Clinical Trials

NCT04823858 | ACTIVE_NOT_RECRUITING

176 participants

3Spine Lumbar Fusion Real World Evidence Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-05-25

Completion:

2025-12-23

Conditions

• Lumbar Spine Degeneration

Interventions

• DEVICE

No Results Yet

NCT04798261 | RECRUITING

1500 participants

Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-06-25

Completion:

2026-12-31

Conditions

• Pulmonary Embolism

Interventions

• DEVICE

No Results Yet

NCT04798131 | RECRUITING | NA

84 participants

fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-08-26

Completion:

2026-07-31

Conditions

• Schizophrenia
• Hallucinations, Auditory
• Hallucinations, Visual

Interventions

• OTHER

No Results Yet

NCT04786743 | COMPLETED | NA

412 participants

Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-04-20

Completion:

2026-02-11

Conditions

• Acute Upper Gastrointestinal Hemorrhage
• Cirrhosis
• Varice Bleed
• Gastroesophageal Varices

Interventions

• OTHER

No Results Yet

NCT04769960 | ACTIVE_NOT_RECRUITING

68 participants

Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-02-19

Completion:

2027-02-19

Conditions

• Breast Cancer
• Breast Neoplasms
• Breast Adenocarcinoma

Interventions

• DIAGNOSTIC_TEST
• BEHAVIORAL

No Results Yet

NCT04769206 | RECRUITING | PHASE1/PHASE2

160 participants

Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-12-20

Completion:

2027-05-31

Conditions

• Endothelial Dysfunction

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04761120 | RECRUITING

550 participants

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-02-01

Completion:

2030-11-30

Conditions

• Mitral Regurgitation
• Tricuspid Regurgitation
• Valvular Heart Disease

Interventions

• DEVICE

No Results Yet

NCT04742101 | COMPLETED | PHASE1/PHASE2

57 participants

Phase I/II Trial of S65487 Plus Azacitidine in Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-03-10

Completion:

2026-03-27

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04731272 | RECRUITING | PHASE2

30 participants

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-07-16

Completion:

2027-06-30

Conditions

• Cystic Fibrosis
• Pancreatic Insufficiency
• Abnormal Glucose Tolerance
• Diabetes

Interventions

• DRUG

No Results Yet

NCT04722666 | TERMINATED | PHASE2

199 participants

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-07-20

Completion:

2023-09-26

Conditions

• Major Depressive Disorder With Suicidal Ideation With Intent

Interventions

• DRUG

Results Available

NCT04718896 | COMPLETED | PHASE2

41 participants

A Study to Assess the Pharmacokinetics, Safety, and Efficacy of Two Doses of Bimekizumab in Adolescent Study Participants With Moderate to Severe Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-04-06

Completion:

2025-03-12

Conditions

• Moderate to Severe Plaque Psoriasis

Interventions

• DRUG

Results Available

NCT04718389 | COMPLETED | PHASE3

1717 participants

A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-01-26

Completion:

2025-09-14

Conditions

• Asthma

Interventions

• BIOLOGICAL
• DRUG
• DEVICE

Results Available

NCT04701645 | RECRUITING | PHASE1

20 participants

Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-11-01

Completion:

2027-06-05

Conditions

• Ovarian Cancer
• Fallopian Tube Cancer
• Peritoneal Cancer
• Ovarian Cancer Stage III
• Ovarian Cancer Stage IV
• Fallopian Tube Cancer Stage IV
• Fallopian Tube Cancer Stage III

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04669457 | ENROLLING_BY_INVITATION | PHASE4

60 participants

Pediatric Delirium

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-04-27

Completion:

2027-04-05

Conditions

• Pediatric Delirium

Interventions

• DRUG

No Results Yet

NCT04661007 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

72 participants

To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-12-15

Completion:

2025-07-01

Conditions

• Non Hodgkins Lymphoma
• Diffuse Large B-cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT04626479 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

400 participants

Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-12-16

Completion:

2026-07-17

Conditions

• Carcinoma, Renal Cell

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04614714 | NOT_YET_RECRUITING | PHASE2/PHASE3

40 participants

Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2026-06-01

Completion:

2026-06-30

Conditions

• Preterm Birth
• Inadequate Milk Production

Interventions

• OTHER

No Results Yet

NCT04554927 | ACTIVE_NOT_RECRUITING | NA

438 participants

Impact of Web Application Support Versus Standard Management on Compliance With Adjuvant Hormone Therapy at 18 Months in Patients Treated for Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-09-03

Completion:

2024-10-11

Conditions

• Web-application
• Breast Cancer
• Hormono Therapy

Interventions

• OTHER

No Results Yet

NCT04553185 | COMPLETED

733 participants

Aquaporin-4 Single Nucleotide Polymorphisms in Patients With Idiopathic and Familial Parkinson's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-11-28

Completion:

2026-04-30

Conditions

• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04515810 | RECRUITING | NA

400 participants

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2025-02-18

Completion:

2026-08-31

Conditions

• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT04483089 | ACTIVE_NOT_RECRUITING

511 participants

An Observational Real-world Study Evaluating Severe Tricuspid Regurgitation Patients Treated With the Abbott TriClip™ Device (bRIGHT)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-27

Completion:

2027-12-31

Conditions

• Tricuspid Valve Regurgitation

Interventions

• DEVICE

No Results Yet

NCT04455906 | RECRUITING

111 participants

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2020-11-30

Completion:

2027-03-15

Conditions

• Atopic Dermatitis

No Results Yet

NCT04455048 | COMPLETED | NA

84 participants

The Effectiveness of Manipulation Treatment in Cervical Region

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-02-02

Completion:

2023-03-16

Conditions

• Neck Pain

Interventions

• OTHER

No Results Yet

NCT04432597 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

39 participants

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-11

Completion:

2022-11-22

Conditions

• HPV Positive Cancer
• Vulvar, Vaginal, Penile, Rectal Cancer
• Anal Cancer
• Oropharyngeal Cancer
• Cervical Cancer

Interventions

• BIOLOGICAL
• DIAGNOSTIC_TEST
• PROCEDURE
• DRUG

No Results Yet

NCT04421820 | RECRUITING | PHASE1/PHASE2

220 participants

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-28

Completion:

2026-06-01

Conditions

• Colorectal Cancer
• Pancreatic Cancer
• Gastric Cancers
• Cholangiocarcinoma

Interventions

• DRUG

No Results Yet

NCT04399876 | ENROLLING_BY_INVITATION | PHASE1

35 participants

Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-06-22

Completion:

2027-08-01

Conditions

• Prostate Cancer
• Radical Prostatectomy

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04390906 | ACTIVE_NOT_RECRUITING

75 participants

A Study of Cognitive Changes in Patients Receiving Brain Radiation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-10-16

Completion:

2027-01-01

Conditions

• Brain Tumor Adult

No Results Yet

NCT04380441 | ACTIVE_NOT_RECRUITING

206 participants

Quality of Life Model for Older Patients With AML

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2020-07-08

Completion:

2023-11-30

Conditions

• AML, Adult
• Acute Myeloid Leukemia

No Results Yet

NCT04370054 | ACTIVE_NOT_RECRUITING | PHASE3

77 participants

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-18

Completion:

2024-06-17

Conditions

• Hemophilia A

Interventions

• BIOLOGICAL

Results Available

NCT04309487 | RECRUITING

20 participants

Diagnostic Accuracy of ShuntCheck Compared to Radionuclide Shunt: Patency in Patients With Normal Pressure Hydrocephalus

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2020-01-24

Completion:

2027-01-31

Conditions

• Hydrocephalus, Normal Pressure

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04309383 | COMPLETED

12 participants

ShuntCheck Performance Characteristics in Asymptomatic Pseudotumor Cerebri Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2019-10-29

Completion:

2026-02-05

Conditions

• Pseudotumor Cerebri

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04305470 | COMPLETED | PHASE3

108 participants

Gleolan for Visualization of Newly Diagnosed or Recurrent Meningioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-10-28

Completion:

2022-11-07

Conditions

• Meningioma

Interventions

• DRUG

Results Available

NCT04299945 | RECRUITING | NA

15 participants

Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2024-08-07

Completion:

2026-12-31

Conditions

• Interstitial Lung Disease

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04257318 | COMPLETED | NA

32 participants

Clitoris Potential Analgesic Function Research by Pregnant Women : Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-11

Completion:

2022-11-02

Conditions

• Pregnancy Related

Interventions

• OTHER

No Results Yet

NCT04229563 | COMPLETED

102 participants

Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-04

Completion:

2021-03-17

Conditions

• Infrainguinal Peripheral Artery Disease
• Peripheral Arterial Disease
• PAD

Interventions

• DEVICE

Results Available

NCT04200768 | ACTIVE_NOT_RECRUITING | NA

150 participants

FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-09-01

Completion:

2028-10-31

Conditions

• Breast Neoplasms

Interventions

• OTHER

No Results Yet

NCT04187703 | RECRUITING | EARLY_PHASE1

20 participants

5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-11-16

Completion:

2026-11-01

Conditions

• Myelodysplastic Syndromes
• MDS/MPN Crossover Syndromes

Interventions

• DRUG

No Results Yet

NCT04165109 | RECRUITING

550 participants

Trial-Ready Cohort-Down Syndrome (TRC-DS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-06-07

Completion:

2027-12-31

Conditions

• Down Syndrome
• Alzheimer Disease
• Dementia

No Results Yet

NCT04165070 | RECRUITING | PHASE1/PHASE2

450 participants

KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-12-19

Completion:

2032-02-13

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04154956 | TERMINATED | PHASE3

389 participants

SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small-cell Lung Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-02-06

Completion:

2023-09-22

Conditions

• Non-small Cell Lung Cancer Metastatic

Interventions

• DRUG

Results Available