MedTrace Logo

Reference Values for Videofluoroscopic Measures of Swallowing

NCT05497219 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 580

Last updated 2026-05-14

No results posted yet for this study

Summary

Dysphagia (swallowing impairment) is a serious health condition seen in many age-related disease and injury processes. Although videofluoroscopy (VF) is an international "gold standard" dysphagia diagnostic exam, there is a paucity of available normative physiologic VF reference values in healthy adults across the age span to guide interpretation of these examinations. In this project, the investigators will extend previous work on the quantitative measurement of swallowing physiology from VF examinations to establish reference values for swallowing in healthy adults, and to identify clinical decision point values for differentiating healthy swallowing across the age span from disordered swallowing in several high-risk clinical populations to study dysphagia.

Conditions

  • Dysphagia, Oropharyngeal

Interventions

DIAGNOSTIC_TEST

Videofluoroscopic Swallowing Study (VF)

A videofluoroscopy (VF) is a dynamic radiological evaluation of swallowing in which the participant swallows liquid or food boluses of different consistencies prepared with barium contrast. The x-rays are recorded at 30 frames per second.

Sponsors & Collaborators

  • University of Florida

    collaborator OTHER

  • McMaster University

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • Ohio State University

    collaborator OTHER

  • University of Cincinnati

    collaborator OTHER

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Catriona M Steele, PhD · University Health Network, Toronto

  • Emily K Plowman, PhD · Ohio State University

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-11-15
Primary Completion
2026-11-30
Completion
2027-07-31

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05497219 on ClinicalTrials.gov