Clinical Trials

NCT05614063 | COMPLETED | PHASE3

380 participants

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-11-18
Completion:: 2026-01-12

Conditions

Focal Onset Seizures

Interventions

DRUG

No Results Yet

NCT05612178 | ACTIVE_NOT_RECRUITING | PHASE1

105 participants

A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-07-26
Completion:: 2027-03-31

Conditions

HIV-1

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05605366 | NOT_YET_RECRUITING | PHASE1

30 participants

Minocycline In Neurocognitive Outcomes - Sickle Cell Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-12-01
Completion:: 2027-12-31

Conditions

Sickle Cell Disease
Cognitive Impairment
Cognitive Decline
Cognitive Change
Cognitive Dysfunction
Cognitive Deficit
Neuroinflammatory Response

Interventions

DRUG

No Results Yet

NCT05602038 | COMPLETED | NA

100 participants

Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-02-01
Completion:: 2023-12-01

Conditions

Chronic Post Cesarean Pain

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05591222 | TERMINATED | PHASE2

72 participants

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-12-29
Completion:: 2025-05-08

Conditions

Discoid Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT05576207 | COMPLETED | NA

3390 participants

BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-10-15
Completion:: 2025-04-24

Conditions

Preterm Birth
Fetal Growth Retardation
Low Birth Weight
Gestational Weight Gain
Anemia of Pregnancy
Stunting
Pregnancy Complications

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05572957 | ACTIVE_NOT_RECRUITING | NA

50 participants

LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-10-14
Completion:: 2027-10-31

Conditions

Non-ischemic Cardiomyopathy
Heart Failure
Left Bundle-Branch Block

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05567562 | COMPLETED | PHASE2

15 participants

Anti-Platelets in Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2024-03-27
Completion:: 2025-02-28

Conditions

COPD
Emphysema
Emphysema or COPD

Interventions

COMBINATION_PRODUCT
DRUG

Results Available

NCT05566795 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-02-27
Completion:: 2027-06-30

Conditions

Low-grade Glioma
Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma
Pediatric Low-grade Glioma

Interventions

DRUG

No Results Yet

NCT05556876 | COMPLETED | NA

123 participants

Effect of Oral Nutritional Supplements to Older Patients Discharged With a Rehabilitation Plan

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-12-01
Completion:: 2025-09-30

Conditions

Nutritional Risk
Rehabilitation
Oral Nutritional Supplements

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05554341 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-07-14
Completion:: 2027-06-30

Conditions

Metastatic Malignant Solid Neoplasm
Refractory Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05552443 | TERMINATED | PHASE4

31 participants

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-03-23
Completion:: 2024-10-27

Conditions

Pain Control

Interventions

DRUG

Results Available

NCT05548296 | RECRUITING | PHASE2

401 participants

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-08-29
Completion:: 2027-05-30

Conditions

Endometrial Adenocarcinoma

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT05543330 | RECRUITING | PHASE1/PHASE2

96 participants

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-09-30
Completion:: 2026-09-15

Conditions

Malignant Pleural Effusions
NSCLC Stage IV

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05541627 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-10-12
Completion:: 2024-04-04

Conditions

Huntington Disease

Interventions

GENETIC

No Results Yet

NCT05536414 | COMPLETED | PHASE2

337 participants

Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-09-12
Completion:: 2025-05-16

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05536115 | COMPLETED

120 participants

Impact of Treatment With ALVEOGYL in Patients With Post-extraction Dry Socket

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-12-13
Completion:: 2025-06-26

Conditions

Dry Socket

Interventions

DEVICE

Results Available

NCT05535738 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

45 participants

Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-11-15
Completion:: 2027-01-01

Conditions

Skin Inflammation
Allergic Contact Dermatitis

Interventions

DRUG
OTHER
DEVICE
PROCEDURE

No Results Yet

NCT05535387 | COMPLETED | NA

42 participants

Integrated Smart Speaker Promoting Positive Parenting Among Caregivers of Youth With Challenging Behaviors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2024-03-11
Completion:: 2024-12-15

Conditions

Oppositional Defiant Disorder
Conduct Disorder

Interventions

BEHAVIORAL

Results Available

NCT05530434 | TERMINATED | NA

4 participants

Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-04-11
Completion:: 2026-04-14

Conditions

Respiratory Failure
Obesity

Interventions

OTHER

No Results Yet

NCT05514938 | COMPLETED | PHASE2

140 participants

Polypill in Acute Coronary Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-11-30
Completion:: 2025-05-30

Conditions

Acute Coronary Syndrome
Lipid Disorder
Coronary Artery Disease

Interventions

DRUG

Results Available

NCT05512377 | TERMINATED | PHASE2

99 participants

Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-12-13
Completion:: 2025-09-25

Conditions

Pancreatic Neoplasms
Solid Tumors
Biliary Tract Cancer
Lung Neoplasms
Bladder Cancer

Interventions

DRUG

No Results Yet

NCT05497219 | ENROLLING_BY_INVITATION | NA

580 participants

Reference Values for Videofluoroscopic Measures of Swallowing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-11-15
Completion:: 2026-11-30

Conditions

Dysphagia, Oropharyngeal

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05481931 | COMPLETED

756 participants

Non Interventional Safety Study of NUCEIVA for the Treatment of Moderate-to-Severe Glabellar Lines

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-03-15
Completion:: 2026-02-04

Conditions

Glabellar Frown Lines

Interventions

DRUG

No Results Yet

NCT05463133 | RECRUITING | PHASE1/PHASE2

50 participants

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-07-08
Completion:: 2032-12-31

Conditions

Chronic Granulomatous Disease

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05455814 | COMPLETED | NA

77 participants

Brain Health With Inner Engineering Meditation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-01-06
Completion:: 2025-12-16

Conditions

Meditation
Brain; Agenesis

Interventions

BEHAVIORAL

No Results Yet

NCT05447806 | RECRUITING | NA

15732 participants

Diabetes Clinical Decision Support

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-07-15
Completion:: 2025-10-16

Conditions

Hyperglycemia
Hyperglycemia Stress
Diabetes
PreDiabetes
Hypoglycemia

Interventions

DEVICE

No Results Yet

NCT05445843 | ACTIVE_NOT_RECRUITING | PHASE2

95 participants

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-12-06
Completion:: 2024-11-04

Conditions

Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation

Interventions

DRUG

Results Available

NCT05430815 | COMPLETED | NA

320 participants

Improving Women's Health Through Coordinated Postpartum Planning

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-08-08
Completion:: 2024-07-31

Conditions

Maternal Death
Maternal Morbidity

Interventions

BEHAVIORAL

Results Available

NCT05429632 | RECRUITING | PHASE3

366 participants

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-06-16
Completion:: 2027-05-31

Conditions

Adult Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05425004 | RECRUITING | PHASE2

24 participants

Cabozantinib for Patients With Recurrent or Progressive Meningioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-06-01
Completion:: 2026-12-31

Conditions

Meningioma

Interventions

DRUG

No Results Yet

NCT05423301 | COMPLETED | NA

245 participants

Global Physiotherapy in ICU Patients With High Risk Extubation Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-10-03
Completion:: 2026-05-07

Conditions

Acute Respiratory Failure

Interventions

PROCEDURE

No Results Yet

NCT05413850 | RECRUITING | PHASE1/PHASE2

82 participants

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-07-20
Completion:: 2026-08-27

Conditions

Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
mCRPC
Urogenital Neoplasms
Prostatic Neoplasms
Prostatic Diseases

Interventions

DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT05405387 | RECRUITING | PHASE2

120 participants

Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-05-03
Completion:: 2026-05-19

Conditions

Multiple Myeloma
Plasma Cell Leukemia

Interventions

DRUG

No Results Yet

NCT05404945 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and Above

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-07-26
Completion:: 2027-10-03

Conditions

Classical Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05403151 | RECRUITING

1000 participants

Controls and Healthy Vasculature Initiative

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-07-01
Completion:: 2032-01-30

Conditions

Vascular And Immunologic Diseases
Healthy Volunteers

No Results Yet

NCT05388760 | COMPLETED | PHASE2

28 participants

Tralokinumab Monotherapy for Children With Moderate-to-severe Atopic Dermatitis - TRAPEDS 1 (TRAlokinumab PEDiatric Trial no. 1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-09-07
Completion:: 2023-10-20

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT05379166 | ACTIVE_NOT_RECRUITING | PHASE2

33 participants

Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-06-23
Completion:: 2026-01-27

Conditions

Secondary Myelodysplastic Syndrome
Therapy-Related Myelodysplastic Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT05374603 | ACTIVE_NOT_RECRUITING | PHASE2

47 participants

Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-11-15
Completion:: 2027-01-18

Conditions

Lung Cancer

Interventions

DRUG

No Results Yet

NCT05374187 | COMPLETED | NA

218 participants

Efficacy of Trigeminal Nerve Stimulation for ADHD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2022-09-01
Completion:: 2026-04-10

Conditions

Attention-Deficit Hyperactivity Disorder

Interventions

DEVICE

No Results Yet