Clinical Trials

NCT07581912 | RECRUITING | PHASE2

40 participants

Neoadjuvant Treatment of Fulzerasib Plus Cetuximab N01 in KRAS G12C Mutated Locally Advanced Colorectal Cancer With or Without Resectable Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-04-30
Completion:: 2028-12-31

Conditions

Colorectal Cancer
KRAS G12C Mutant Advanced Solid Tumors
Fulzerasib
Cetuximab N01

Interventions

DRUG

No Results Yet

NCT07581899 | RECRUITING | NA

70 participants

Mind Your Heart Intervention for American Indian Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-04-07
Completion:: 2026-07-31

Conditions

Cardiovascular Health

Interventions

BEHAVIORAL

No Results Yet

NCT07581886 | NOT_YET_RECRUITING | NA

78 participants

sACB vs cACB in TKA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-18
Completion:: 2028-01-10

Conditions

Arthroplasty
Replacement
Knee

Interventions

PROCEDURE

No Results Yet

NCT07581860 | NOT_YET_RECRUITING

10 participants

Growth Hormone Resistance of Beta-cells

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-08-01
Completion:: 2028-09-01

Conditions

Healthy
Obesity & Overweight
Impaired Fasting Glucose (IFG)
Impaired Glucose Tolerance (Prediabetes)

No Results Yet

NCT07581834 | RECRUITING | PHASE2

2000 participants

Efficacy and Safety of Dalpiciclib Combined With Endocrine Adjuvant Therapy for Early HR +/HER2- Breast Cancer: a Multicenter, Prospective Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-01-21
Completion:: 2031-12-31

Conditions

Breast Diseases
Breast Neoplasms
Dalpiciclib
Endocrine Breast Diseases
CDK4/6 Inhibitor
HR+/HER2- Breast Cancer

Interventions

DRUG

No Results Yet

NCT07581821 | RECRUITING | PHASE2

33 participants

Sintilimab Combined With Anlotinib and Taxane-Based Chemotherap for Recurrent/Metastatic Nasopharyngeal Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-09-15
Completion:: 2027-12-31

Conditions

Recurrent or Metastatic Nasopharyngeal Carcinoma

Interventions

DRUG

No Results Yet

NCT07581808 | NOT_YET_RECRUITING | PHASE4

60 participants

Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-31
Completion:: 2027-05-31

Conditions

Hypercholesterolemia
Atherosclerotic Cardiovascular Disease (ASCVD)

Interventions

DRUG

No Results Yet

NCT07581795 | NOT_YET_RECRUITING | PHASE2

140 participants

Study of Paclitaxel Polymeric Micelles Combined With HP and Adebelimab Versus Taxane Combined With HP as First-Line Treatment for Advanced HER2-Positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-30
Completion:: 2029-02-28

Conditions

Advanced HER2-positive Breast Cancer

Interventions

DRUG

No Results Yet

NCT07581782 | NOT_YET_RECRUITING

50 participants

Prospective, Single Arm, Observational Study of Faricimab in the Treatment of Neovascular Age-related Macular Degeneration (nAMD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-01
Completion:: 2028-05-31

Conditions

Neovascular Age-related Macular Degeneration(nAMD)

No Results Yet

NCT07581756 | RECRUITING | NA

46 participants

Repeated Transcranial Magnetic Stimulation for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2024-12-01
Completion:: 2026-07-01

Conditions

Irritable Bowel Syndrome
Irritable Bowel Syndrome With Diarrhea (IBS-D)
Repetitive Transcranial Magnetic Stimulation (rTMS)
Chronic Diarrhea
Intestinal Flora

Interventions

DEVICE

No Results Yet

NCT07581743 | NOT_YET_RECRUITING | NA

45 participants

How Can Different Forms of Strengthening Exercises Affect the Muscular Tissue and Its Chemical Markers in Children With Duchenne Muscular Dystrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-01
Completion:: 2026-08-15

Conditions

Duchene Muscular Dystrophy

Interventions

OTHER

No Results Yet

NCT07581717 | RECRUITING

12 participants

Computer-Assisted Comparison of Hip Socket Volume and Surface Shape After Pediatric Acetabular Osteotomies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-10
Completion:: 2026-09-30

Conditions

Developmental Dysplasia of the Hip (DDH)
Developmental Dysplasia of the Hip
Acetabular Dysplasia

Interventions

PROCEDURE

No Results Yet

NCT07581704 | NOT_YET_RECRUITING | PHASE1

10 participants

Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-30
Completion:: 2029-05-01

Conditions

Multiple Myeloma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07581691 | RECRUITING

200 participants

Evaluation of Preoperative Gastric Ultrasonography in Pediatric Patients in Terms of Patient Safety

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2024-11-15
Completion:: 2026-07-31

Conditions

Nonoperating Room Anesthesia
Gastric Ultrasound

No Results Yet

NCT07581678 | COMPLETED

120 participants

Artificial Intelligence Evaluation of Fascial Plane Block Quality and Postoperative Pain in Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-09-01
Completion:: 2026-05-01

Conditions

Pain, Postoperative
Cardiac Surgical Procedures
Nerve Block

No Results Yet

NCT07581665 | NOT_YET_RECRUITING | PHASE4

40 participants

Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-01
Completion:: 2026-08-30

Conditions

Pediatric Anesthesia
Airway Management
General Anesthesia
LMA

Interventions

DRUG

No Results Yet

NCT07581652 | COMPLETED

19 participants

ICGA for Vascular Embolism After Hyaluronic Acid Injection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-07-01
Completion:: 2026-03-30

Conditions

Embolism Arterial

Interventions

OTHER

No Results Yet

NCT07581587 | NOT_YET_RECRUITING | NA

54 participants

Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-31
Completion:: 2027-05-31

Conditions

Heart Failure

Interventions

BEHAVIORAL

No Results Yet

NCT07581561 | COMPLETED

318 participants

Predictors of Unilateral Spinal Block Success

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-08-10
Completion:: 2026-02-01

Conditions

Spinal Aneshtesia
Unilateral Spinal Anesthesia
Regional Anaesthesia

No Results Yet

NCT07581548 | NOT_YET_RECRUITING

300 participants

Evaluation of the Effectiveness of Three Tear Substitute Formulations in Postoperative Discomfort After Cataract Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-01
Completion:: 2026-12-31

Conditions

Cataract
Dry Eye

Interventions

DRUG

No Results Yet

NCT07581535 | NOT_YET_RECRUITING | NA

38 participants

Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-07
Completion:: 2027-06-07

Conditions

Chronic Ankle Instability, CAI

Interventions

OTHER

No Results Yet

NCT07581522 | COMPLETED | NA

19 participants

Pharmacokinetics of Essential Oils in Different Capsules

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-07-02
Completion:: 2025-12-19

Conditions

Healthy
Health, Subjective

Interventions

OTHER

No Results Yet

NCT07581483 | NOT_YET_RECRUITING | NA

500 participants

Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2027-06-01
Completion:: 2030-06-01

Conditions

Autism
Neurodevelopment

Interventions

BEHAVIORAL

No Results Yet

NCT07581470 | NOT_YET_RECRUITING | NA

198 participants

Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty: A Randomized Double-Blind Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-07-01
Completion:: 2027-06-30

Conditions

Osteoarthritis, Hip
Hip Osteoarthritis

Interventions

DRUG

No Results Yet

NCT07581457 | NOT_YET_RECRUITING | NA

90 participants

Tranexamic Acid in Pediatric Idiopathic Scoliosis Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-01
Completion:: 2027-05-31

Conditions

Scoliosis Idiopathic
Scoliosis; Adolescence

Interventions

DRUG

No Results Yet

NCT07581444 | NOT_YET_RECRUITING | NA

384 participants

Early Prevention and Precision Management of Female Fertility Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-30
Completion:: 2026-10-31

Conditions

Female Fertility Decline
Diminished Ovarian Reserve
Reproductive Health
Infertility Prevention

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07581431 | NOT_YET_RECRUITING | PHASE1

100 participants

Study Evaluating ISM8969 in Healthy Adult and Elderly Participants and Obese Adult Participants at Risk of Cardiovascular Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-29
Completion:: 2027-01-29

Conditions

Healthy Subjects (HS)
Elderly Participants
Obese Adult Participants at Risk of Cardiovascular Disease

Interventions

DRUG

No Results Yet

NCT07581418 | NOT_YET_RECRUITING | NA

88 participants

Comparison of Methotrexate and Tofacitinib in Chronic Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-06-01
Completion:: 2026-12-01

Conditions

Chronic Plaque Psoriasis

Interventions

DRUG

No Results Yet

NCT07581405 | NOT_YET_RECRUITING | PHASE2

26 participants

GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-31
Completion:: 2028-05-31

Conditions

Gastric Adenocarcinoma
Gastric Cancer

Interventions

DRUG

No Results Yet

NCT07581392 | COMPLETED

405 participants

Reintervention Rates and Complications in Endovascular Aneurysm Repair (EVAR) and the Use of Colour Doppler Ultrasound (CDUS) and Computed Tomography Angiography (CTA) in Identifying Endoleak Complications

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-01-01
Completion:: 2026-03-01

Conditions

Aneurysm Abdominal

No Results Yet

NCT07581379 | ACTIVE_NOT_RECRUITING

1826 participants

Advancing Precision Lung Cancer Surveillance and Outcomes in Diverse Populations

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2012-01-31
Completion:: 2026-12-31

Conditions

Lung Neoplasms
Second Primary Lung Cancer (SPLC)
Non-Small Cell Lung Cancer (NSCLC), Stage I-IIIA
Lung Cancer (Diagnosis)

No Results Yet

NCT07581366 | COMPLETED | NA

53 participants

Posterior Flap Hydration of Clear Corneal Incisions in Cataract Surgery: Influence on Corneal Wound Tightness and Architecture

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2021-01-14
Completion:: 2021-03-31

Conditions

Hydration
Cataract Surgery

Interventions

PROCEDURE

No Results Yet

NCT07581353 | COMPLETED | NA

60 participants

Effect Of Psychoeducation On Substance Craving Levels And Psychological Resilience

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-08-20
Completion:: 2026-02-20

Conditions

Psychoeducation Study

Interventions

BEHAVIORAL

No Results Yet

NCT07581340 | COMPLETED | NA

66 participants

Using AI to Improve Sepsis Quality of Care in the Emergency Department

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2024-12-01
Completion:: 2025-08-01

Conditions

Sepsis

Interventions

BEHAVIORAL

No Results Yet

NCT07581327 | NOT_YET_RECRUITING | NA

1812 participants

Data-Driven Lay First Responder Program in Cameroon

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-09-30
Completion:: 2028-06-30

Conditions

Trauma
Injury

Interventions

BEHAVIORAL

No Results Yet

NCT07581314 | NOT_YET_RECRUITING | PHASE1/PHASE2

76 participants

Oral Zn-Telomir Monotherapy in Patients With Advanced or Metastatic Triple-Negative Breast Cancer (TNBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-31
Completion:: 2027-05-31

Conditions

Triple-Negative Breast Cancer (TNBC)
Advanced Triple-Negative Breast Cancer
Metastatic Triple-negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT07581301 | NOT_YET_RECRUITING

30 participants

Administering Atropine Through Autoinjectors Within Ambulance Services for Poisoning Patients in Sri Lanka's North Central Province

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-08-01
Completion:: 2026-12-31

Conditions

Pesticide Poisoning

Interventions

DEVICE

No Results Yet

NCT07581288 | NOT_YET_RECRUITING

50 participants

Measurement of Urinary Hormones in Patients With Abnormal Uterine Bleeding to Study Uterine Cancer Progression

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-31
Completion:: 2026-09-30

Conditions

Uterine Bleeding
Uterine Cancer
Uterine Neoplasms
Endometrial Cancer
Endometrial Hyperplasia
Endometrial Intraepithelial Neoplasia
Menstrual Cycle
Reproductive Endocrinology

No Results Yet

NCT07581275 | NOT_YET_RECRUITING

26 participants

Plasma Kinetics of Levobupivacaine After Transversus Abdominis Plane (TAP) Block in Abdominal Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-07-01
Completion:: 2026-12-01

Conditions

Abdominal Surgery Patients
Transversus Abdominis Plane (TAP) Block
Pharmacokinetic Analysis
Levobupivacaine
Local Anaesthetic Systemic Toxicity

Interventions

PROCEDURE

No Results Yet

NCT07581262 | NOT_YET_RECRUITING | NA

90 participants

Risk Perception Intervention for High-Risk Diabetic Foot

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2026-05-01
Completion:: 2026-12-31

Conditions

Diabetes Mellitus
Diabetic Foot Ulcer (DFU)
Risk Perception
Peripheral Neuropathy With Type 2 Diabetes

Interventions

BEHAVIORAL

No Results Yet