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Quality of Life and Surgery in Diverticular Disease

NCT05393609 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2026-05-12

No results posted yet for this study

Summary

Diverticular disease is one of the most common diseases of the gastrointestinal tract in industrial countries. Prevalence and admission rate due to diverticular disease increases.

Symptomatic patients usually present with acute uncomplicated or complicated diverticulitis. Recurrence rates of complicated diverticulitis are estimated to 10-30%. Recurrences, chronic complications or persisting pain, here collectively referred to as chronic diverticular disease, may be treated by elective sigmoidectomy. Currently, there is no specific criteria for elective surgery, but only a recommendation of a tailored approach depending on the patient's symptoms.

It is well established that diverticular disease has a negative impact on quality of life (QoL). Elective laparoscopic sigmoidectomy may increase QoL.

In this prospective study, we will prospectively examine QoL, patient-related outcomes and peri- and postoperative outcome of elective sigmoidectomy for chronic diverticular disease, and compare it to conservatively treated patients.

Conditions

  • Diverticulitis Colon
  • Quality of Life
  • Diverticular Disease of Left Side of Colon

Interventions

PROCEDURE

Sigmoidectomy

Conventional laparoscopic resection of the sigmoid colon

DIETARY_SUPPLEMENT

Conservative

According to current practice including advice on supplementary dietary fiber, analgetics, or laxatives when indicated.

Sponsors & Collaborators

  • Randers Regional Hospital

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Helene R Dalby, MD · Randers Regional Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-22
Primary Completion
2026-10-31
Completion
2027-12-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05393609 on ClinicalTrials.gov