Clinical Trials

NCT05598879 | RECRUITING

5000 participants

Global Cardio Oncology Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-01
Completion:: 2029-07-01

Conditions

Breast Cancer
Hematologic Malignancy
Immune Checkpoint Inhibitor-Related Myocarditis
Cardiotoxicity
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT05592665 | ACTIVE_NOT_RECRUITING | NA

42 participants

PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-03-18
Completion:: 2027-01-16

Conditions

Renal Cell Carcinoma

Interventions

OTHER

No Results Yet

NCT05583552 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-06-05
Completion:: 2025-03-27

Conditions

Myelodysplastic Syndromes
Acute Myeloid Leukemia

Interventions

DRUG

Results Available

NCT05582850 | TERMINATED | PHASE1

29 participants

DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-11-24
Completion:: 2025-04-08

Conditions

Solid Tumor, Adult

Interventions

DRUG

Results Available

NCT05568680 | RECRUITING | PHASE1

42 participants

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-03-30
Completion:: 2027-12-31

Conditions

Ovarian Cancer
Cholangiocarcinoma Recurrent
Mesothelioma, Malignant

Interventions

BIOLOGICAL

No Results Yet

NCT05557877 | RECRUITING | PHASE2

60 participants

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-03-09
Completion:: 2027-01-30

Conditions

Breast Carcinoma

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT05545306 | RECRUITING | NA

120 participants

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-06-06
Completion:: 2027-02-02

Conditions

Obesity
Normal Physiology
Healthy Volunteers

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05541016 | RECRUITING | PHASE2

455 participants

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-02-21
Completion:: 2028-08-01

Conditions

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma
Stage I Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage II Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Interventions

PROCEDURE
DRUG
RADIATION
OTHER

No Results Yet

NCT05529654 | ACTIVE_NOT_RECRUITING | NA

100 participants

IMpella-Protected cArdiaC Surgery Trial (IMPACT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-09-21
Completion:: 2025-11-04

Conditions

Left Ventricular Dysfunction

Interventions

DEVICE

No Results Yet

NCT05499286 | COMPLETED | NA

37 participants

A Mindfulness-Based Intervention to Improve CPAP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2020-06-28
Completion:: 2025-05-31

Conditions

Obstructive Sleep Apnea (Moderate to Severe)
Obstructive Sleep Apnea

Interventions

OTHER

No Results Yet

NCT05496426 | TERMINATED | PHASE2

114 participants

A Study of KL130008 in Adults With Severe Alopecia Areata

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-11-09
Completion:: 2024-04-16

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT05492682 | RECRUITING | PHASE1

15 participants

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-02-02
Completion:: 2027-04-30

Conditions

Melanoma (Skin)
Triple-Negative Breast Cancer
Non-Small Cell Lung Cancer
Synovial Sarcoma
Myxoid Liposarcoma
Colorectal Cancer
Osteosarcoma
Sarcoma

Interventions

DRUG

No Results Yet

NCT05486520 | ENROLLING_BY_INVITATION | NA

40 participants

Low-field MRI for Breast Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-09-01
Completion:: 2026-09-15

Conditions

Breast Benign
Malignant Neoplasm of Breast
Breast Malignant Tumor

Interventions

DEVICE

No Results Yet

NCT05481879 | RECRUITING | PHASE1/PHASE2

116 participants

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-09-05
Completion:: 2029-07-31

Conditions

Myotonic Dystrophy Type 1 (DM1)

Interventions

DRUG

No Results Yet

NCT05472883 | TERMINATED | NA

23 participants

Identification of Human Biomarkers Predictive of Diabetes Remission in Type 2 Diabetes Patient (BARIAKINES)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-02-27
Completion:: 2025-08-27

Conditions

Type 2 Diabetes

Interventions

PROCEDURE

No Results Yet

NCT05471375 | ACTIVE_NOT_RECRUITING

250 participants

C-STAR Movement Database

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-08-19
Completion:: 2026-12-31

Conditions

Stroke
Parkinson Disease
Lower Limb Amputation Above Knee (Injury)
Lower Limb Amputation Below Knee (Injury)

Interventions

OTHER

No Results Yet

NCT05470504 | RECRUITING | PHASE2

25 participants

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-01-23
Completion:: 2028-01-30

Conditions

Insulin Receptor Mutation
Partial Lipodystrophy

Interventions

DRUG

No Results Yet

NCT05457166 | COMPLETED | NA

40 participants

Use of the KASPARD System for Fall Prevention in Nursing Homes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2025-07-07
Completion:: 2026-04-30

Conditions

Accidental Falls
Nursing Homes

Interventions

DEVICE

No Results Yet

NCT05454891 | COMPLETED | NA

30 participants

Extended Bolus for Meals in a Closed-loop System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-15
Completion:: 2024-12-19

Conditions

Type 1 Diabetes

Interventions

DEVICE

Results Available

NCT05451004 | RECRUITING | PHASE3

510 participants

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-02-10
Completion:: 2030-08-30

Conditions

Oropharyngeal Cancer

Interventions

OTHER
RADIATION

No Results Yet

NCT05438329 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

1123 participants

First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-19
Completion:: 2027-08-13

Conditions

Advanced Solid Tumor

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05420948 | RECRUITING | PHASE2

30 participants

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-10-17
Completion:: 2026-12-01

Conditions

Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Head and Neck Neoplasms
Head Cancer
Throat Carcinoma

Interventions

DRUG

No Results Yet

NCT05419037 | RECRUITING

90 participants

Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects With Lipodystrophy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-09-07
Completion:: 2028-03-01

Conditions

Lipodystrophy

No Results Yet

NCT05414526 | COMPLETED | NA

4655 participants

Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-01-31
Completion:: 2025-09-10

Conditions

HIV Infections
Hypertension

Interventions

OTHER

No Results Yet

NCT05413135 | COMPLETED | PHASE2

418 participants

Study of ARO-APOC3 in Adults With Dyslipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-07
Completion:: 2025-09-22

Conditions

Dyslipidemias

Interventions

DRUG

No Results Yet

NCT05393609 | RECRUITING

250 participants

Quality of Life and Surgery in Diverticular Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-04-22
Completion:: 2026-10-31

Conditions

Diverticulitis Colon
Quality of Life
Diverticular Disease of Left Side of Colon

Interventions

PROCEDURE
DIETARY_SUPPLEMENT

No Results Yet

NCT05385965 | COMPLETED | NA

211 participants

Meaning-Centered Pain Coping Skills Training for Cancer Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-02-09
Completion:: 2026-04-10

Conditions

Advanced Solid Tumor
Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05363709 | WITHDRAWN | PHASE2

0 participants

BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-10-18
Completion:: 2026-05-04

Conditions

HPV
Oropharyngeal Cancer

Interventions

DRUG

No Results Yet

NCT05357560 | COMPLETED | PHASE1

107 participants

A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-07-10
Completion:: 2025-12-11

Conditions

Malaria, Plasmodium Falciparum

Interventions

BIOLOGICAL

No Results Yet

NCT05353647 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-12
Completion:: 2027-10-31

Conditions

Sickle Cell Disease

Interventions

BIOLOGICAL

No Results Yet

NCT05351788 | RECRUITING | PHASE2

110 participants

SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-05-20
Completion:: 2026-08-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05336851 | RECRUITING

2000 participants

Emergency PWAS in Respiratory Infectious Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-04-11
Completion:: 2028-05-01

Conditions

Viral Infections
Bacterial Infections
Fungal Infections
Mixed Infection
Mycobacterium Infection
Infection of Uncertain Aetiology
Pneumonia
Sepsis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05322954 | TERMINATED | PHASE1

5 participants

Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2023-03-03
Completion:: 2024-03-07

Conditions

Methamphetamine Use Disorder
Substance-Related Disorders
Chemically-Induced Disorders
Substance Use Disorders
Stimulant-Use Disorder

Interventions

DRUG

No Results Yet

NCT05317221 | RECRUITING

60 participants

Developing Breast (Cancer) Organoids

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-09-01
Completion:: 2028-04-01

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT05296590 | ACTIVE_NOT_RECRUITING

50000 participants

Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2021-07-01
Completion:: 2023-12-31

Conditions

Bacteremia
Bacteremia Sepsis
Sepsis
Septic Shock
Severe Sepsis
Emergency Departments
Continuity of Patient Care

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05281835 | ACTIVE_NOT_RECRUITING

1000 participants

Follow-up of Elderly Subjects With Falls Recruited in the Geriatric Departments of Several French Hospitals

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-06-16
Completion:: 2026-12-31

Conditions

Falls in the Elderly

No Results Yet

NCT05272618 | RECRUITING

150 participants

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-02-14
Completion:: 2029-12-31

Conditions

Myocardial Infarction
Coronary Microvascular Dysfunction
Vasospasm, Coronary

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05269589 | RECRUITING | NA

44 participants

Home-based Heat Therapy for Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-02-18
Completion:: 2027-12-31

Conditions

Diabetes Mellitus, Type 2
Heat Exposure

Interventions

OTHER

No Results Yet

NCT05247788 | COMPLETED | NA

112 participants

Impaired Risk Awareness During Intoxication in DUI Offenders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-02-02
Completion:: 2025-03-01

Conditions

Alcohol Use

Interventions

BEHAVIORAL

Results Available

NCT05246514 | ACTIVE_NOT_RECRUITING | PHASE2

72 participants

A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-12
Start Date:: 2022-07-13
Completion:: 2024-11-04

Conditions

HER2-mutant Non-Small Cell Lung Cancer

Interventions

DRUG

Results Available