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Clinical Trials

NCT05491980 | ACTIVE_NOT_RECRUITING
72 participants

Florida Cerebrovascular Disease Biorepository and Genomics Center

Study Type:
OBSERVATIONAL
Last Updated:
2026-05-13
Start Date:
2022-08-02
Completion:
2026-06-30
Conditions
  • Cerebrovascular Disease
  • Ischemic Stroke
  • Transient Ischemic Attack
  • Intracerebral Hemorrhage
  • Aneurysmal Subarachnoid Hemorrhage
  • Vascular Dementia
  • Anoxic Brain Injury
  • Unruptured Intracranial Aneurysm
  • Carotid Artery Stenosis Symptomatic
  • Asymptomatic Carotid Artery Stenosis
  • Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage
  • Cerebral Venous Thrombosis
  • Moyamoya Disease
  • Fibromuscular Dysplasia
  • Subarachnoid Hemorrhage
  • Leukoaraiosis
  • Arteriovenous Fistula
  • Reversible Cerebral Vasoconstriction Syndrome
  • CADASIL
No Results Yet
NCT05422794 | RECRUITING | PHASE1
57 participants

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2023-05-18
Completion:
2027-03-31
Conditions
  • Anatomic Stage III Breast Cancer AJCC v8
  • Anatomic Stage IV Breast Cancer AJCC v8
  • Locally Advanced Triple-Negative Breast Carcinoma
  • Metastatic Triple-Negative Breast Carcinoma
  • Unresectable Triple-Negative Breast Carcinoma
Interventions
  • DRUG
  • PROCEDURE
  • BIOLOGICAL
No Results Yet
NCT05422326 | COMPLETED | PHASE2
260 participants

A Study to Evaluate Safety and Immunogenicity of One or Two Booster Vaccinations With H5N6 Influenza Vaccine in Adults Primed With H5N1 Influenza Vaccine or Unprimed

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-07-18
Completion:
2022-10-24
Conditions
  • Influenza, Human
  • Influenza in Birds
  • Respiratory Tract Infections
  • Infections
  • Orthomyxoviridae Infections
  • RNA Virus Infections
  • Virus Diseases
  • Respiratory Tract Diseases
Interventions
  • BIOLOGICAL
Results Available
NCT05372640 | RECRUITING | PHASE1
45 participants

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2023-08-10
Completion:
2026-06-01
Conditions
  • Anatomic Stage III Breast Cancer AJCC v8
  • Anatomic Stage IV Breast Cancer AJCC v8
  • Metastatic Breast Carcinoma
  • Metastatic Malignant Solid Neoplasm
  • Metastatic NUT Carcinoma
  • Unresectable Breast Carcinoma
  • Unresectable Malignant Solid Neoplasm
  • Unresectable NUT Carcinoma
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
NCT05360888 | COMPLETED | NA
302 participants

Suicide Intervention for Alaska Native Youth

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-12-22
Completion:
2026-01-31
Conditions
  • Alaska Native Youth Aged 14 - 24
  • Suicide, Attempted
  • Suicidal Ideation
  • Alcohol Intoxication
Interventions
  • BEHAVIORAL
No Results Yet
NCT05353439 | ACTIVE_NOT_RECRUITING | PHASE1
18 participants

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-07-27
Completion:
2026-02-11
Conditions
  • Extensive Stage Lung Small Cell Carcinoma
  • Limited Stage Lung Small Cell Carcinoma
  • Platinum-Resistant Lung Small Cell Carcinoma
  • Platinum-Sensitive Lung Small Cell Carcinoma
  • Recurrent Extensive Stage Lung Small Cell Carcinoma
  • Recurrent Lung Small Cell Carcinoma
Interventions
  • PROCEDURE
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT05333458 | RECRUITING | PHASE2
27 participants

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-08-29
Completion:
2027-05-01
Conditions
  • Advanced Alveolar Soft Part Sarcoma
  • Advanced Soft Tissue Sarcoma
  • Metastatic Alveolar Soft Part Sarcoma
  • Refractory Alveolar Soft Part Sarcoma
  • Unresectable Alveolar Soft Part Sarcoma
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • DRUG
No Results Yet
NCT05327868 | COMPLETED | NA
32 participants

Lean and Obese: Dietary Inflammation

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-03-01
Completion:
2023-01-01
Conditions
  • Obesity
  • Inflammation
  • Dietary Fat
Interventions
  • OTHER
No Results Yet
NCT05286801 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
86 participants

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-11-17
Completion:
2030-03-31
Conditions
  • Atypical Teratoid/Rhabdoid Tumor
  • Epithelioid Sarcoma
  • Kidney Medullary Carcinoma
  • Malignant Solid Neoplasm
  • Poorly Differentiated Chordoma
  • Recurrent Atypical Teratoid/Rhabdoid Tumor
  • Recurrent Chordoma
  • Recurrent Epithelioid Sarcoma
  • Recurrent Kidney Medullary Carcinoma
  • Recurrent Malignant Solid Neoplasm
  • Recurrent Rhabdoid Tumor
  • Refractory Atypical Teratoid/Rhabdoid Tumor
  • Refractory Chordoma
  • Refractory Epithelioid Sarcoma
  • Refractory Kidney Medullary Carcinoma
  • Refractory Malignant Solid Neoplasm
  • Refractory Rhabdoid Tumor
  • Rhabdoid Tumor
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • OTHER
No Results Yet
NCT05272384 | RECRUITING | PHASE1
32 participants

Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-11-03
Completion:
2027-06-28
Conditions
  • Recurrent B-Cell Non-Hodgkin Lymphoma
  • Recurrent Diffuse Large B-Cell Lymphoma
  • Recurrent Hodgkin Lymphoma
  • Refractory B-Cell Non-Hodgkin Lymphoma
  • Refractory Diffuse Large B-Cell Lymphoma
  • Refractory Hodgkin Lymphoma
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT05172258 | ACTIVE_NOT_RECRUITING | PHASE2
52 participants

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-13
Start Date:
2022-07-26
Completion:
2027-06-30
Conditions
  • Head and Neck Squamous Cell Carcinoma
  • Metastatic Head and Neck Squamous Cell Carcinoma
  • Metastatic Hypopharyngeal Squamous Cell Carcinoma
  • Metastatic Laryngeal Squamous Cell Carcinoma
  • Metastatic Oral Cavity Squamous Cell Carcinoma
  • Metastatic Oropharyngeal Squamous Cell Carcinoma
  • Recurrent Head and Neck Squamous Cell Carcinoma
  • Recurrent Hypopharyngeal Squamous Cell Carcinoma
  • Recurrent Laryngeal Squamous Cell Carcinoma
  • Recurrent Oral Cavity Squamous Cell Carcinoma
  • Recurrent Oropharyngeal Squamous Cell Carcinoma
  • Stage IV Hypopharyngeal Carcinoma AJCC v8
  • Stage IV Laryngeal Cancer AJCC v8
  • Stage IV Lip and Oral Cavity Cancer AJCC v8
  • Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
  • PROCEDURE
  • DRUG
  • BIOLOGICAL
No Results Yet
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