interventions

• OTHER
• DEVICE

No Results Yet

NCT06731166 | RECRUITING | NA

140 participants

Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-01

Completion:

2027-06-01

Conditions

• Heart Failure With Reduced Ejection Fraction (HFrEF)

Interventions

• BEHAVIORAL

No Results Yet

NCT06727604 | RECRUITING | PHASE2

240 participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-17

Completion:

2028-06-30

Conditions

• Graves' Disease

Interventions

• DRUG

No Results Yet

NCT06722235 | RECRUITING | PHASE3

171 participants

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-27

Completion:

2028-03-16

Conditions

• Immune Thrombocytopenic Purpura (ITP)

Interventions

• DRUG

No Results Yet

NCT06717347 | RECRUITING | PHASE3

1046 participants

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-27

Completion:

2029-07-02

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06712654 | NOT_YET_RECRUITING | PHASE2

168 participants

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2026-05-31

Completion:

2027-02-28

Conditions

• Hyperphosphatemia
• Chronic Kidney Disease Requiring Chronic Dialysis
• End Stage Renal Disease on Dialysis

Interventions

• DRUG

No Results Yet

NCT06712368 | COMPLETED | NA

40 participants

Effect of Virtual Reality on Pain, Arterial Blood Gases and Functional Capacity in Children After Open Heart Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-08-10

Completion:

2025-01-10

Conditions

• Children After Open Heart Surgery

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06712316 | RECRUITING | PHASE2/PHASE3

1260 participants

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-07

Completion:

2029-02-28

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06709872 | RECRUITING

400 participants

A Prospective Multicenter Diagnostic Biomarker Study to Discriminate Borderline From Stage I Invasive Ovarian Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-06-03

Completion:

2029-09-03

Conditions

• Stage I Ovarian Cancer
• Borderline Ovarian Tumors

No Results Yet

NCT06709521 | RECRUITING | PHASE4

200 participants

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-12

Completion:

2026-06-30

Conditions

• Bacterial Infection

Interventions

• DRUG

No Results Yet

NCT06704724 | TERMINATED | PHASE1

30 participants

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-10

Completion:

2026-05-12

Conditions

• Carcinoma, Pancreatic Ductal
• Colorectal Neoplasms
• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT06698848 | ACTIVE_NOT_RECRUITING | PHASE1

120 participants

Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-01-01

Completion:

2030-06-01

Conditions

• Depression
• Suicide

Interventions

• DRUG

No Results Yet

NCT06692543 | RECRUITING | NA

60 participants

Sedentary or Exercised : Neuromuscular and Immunometabolic Observations and Retrospection

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-04-14

Completion:

2028-04-30

Conditions

• Aging

Interventions

• OTHER

No Results Yet

NCT06686394 | RECRUITING | PHASE1/PHASE2

81 participants

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-26

Completion:

2030-04-18

Conditions

• Breast Neoplasms
• Breast Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT06685718 | TERMINATED | PHASE1

33 participants

A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-05

Completion:

2026-04-21

Conditions

• Non-Small Cell Lung Cancer
• Lung Cancer
• NSCLC
• NSCLC (Non-small Cell Lung Carcinoma)
• EGFR Activating Mutation
• EGFR Mutation-Related Tumors

Interventions

• DRUG

No Results Yet

NCT06681935 | RECRUITING

40 participants

Defining Mechanisms of Surgical Site Infection After Oral Cancer Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2025-04-29

Completion:

2026-07-15

Conditions

• Oral Cancer

Interventions

• PROCEDURE

No Results Yet

NCT06679634 | RECRUITING | PHASE2

30 participants

Retinoblastoma Phase II Expanded Access Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2025-02-21

Completion:

2029-11-30

Conditions

• Retinoblastoma

Interventions

• DRUG

No Results Yet

NCT06679140 | RECRUITING | PHASE3

2330 participants

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-08

Completion:

2027-10-03

Conditions

• COVID-19 SARS-CoV-2 Infection

Interventions

• DRUG

No Results Yet

NCT06672172 | COMPLETED | PHASE3

284 participants

A Study of HRS-7535 Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Diet and Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-09-25

Completion:

2025-11-13

Conditions

• Type 2 Diabetes

Interventions

• DRUG

No Results Yet

NCT06669416 | RECRUITING | NA

400 participants

Taste Alterations Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-01

Completion:

2026-09-30

Conditions

• Taste, Altered
• Chemotherapy Side Effects

Interventions

• BEHAVIORAL

No Results Yet

NCT06668246 | COMPLETED

43 participants

Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-22

Start Date:

2022-10-01

Completion:

2023-04-30

Conditions

• Refractive Errors
• Ametropia

Interventions

• DEVICE

No Results Yet

NCT06666673 | RECRUITING | EARLY_PHASE1

64 participants

Effect of Neural Constraints on Movement in Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-08-23

Completion:

2029-06-30

Conditions

• Stroke

Interventions

• DRUG

No Results Yet

NCT06665256 | RECRUITING | PHASE2

123 participants

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-17

Completion:

2029-03-09

Conditions

• Idiopathic Inflammatory Myopathies

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06664619 | RECRUITING | PHASE3

724 participants

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-12-12

Completion:

2026-05-31

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT06656390 | RECRUITING | PHASE1/PHASE2

202 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK201 in Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-22

Start Date:

2024-10-24

Completion:

2027-10-22

Conditions

• Advanced Cancer
• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet