Clinical Trials

NCT04801797 | ACTIVE_NOT_RECRUITING | PHASE2

172 participants

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-05-20

Completion:

2027-01-01

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04797364 | ACTIVE_NOT_RECRUITING | NA

6000 participants

Pharmacogenetic Supported Prescribing in Kids

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-01-18

Completion:

2026-10-01

Conditions

• Mental Health Impairment

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04746924 | TERMINATED | PHASE3

669 participants

A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-05-24

Completion:

2025-05-30

Conditions

• Non-small Cell Lung Cancer
• NSCLC

Interventions

• DRUG

Results Available

NCT04743856 | COMPLETED | NA

54 participants

The Clinical Referral to Activity Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2022-03-29

Completion:

2024-09-30

Conditions

• Physical Inactivity
• Cardiovascular Risk Factor
• Obesity
• Blood Pressure
• PreDiabetes

Interventions

• BEHAVIORAL

Results Available

NCT04743674 | RECRUITING

30 participants

Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2024-05-03

Completion:

2027-01-15

Conditions

• Cervical Cancer

No Results Yet

NCT04739761 | ACTIVE_NOT_RECRUITING | PHASE3

506 participants

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-06-22

Completion:

2024-02-08

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT04731844 | COMPLETED | PHASE2

30 participants

Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-12-14

Completion:

2024-09-19

Conditions

• Prostate Cancer
• Multiple Myeloma
• Smoldering Multiple Myeloma (SMM)
• Monoclonal Gammopathy of Undetermined Significance

Interventions

• DRUG

Results Available

NCT04699799 | RECRUITING | NA

100 participants

Characterization of Human Olfactory Amygdala Subregions

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2022-01-01

Completion:

2027-04-01

Conditions

• Human Olfactory Amygdala

Interventions

• OTHER

No Results Yet

NCT04659850 | COMPLETED | NA

24 participants

Impact of AGEs on Metabolism & Cognition

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-11-01

Completion:

2022-03-31

Conditions

• No Conditions

Interventions

• OTHER

No Results Yet

NCT04654468 | ACTIVE_NOT_RECRUITING | PHASE3

51 participants

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-03-17

Completion:

2022-02-10

Conditions

• Paroxysmal Nocturnal Hemoglobinuria

Interventions

• DRUG

Results Available

NCT04619056 | COMPLETED | PHASE1

21 participants

First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-06-03

Completion:

2025-11-28

Conditions

• Locally Advanced Soft Tissue Sarcoma
• Recurrent Soft Tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT04605926 | WITHDRAWN | PHASE3

0 participants

A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-11-30

Completion:

2021-04-30

Conditions

• Coronavirus

Interventions

• BIOLOGICAL

No Results Yet

NCT04595773 | ACTIVE_NOT_RECRUITING | NA

48 participants

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-01-22

Completion:

2025-05-05

Conditions

• COVID-19

Interventions

• OTHER

Results Available

NCT04545736 | RECRUITING | PHASE1/PHASE2

56 participants

Oral Metformin for Treatment of ABCA4 Retinopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-11-23

Completion:

2028-09-30

Conditions

• ABCA4 Retinopathy
• Stargardt Disease
• Retinal Dystrophy
• Retinal Degeneration

Interventions

• DRUG

No Results Yet

NCT04533529 | COMPLETED | PHASE3

588 participants

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-09-16

Completion:

2023-04-25

Conditions

• Depressive Disorder, Major

Interventions

• DRUG

Results Available

NCT04529785 | RECRUITING | NA

100 participants

Added Value of Vein of Marshal Ethanol Infusion Compared to Superior Vena Cava Isolation Alone in Patients Undergoing Repeat Ablation for Recurrent Paroxysmal Atrial Fibrillation Despite Durable PV Isolation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-09-11

Completion:

2027-12-31

Conditions

• Paroxysmal Atrial Fibrillation

Interventions

• PROCEDURE

No Results Yet

NCT04507581 | COMPLETED

30 participants

Evaluation of Atelectasis Formation With Electrical Impedance Tomography During Anesthesia for MRI in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2020-07-30

Completion:

2024-10-30

Conditions

• Anesthesia

Interventions

• OTHER

No Results Yet

NCT04429087 | RECRUITING | PHASE1

300 participants

A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-07-29

Completion:

2026-09-01

Conditions

• Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Interventions

• DRUG

No Results Yet

NCT04407754 | ACTIVE_NOT_RECRUITING | NA

168 participants

Myo-Inositol for Infertility in PCOS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2022-02-07

Completion:

2026-12-31

Conditions

• Polycystic Ovary Syndrome

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04394806 | RECRUITING

140 participants

The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2022-03-01

Completion:

2027-07-31

Conditions

• Pregnancy

No Results Yet

NCT04356495 | COMPLETED | PHASE2/PHASE3

412 participants

Trial of COVID-19 Outpatient Treatment in Individuals With Risk Factors for Aggravation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-07-29

Completion:

2021-10-08

Conditions

• Corona Virus Infection
• Sars-CoV2

Interventions

• DIETARY_SUPPLEMENT
• DRUG

No Results Yet

NCT04354246 | COMPLETED | PHASE1

94 participants

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-03-31

Completion:

2026-04-01

Conditions

• Advanced Cancer
• Ovarian Cancer
• Lung Cancer
• Colon Cancer
• Plasma Cell Neoplasm
• Multiple Myeloma
• HNSCC
• Microsatellite Stable Colorectal Carcinoma
• MSS-CRC

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT04338893 | COMPLETED | NA

252 participants

ROSA Total Knee Post Market Study EMEA

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-12-15

Completion:

2025-08-22

Conditions

• Knee Pain
• Chronic Osteoarthritis
• Avascular Necrosis of the Femoral Condyle
• Moderate Varus, Valgus or Flexion Deformities
• Rheumatoid Arthritis

Interventions

• PROCEDURE

Results Available

NCT04309565 | COMPLETED | NA

398 participants

Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-04-21

Completion:

2025-10-30

Conditions

• Opioid Addiction

Interventions

• BEHAVIORAL

No Results Yet

NCT04290741 | COMPLETED | NA

599 participants

Emergency Department Acupuncture for Acute Musculoskeletal Pain Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-02-10

Completion:

2023-04-19

Conditions

• Musculoskeletal Pain

Interventions

• PROCEDURE

No Results Yet

NCT04276532 | ACTIVE_NOT_RECRUITING | NA

780 participants

Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-02-13

Completion:

2027-01-26

Conditions

• Middle-high Risk Endometrial Cancer
• Sentinel Lymph Node Sampling
• Prognosis

Interventions

• PROCEDURE

No Results Yet

NCT04263480 | ACTIVE_NOT_RECRUITING | PHASE2

99 participants

Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's Macroglobulinemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-08-18

Completion:

2028-05-31

Conditions

• Waldenstrom Macroglobulinemia

Interventions

• DRUG

No Results Yet

NCT04261192 | RECRUITING

120 participants

Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative Therapies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2020-07-03

Completion:

2027-02-28

Conditions

• Head and Neck Cancer

Interventions

• OTHER

No Results Yet

NCT04257929 | COMPLETED | PHASE2

65 participants

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-12-09

Completion:

2022-08-17

Conditions

• Prader-Willi Syndrome

Interventions

• DRUG

Results Available

NCT04245085 | COMPLETED | PHASE2

95 participants

ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-09-29

Completion:

2024-07-22

Conditions

• EGFRmutant Stage IIIB/C or IV Non-squamous NSCLC

Interventions

• DRUG

Results Available

NCT04238299 | ACTIVE_NOT_RECRUITING

486 participants

Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2021-06-01

Completion:

2027-02-28

Conditions

• Chronic Kidney Diseases

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04207723 | COMPLETED | NA

120 participants

Transcutaneous Posterior Tibial Nerve Stimulation for Premature Ejaculation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-07-15

Completion:

2026-01-09

Conditions

• Premature Ejaculation

Interventions

• OTHER
• DRUG

No Results Yet

NCT04205409 | COMPLETED | PHASE2

20 participants

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-06-05

Completion:

2024-09-20

Conditions

• Recurrent Chronic Lymphocytic Leukemia
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Follicular Lymphoma
• Recurrent Grade 1 Follicular Lymphoma
• Recurrent Grade 2 Follicular Lymphoma
• Recurrent Grade 3 Follicular Lymphoma
• Recurrent Grade 3a Follicular Lymphoma
• Recurrent Marginal Zone Lymphoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Plasma Cell Myeloma
• Refractory Chronic Lymphocytic Leukemia
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Marginal Zone Lymphoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Plasma Cell Myeloma
• Recurrent Mantle Cell Lymphoma
• Refractory Mantle Cell Lymphoma

Interventions

• BIOLOGICAL

Results Available

NCT04200937 | ENROLLING_BY_INVITATION

450 participants

IT Matters: The Erectile Restoration Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2021-08-05

Completion:

2031-01-31

Conditions

• Erectile Dysfunction

Interventions

• DEVICE

No Results Yet

NCT04161248 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

40 participants

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2020-09-02

Completion:

2026-12-31

Conditions

• Lymphoma, B-Cell

Interventions

• DRUG

No Results Yet

NCT04150887 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2019-12-23

Completion:

2027-05-15

Conditions

• Leukemia, Myeloid, Acute

Interventions

• DRUG

No Results Yet

NCT04144907 | RECRUITING | NA

40 participants

Protein Needs Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2021-04-26

Completion:

2030-09-30

Conditions

• Colorectal Cancer
• Breast Cancer

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04106856 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Pancreatic Cancer (SHAPER)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2019-08-08

Completion:

2024-12-06

Conditions

• Borderline Resectable Pancreatic Adenocarcinoma
• Locally Advanced Pancreatic Ductal Adenocarcinoma
• Locally Advanced Unresectable Pancreatic Adenocarcinoma
• Stage II Pancreatic Cancer AJCC v8
• Stage IIA Pancreatic Cancer AJCC v8
• Stage IIB Pancreatic Cancer AJCC v8
• Stage III Pancreatic Cancer AJCC v8

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04042558 | COMPLETED | PHASE2

150 participants

A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2019-09-26

Completion:

2021-10-22

Conditions

• NSCLC Stage IIIB
• NSCLC Stage IV
• EGFR Gene Mutation
• ALK Gene Rearrangement Positive
• ROS1 Gene Mutation

Interventions

• DRUG

Results Available

NCT04025515 | SUSPENDED

500 participants

Molecular Profiling Project

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2019-01-11

Completion:

2026-12-25

Conditions

• Lung Cancer
• Non-Small Cell Lung Cancer

No Results Yet