Clinical Trials

NCT03307980 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Long-term Safety and Efficacy Study and Dose-Escalation Substudy of PF 06838435 in Individuals With Hemophilia B

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-06-22

Completion:

2029-05-29

Conditions

• Hemophilia B

Interventions

• BIOLOGICAL

No Results Yet

NCT03299426 | ACTIVE_NOT_RECRUITING | PHASE3

30000 participants

Clinical Efficacy of Typhoid Conjugate Vaccine (Vi-TCV) Among Children Age 9 Months Through 12 Years in Blantyre, Malawi

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2018-02-21

Completion:

2025-01-30

Conditions

• Typhoid

Interventions

• BIOLOGICAL

No Results Yet

NCT03279094 | RECRUITING | PHASE1

11 participants

Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2018-02-02

Completion:

2027-01-25

Conditions

• Sickle Cell Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT03271372 | ACTIVE_NOT_RECRUITING | PHASE3

101 participants

Adjuvant Avelumab in Merkel Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-12-19

Completion:

2026-04-03

Conditions

• Stage III Merkel Cell Carcinoma AJCC v8
• Stage IIIB Merkel Cell Carcinoma AJCC v8
• Stage IIIA Merkel Cell Carcinoma AJCC v8

Interventions

• DRUG
• OTHER

No Results Yet

NCT03191656 | ACTIVE_NOT_RECRUITING

500 participants

REDUCE LAP-HF III Corvia Protocol 1701

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2017-03-12

Completion:

2026-07-31

Conditions

• Heart Failure

Interventions

• DEVICE

No Results Yet

NCT03078491 | COMPLETED | NA

168 participants

Technological Advances in Glucose Management in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-03-30

Completion:

2022-09-01

Conditions

• Type 1 Diabetes Mellitus
• Older Adults
• Hypoglycemia

Interventions

• OTHER

No Results Yet

NCT03073941 | ACTIVE_NOT_RECRUITING | NA

332 participants

A Multicenter Prospective Randomized Control Study on Persona Total Knee System vs NexGen

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-12-31

Completion:

2021-11-23

Conditions

• Osteoarthritis, Knee

Interventions

• DEVICE

Results Available

NCT03061786 | WITHDRAWN

0 participants

Prognosis of Acute Kidney Injury:China Collaborative Study on AKI（CCS-AKI）Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2017-01-31

Completion:

2019-12-31

Conditions

• Acute Kidney Injury

No Results Yet

NCT03061006 | COMPLETED | PHASE4

101 participants

Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-03-30

Completion:

2021-03-15

Conditions

• Dementia
• Cognition Disorders
• Cerebral Ischemic Events

Interventions

• DRUG

Results Available

NCT03049410 | COMPLETED | NA

339 participants

Trial to Compare Robotically Assisted Radical Cystectomy With Open Radical Cystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-03-01

Completion:

2021-09-30

Conditions

• Bladder Cancer

Interventions

• PROCEDURE

No Results Yet

NCT03047135 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-03-01

Completion:

2023-05-24

Conditions

• Prostate

Interventions

• DRUG

Results Available

NCT03038672 | ACTIVE_NOT_RECRUITING | PHASE2

54 participants

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2018-12-21

Completion:

2023-05-26

Conditions

• ALK-Positive Large B-Cell Lymphoma
• Diffuse Large B-Cell Lymphoma Activated B-Cell Type
• Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation
• Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
• Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• EBV-Positive Mucocutaneous Ulcer
• HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements
• High Grade B-Cell Lymphoma, Not Otherwise Specified
• Intravascular Large B-Cell Lymphoma
• Large B-Cell Lymphoma With 11q Aberration
• Large B-Cell Lymphoma With IRF4 Rearrangement
• Plasmablastic Lymphoma
• Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
• Primary Effusion Lymphoma
• Recurrent B-Cell Non-Hodgkin Lymphoma
• Recurrent Burkitt Lymphoma
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Gray-Zone Lymphoma
• Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
• Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
• Recurrent Lymphomatoid Granulomatosis
• Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
• Recurrent Primary Mediastinal Large B-Cell Lymphoma
• Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
• Refractory B-Cell Non-Hodgkin Lymphoma
• Refractory Burkitt Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Gray-Zone Lymphoma
• Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
• Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
• Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
• Refractory Primary Mediastinal Large B-Cell Lymphoma
• Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03017807 | COMPLETED | PHASE1

18 participants

Safety and Pharmacokinetics of Recombinant Anti-EGFr Antibody in Patients With Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-12-30

Completion:

2018-01-22

Conditions

• Metastatic Colorectal Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT02998567 | ACTIVE_NOT_RECRUITING | PHASE1

60 participants

Combination Study of Guadecitabine/ASTX727 and Pembrolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-01-26

Completion:

2026-09-30

Conditions

• Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT02986386 | COMPLETED | NA

150 participants

Oral Health for Healthy Cognitive Aging

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-11-30

Completion:

2023-01-31

Conditions

• Malocclusion
• Dementia

Interventions

• PROCEDURE

No Results Yet

NCT02969447 | COMPLETED | PHASE4

27 participants

Management of Third-stage of Labor After Second Trimester Medical Pregnancy Termination

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-10-20

Completion:

2017-08-04

Conditions

• Retained Placenta

Interventions

• DRUG

No Results Yet

NCT02935400 | ACTIVE_NOT_RECRUITING

50 participants

Acute Porphyria Biomarkers for Disease Activity

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2014-04-28

Completion:

2026-12-31

Conditions

• Acute Intermittent Porphyria
• Hereditary Coproporphyria
• Variegate Porphyria

Interventions

• DRUG

No Results Yet

NCT02926911 | ACTIVE_NOT_RECRUITING | NA

997 participants

Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-02-22

Completion:

2024-06-27

Conditions

• DCIS
• Ductal Carcinoma in Situ

Interventions

• OTHER

Results Available

NCT02830308 | RECRUITING

1250 participants

Evaluation of Adults With Endocrine and Metabolic-Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2016-07-09

Completion:

2029-12-20

Conditions

• Endocrine Diseases

No Results Yet

NCT02821013 | RECRUITING | PHASE3

614 participants

Duration of Anti-PD-1 Therapy in Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-10-31

Completion:

2027-12-31

Conditions

• Unresectable/Metastatic Melanoma

Interventions

• DRUG

No Results Yet

NCT02817789 | COMPLETED | PHASE3

50 participants

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-05-09

Completion:

2018-05-30

Conditions

• Aortic Valve Stenosis

Interventions

• DRUG

No Results Yet

NCT02774694 | SUSPENDED

350 participants

Prediction of Outcome of Interventional Pain Management

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2026-06-30

Completion:

2027-09-30

Conditions

• Low Back Pain
• Neck Pain
• Chronic Pain

Interventions

• DEVICE

No Results Yet

NCT02761889 | COMPLETED | NA

444 participants

Hypofractionated Image-Guided Radiotherapy (IGRT) With Organ Motion Mitigation and Urethral Sparing for Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2013-05-01

Completion:

2025-12-30

Conditions

• Adenocarcinoma of the Prostate

Interventions

• RADIATION
• DEVICE

No Results Yet

NCT02720458 | COMPLETED | NA

62 participants

Self Help Program for Hypnotics Withdrawal in Insomniac Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-10-04

Completion:

2019-10-25

Conditions

• Insomnia

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT02692885 | RECRUITING

300 participants

Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2016-03-22

Completion:

2026-10-31

Conditions

• Brown Adipose Tissue (BAT) Physiology
• Phenotyping
• Brown Adipocytes

No Results Yet

NCT02689427 | COMPLETED | PHASE2

24 participants

Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-09-22

Completion:

2023-11-15

Conditions

• Invasive Breast Carcinoma
• Stage I Breast Cancer AJCC v7
• Stage IA Breast Cancer AJCC v7
• Stage IB Breast Cancer AJCC v7
• Stage II Breast Cancer AJCC v6 and v7
• Stage IIA Breast Cancer AJCC v6 and v7
• Stage IIB Breast Cancer AJCC v6 and v7
• Stage III Breast Cancer AJCC v7
• Stage IIIA Breast Cancer AJCC v7
• Stage IIIB Breast Cancer AJCC v7
• Stage IIIC Breast Cancer AJCC v7
• Triple-Negative Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT02629042 | COMPLETED | PHASE3

5 participants

Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2017-05-15

Completion:

2018-11-28

Conditions

• Pulpitis

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT02613650 | COMPLETED | PHASE1

25 participants

A Trial of mFOLFIRI With MEK162 in Patients With Advanced RAS (HRAS, NRAS, or KRAS) Positive Metastatic Colorectal Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-08-19

Completion:

2022-11-23

Conditions

• Advanced KRAS Positive Metastatic Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT02604563 | RECRUITING

2000 participants

Aging, Geriatric Syndromes and Clonal Hematopoiesis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-12

Start Date:

2016-03-10

Completion:

2030-04-30

Conditions

• Geriatrics
• Aged
• Geriatric Syndromes
• Cardiovascular Diseases

Interventions

• OTHER
• GENETIC
• PROCEDURE

No Results Yet

NCT02562235 | ACTIVE_NOT_RECRUITING | PHASE3

24 participants

Riociguat in Children With Pulmonary Arterial Hypertension (PAH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-10-29

Completion:

2020-03-07

Conditions

• Hypertension, Pulmonary

Interventions

• DRUG

Results Available

NCT02466984 | COMPLETED | PHASE3

5 participants

Subcutaneous Route and Pharmacology of Metoclopramide

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2016-07-31

Completion:

2018-02-08

Conditions

• Nausea
• Vomiting

Interventions

• DRUG

No Results Yet

NCT02453282 | ACTIVE_NOT_RECRUITING | PHASE3

1118 participants

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-07-21

Completion:

2018-10-04

Conditions

• Non-Small-Cell Lung Carcinoma NSCLC

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT02437227 | COMPLETED | PHASE1

31 participants

Dose Escalation Study With Expansion to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of CCT3833

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-04-15

Completion:

2017-12-31

Conditions

• Melanoma
• Cancer

Interventions

• DRUG

Results Available

NCT02333110 | RECRUITING | NA

50 participants

GRID Therapy as Palliative Radiation for Patients With Advanced and Symptomatic Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-01-31

Completion:

2026-12-31

Conditions

• Patients With Symptomatic or Bulky Tumors (More Than 8 cm) or With Tumors Resistant to Radiation

Interventions

• RADIATION

No Results Yet

NCT02329262 | COMPLETED | NA

571 participants

A Skills-based RCT for Physical Activity Using Peer Mentors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-09-30

Completion:

2018-11-01

Conditions

• Health Behavior
• Obesity
• Motor Activity

Interventions

• BEHAVIORAL

Results Available

NCT02320435 | ACTIVE_NOT_RECRUITING | PHASE3

154 participants

A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2015-02-02

Completion:

2026-12-31

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT02308527 | COMPLETED | PHASE2

225 participants

Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2013-07-31

Completion:

2021-08-01

Conditions

• Neuroblastoma

Interventions

• DRUG

No Results Yet

NCT02266719 | ENROLLING_BY_INVITATION | NA

750 participants

Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2014-12-01

Completion:

2028-12-31

Conditions

• Aortic Aneurysm, Abdominal
• Thoracic Aneurysm

Interventions

• DEVICE

No Results Yet

NCT02264678 | ACTIVE_NOT_RECRUITING | PHASE1

354 participants

Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2014-10-31

Completion:

2025-03-04

Conditions

• Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT02262832 | ACTIVE_NOT_RECRUITING | PHASE3

24 participants

Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-12

Start Date:

2014-10-09

Completion:

2027-07-31

Conditions

• Lipodystrophy
• Diabetes
• Hyperlipidemia

Interventions

• DRUG

No Results Yet