Clinical Trials Updated in 2025

NCT07292363 | COMPLETED

45 participants

Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-02-09
Completion:: 2022-04-30

Conditions

Apical Periodontitis
Healhty

Interventions

OTHER

No Results Yet

NCT07288008 | RECRUITING | NA

40 participants

Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-15
Completion:: 2027-12-30

Conditions

Anxiety

Interventions

DEVICE

No Results Yet

NCT07287748 | RECRUITING | PHASE1

38 participants

A Phase I Trial of Af-001 in Patients With Differentiated Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-01-01
Completion:: 2028-07-31

Conditions

DTC - Differentiated Thyroid Cancer

Interventions

DRUG

No Results Yet

NCT07286981 | COMPLETED | NA

40 participants

Glycemic Index of Date Cultivars and Date-based Products

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-08-16
Completion:: 2025-05-25

Conditions

Glycaemic Response Measurements

Interventions

OTHER

No Results Yet

NCT07286799 | COMPLETED

54 participants

Comparison of the Analgesic Efficacy of Transversalis Fascia Plane Block and Posterior Quadratus Lumborum Block in Pediatric Patient Undergoing Orchiopexy: A Prospective Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-05-01
Completion:: 2025-11-01

Conditions

Pain Management
Orchiopexy
Transversalis Fascia Plane Block
Quadratus Lumborum Block

No Results Yet

NCT07283133 | COMPLETED | NA

34 participants

Effects of Task Specific Circuit Training on Gross Motor Function, Balance, and Quality of Life in Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-13
Completion:: 2025-12-10

Conditions

Cerebral Palsy (CP)
Quality of Life (QOL)

Interventions

PROCEDURE

No Results Yet

NCT07275229 | NOT_YET_RECRUITING | NA

62 participants

Efficacy and Safety of Irregular Pulsed Radiofrequency (Sluijter-Teixera Poisson) Versus Regular Pulsed Radiofrequency to the Gasserian Ganglion for Treatment of Primary Trigeminal Neuralgia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Trigeminal Neuralgia

Interventions

PROCEDURE

No Results Yet

NCT07274995 | ACTIVE_NOT_RECRUITING

90 participants

Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-01
Completion:: 2026-11-30

Conditions

Pain, Acute Post-Operative
Ambulatory Surgical Procedures
Pediatric Pain
Pediatric Patient (1m-21y)

No Results Yet

NCT07268196 | RECRUITING

100 participants

Impact of Liver Transplantation on Sexual Life and Function

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-07
Completion:: 2026-10-23

Conditions

Chronic Liver Disease and Cirrhosis

Interventions

OTHER

No Results Yet

NCT07263919 | RECRUITING | PHASE2

90 participants

Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-19
Completion:: 2030-03-31

Conditions

Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07263061 | RECRUITING

1000 participants

Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary Surgeries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-07
Completion:: 2026-10-23

Conditions

Hepatobiliary Disease
Pancreas Disease
Bile Duct Diseases

Interventions

OTHER

No Results Yet

NCT07253324 | COMPLETED | PHASE1

48 participants

ENX-104 MAD Study for Participants With Major Depressive Disorder With Anhedonia (aMDD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-02-17
Completion:: 2025-11-26

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT07251998 | RECRUITING | PHASE2

172 participants

Efficacy and Safety of ICP-332 Versus Placebo in Participants With Moderate to Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-22
Completion:: 2026-10-31

Conditions

Plaque Psoriasis

Interventions

DRUG
OTHER

No Results Yet

NCT07248995 | RECRUITING | NA

30 participants

Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-01
Completion:: 2027-05-31

Conditions

Acute Respiratory Distress Syndrome (ARDS)
Acute Brain Injury

Interventions

PROCEDURE

No Results Yet

NCT07238816 | RECRUITING | PHASE1

80 participants

A Research Study Looking at How Food Intake Affects Inno8 in the Body of Healthy People

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-11-18
Completion:: 2026-04-29

Conditions

Haemophilia A

Interventions

DRUG

No Results Yet

NCT07235202 | RECRUITING | PHASE1/PHASE2

45 participants

A Study of MR001 Combined With Chemotherapy in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) After First-line Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-24
Completion:: 2028-06-22

Conditions

Pancreatic Ductal Adenocarcinoma (PDAC)

Interventions

DRUG

No Results Yet

NCT07232524 | RECRUITING | PHASE1

16 participants

A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-10
Completion:: 2027-11-30

Conditions

Head and Neck Squamous Cell Carcinoma
Solid Tumor

Interventions

DRUG

No Results Yet

NCT07232238 | ACTIVE_NOT_RECRUITING

60 participants

TRPM2 Gene Polymorphism, NLRP3 Inflammasome Expression in Vitiligo Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-10-20
Completion:: 2026-10-01

Conditions

Vitiligo

No Results Yet

NCT07224880 | RECRUITING

10 participants

Ellacor® Micro-Coring Technology® in Fitzpatrick Skin Types I-VI, Including Patients Receiving Glucagon-Like Peptide-1 Receptor Agonists

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-10-14
Completion:: 2026-01-30

Conditions

glp1 Agonist
Gene Expression
Skin Laxity

Interventions

DEVICE

No Results Yet

NCT07224438 | RECRUITING | PHASE2

20 participants

Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-09
Completion:: 2030-05-31

Conditions

Hypothalamic Amenorrhea
Hypogonadotropic Hypogonadism

Interventions

DRUG

No Results Yet

NCT07206940 | ACTIVE_NOT_RECRUITING | NA

38 participants

Study of the Benefits of Virtual Reality Headsets for Reducing Anxiety in Patients Treated for Pleural Effusion or Pneumothorax Using Small-bore Chest Drainage Tubes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-11-27
Completion:: 2027-05-31

Conditions

Pneumothorax
Pleural Effusion
Drainage of Liquor

Interventions

DEVICE

No Results Yet

NCT07203755 | RECRUITING | PHASE1

260 participants

Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-19
Completion:: 2029-02-28

Conditions

Diphtheria, Tetanus and Acellular Pertussis
Epidemic Meningitis
Haemophilus Influenzae Type B Infection

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07203196 | ACTIVE_NOT_RECRUITING | NA

16 participants

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-10-22
Completion:: 2026-04-01

Conditions

Aging, Healthy
Blood Sugar; High
Blood Sugar (Glucose) Control
Time Restricted Eating
Circadian Dysregulation

Interventions

BEHAVIORAL

No Results Yet

NCT07200986 | ACTIVE_NOT_RECRUITING | PHASE1

218 participants

Study to Compare Pharmacokinetics and Safety of CT-P52 and US-licensed Taltz in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-17
Completion:: 2026-03-31

Conditions

Healthy Participants

Interventions

BIOLOGICAL

No Results Yet

NCT07193056 | NOT_YET_RECRUITING

1000 participants

The CPH-MBD Cohort

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-31
Completion:: 2055-01-31

Conditions

Chronic Kidney Disease Mineral and Bone Disorder
Chronic Kidney Disease (CKD)
Bone Markers

No Results Yet

NCT07189624 | NOT_YET_RECRUITING | NA

12 participants

Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-31
Completion:: 2028-04-30

Conditions

Cirrhosis With Hepatocellular Carcinoma

Interventions

OTHER

No Results Yet

NCT07170319 | ACTIVE_NOT_RECRUITING | PHASE1

79 participants

A Study of IBI3032 in Chinese Participants With Overweight or Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-25
Completion:: 2025-12-24

Conditions

Overweight or Obesity

Interventions

DRUG

No Results Yet

NCT07167797 | COMPLETED | NA

60 participants

Evaluation of the Role of Vitamin D in Reducing the Severity and Duration of Rotavirus Infection in Iraqi Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-01-01
Completion:: 2025-05-01

Conditions

Rotaviral Gastroenteritis

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT07154303 | ENROLLING_BY_INVITATION

209 participants

Testing the Performance of Smartphones and Their Accessories in Detecting Irregularly Irregular Heart Rhythm

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-27
Completion:: 2026-08-31

Conditions

Atrial Fibrillation (AF)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07154173 | RECRUITING

300 participants

Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-01-01
Completion:: 2026-12-31

Conditions

Rectal Neoplasms
Colon Neoplasms
Microbiota
Metagenome

Interventions

PROCEDURE

No Results Yet

NCT07149610 | RECRUITING | NA

388 participants

Connected Care for Type 2 Diabetes Self-Management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-10-13
Completion:: 2026-11-30

Conditions

Diabetes Type 2

Interventions

DEVICE

No Results Yet

NCT07148115 | RECRUITING

50 participants

Pregnancies Before the Diagnosis of Systemic Lupus Erythematosus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-01-01
Completion:: 2025-12-31

Conditions

Pregnancy Complications
SLE

Interventions

OTHER

No Results Yet

NCT07147634 | RECRUITING | NA

1000 participants

Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-02
Completion:: 2026-11-30

Conditions

Healthy Children

Interventions

BEHAVIORAL

No Results Yet

NCT07139951 | ENROLLING_BY_INVITATION | PHASE2

16 participants

Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-12-03
Completion:: 2027-05-03

Conditions

Clinical Stage I Gastric Cancer AJCC v8
Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage II Gastric Cancer AJCC v8
Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07135856 | RECRUITING

400 participants

Sleeve Lobectomy Following Neoadjuvant Therapy in NSCLC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-09-01
Completion:: 2025-11-01

Conditions

Lung Cancer
Neoadjuvant Therapy

No Results Yet

NCT07134478 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Clinical Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of HSK31858 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-10-28
Completion:: 2024-12-24

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT07134465 | ENROLLING_BY_INVITATION | PHASE1

24 participants

Clinical Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of HSK31858 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-11
Completion:: 2026-11-30

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT07133178 | WITHDRAWN | PHASE3

0 participants

A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2026-02-06
Completion:: 2026-12-31

Conditions

Chikungunya Virus Infection

Interventions

BIOLOGICAL

No Results Yet

NCT07124689 | COMPLETED

87 participants

Relationship Between Central Sensitization Levels and Treatment Outcomes in Frozen Shoulder Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-09
Completion:: 2025-11-15

Conditions

Treatment
Intra-Articular Injection
Frozen Shoulder
Central Sensitisation
Shoulder Pain

Interventions

OTHER

No Results Yet

NCT07100041 | COMPLETED | NA

210 participants

Use of Breathing Exercises and Stress Balls During Dressing Changes in Burn Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2025-08-04
Completion:: 2025-12-02

Conditions

Anxiety
Breathing Exercise
Burns (Physical Finding)
Pain
Pain Management
Stress Ball

Interventions

OTHER

No Results Yet