Clinical Trials Updated in 2025

NCT05909917 | COMPLETED | NA

658 participants

Deploying Emergency Bystander Internet Training

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-07-15
Completion:: 2024-08-31

Conditions

Trauma
Trauma Injury

Interventions

OTHER

No Results Yet

NCT05904886 | ACTIVE_NOT_RECRUITING | PHASE3

687 participants

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-09-14
Completion:: 2025-05-08

Conditions

Hepatocellular Carcinoma

Interventions

DRUG
OTHER

No Results Yet

NCT05866718 | COMPLETED | NA

497 participants

Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-06-14
Completion:: 2024-09-22

Conditions

Psychopathology

Interventions

BEHAVIORAL

No Results Yet

NCT05858229 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Neo-adjuvant Treatment for Squamous Cell Carcinoma Using Direct Tumor Injection With RP1.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-06-16
Completion:: 2025-12-31

Conditions

Squamous Cell Carcinoma
RP1

Interventions

DRUG

No Results Yet

NCT05845489 | RECRUITING | PHASE4

11086 participants

Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- CloPidogREl for Primary preVENTION (HOST-PREVENTION)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-03-22
Completion:: 2028-12-31

Conditions

Coronary Artery Disease

Interventions

DRUG
OTHER

No Results Yet

NCT05800977 | RECRUITING | PHASE1/PHASE2

112 participants

A Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-02-22
Completion:: 2027-03-31

Conditions

Relapsed/Refractory Large B-Cell Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT05791526 | COMPLETED

308 participants

An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-12-19
Completion:: 2025-12-09

Conditions

Ulcerative Colitis

No Results Yet

NCT05749874 | ACTIVE_NOT_RECRUITING | PHASE4

2024 participants

Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-10-31
Completion:: 2026-12-31

Conditions

PreDiabetes
Abdominal Obesity
Hypertension
Dyslipidemias
Atherosclerotic Cardiovascular Disease

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT05746806 | ACTIVE_NOT_RECRUITING | NA

36 participants

Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-03-29
Completion:: 2027-11-30

Conditions

Recurrent Prostate Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT05717166 | RECRUITING | PHASE3

180 participants

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-10-06
Completion:: 2029-04-30

Conditions

Metastatic Tumor

Interventions

RADIATION
DRUG
OTHER
PROCEDURE

No Results Yet

NCT05691647 | RECRUITING | NA

76 participants

Chronotherapy for Depressive Episodes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-04-12
Completion:: 2029-01-31

Conditions

Depressive Episode

Interventions

BEHAVIORAL

No Results Yet

NCT05659966 | ACTIVE_NOT_RECRUITING | NA

228 participants

Nutritious Eating With Soul Dissemination and Implementation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-04-03
Completion:: 2027-03-31

Conditions

Nutrition, Healthy
Eating Behavior

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05658445 | COMPLETED

86 participants

Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-01-01
Completion:: 2025-04-01

Conditions

Abortion, Habitual

Interventions

OTHER

No Results Yet

NCT05657301 | ACTIVE_NOT_RECRUITING | PHASE1

25 participants

Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-10-16
Completion:: 2026-09-30

Conditions

Age-Related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT05646641 | COMPLETED | NA

57 participants

Strength Training in Fibromyalgia on Balance, Neuromuscular Performance and Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-10-05
Completion:: 2025-08-07

Conditions

Fibromyalgia

Interventions

OTHER

No Results Yet

NCT05629026 | RECRUITING | NA

60 participants

Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-02-21
Completion:: 2026-02-28

Conditions

Lymphedema

Interventions

PROCEDURE

No Results Yet

NCT05598112 | RECRUITING | EARLY_PHASE1

210 participants

Effect of Gut Microbiome Intervention on Aging Via Oral FMT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-04-24
Completion:: 2026-12-31

Conditions

Aging
Frailty

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05589688 | RECRUITING | PHASE1

20 participants

Individualization of Dosage Regimens in Obese Patients: Application to Acyclovir

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-04-09
Completion:: 2026-12-31

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT05559736 | WITHDRAWN | NA

0 participants

Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-05-24
Completion:: 2025-12-31

Conditions

Intertrochanteric Fractures
Femoral Fracture
Femoral Neck Fractures

Interventions

DEVICE

No Results Yet

NCT05553522 | TERMINATED | PHASE1

1 participants

Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2024-01-29
Completion:: 2025-12-17

Conditions

Brain Metastases
HER2-positive Breast Cancer

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05521256 | COMPLETED | PHASE1

70 participants

A Research Study of a New Medicine NNC0113-6856 in Healthy Males

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-08-26
Completion:: 2023-03-27

Conditions

Healthy Volunteers
Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT05514340 | RECRUITING | PHASE2

40 participants

Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-09-06
Completion:: 2026-11-30

Conditions

Hypoxic-Ischemic Encephalopathy
Neonatal Asphyxia
Neonatal Encephalopathy

Interventions

DRUG

No Results Yet

NCT05470816 | ACTIVE_NOT_RECRUITING | PHASE3

826 participants

Tranexamic Acid to Reduce Delirium After Gastrointestinal Surgery: the TRIGS-D Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-11-01
Completion:: 2026-08-13

Conditions

Surgical Site Infection
Dementia
Cognition

Interventions

DRUG

No Results Yet

NCT05468333 | COMPLETED | NA

184 participants

"Natural" and "Organic" Cigarette Descriptors: Association With Expectancies, Subjective Effects, Topography, and Biomarkers of Exposure Among Daily Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-01-20
Completion:: 2024-08-31

Conditions

Smoking Behaviors

Interventions

OTHER

No Results Yet

NCT05449301 | COMPLETED | NA

63 participants

Effects of Unilateral Step Training on Gait and Balance in Stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-01-01
Completion:: 2024-06-30

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT05427448 | COMPLETED | NA

342 participants

Validation of Blood Biomarkers for Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-11-24
Completion:: 2025-05-20

Conditions

Alzheimer Disease
Mild Cognitive Impairment
Dementia
Tauopathies

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05410548 | COMPLETED | NA

70 participants

Comorbidity Screening and Referral by Prosthetists

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-06-09
Completion:: 2023-01-30

Conditions

Limb Ischemia
Low Back Pain
Depression
Neuropathy;Peripheral
Amputation

Interventions

OTHER

No Results Yet

NCT05379829 | COMPLETED | PHASE1

24 participants

A Research Study of How the Medicine Ziltivekimab Works in the Body of Chinese Men and Women With Kidney Disease and Inflammation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-05-30
Completion:: 2024-06-12

Conditions

Chronic Kidney Disease and Systemic Inflammation

Interventions

DRUG

No Results Yet

NCT05379023 | COMPLETED | NA

116 participants

VIdeo Telehealth in ALzheimer's: NeuroPsychology (VITAL-NP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-06-27
Completion:: 2024-05-16

Conditions

Suspected Typical Alzheimer's Disease (AD)
Suspected Atypical Alzheimer's Disease (AD)

Interventions

BEHAVIORAL

Results Available

NCT05364957 | RECRUITING | NA

84 participants

Intragastric Balloon in Obese Patients With Uncontrolled Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-05-12
Completion:: 2029-07-31

Conditions

Obesity
Asthma

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT05363774 | COMPLETED | PHASE1

161 participants

A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-04-20
Completion:: 2024-04-02

Conditions

Healthy Volunteers (Diabetes Mellitus, Type 2)

Interventions

DRUG

No Results Yet

NCT05312047 | COMPLETED

609 participants

Continence After Vaginal Prolapse Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-04-04
Completion:: 2025-09-19

Conditions

Pelvic Organ Prolapse
Urinary Incontinence

Interventions

PROCEDURE

No Results Yet

NCT05307289 | RECRUITING | NA

20 participants

Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-05-25
Completion:: 2028-05-25

Conditions

Melanoma (Skin)

Interventions

OTHER

No Results Yet

NCT05304065 | RECRUITING | PHASE2

1600 participants

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-10-17
Completion:: 2026-12-31

Conditions

Self-Harm
Suicide
Suicidal

Interventions

BEHAVIORAL

No Results Yet

NCT05289466 | TERMINATED | NA

5 participants

Oncoplastic Partial Mastectomy With Intraoperative Radiation Therapy (IORT) in Early Stage Breast Cancer Patients With Prior History of Chest Wall Radiation.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-12-16
Completion:: 2024-10-23

Conditions

IORT-Intra-Operative Radiation Therapy

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT05260957 | RECRUITING | PHASE2

22 participants

CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed Aggressive Non-Hodgkin's Lymphoma (NHL).

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-12-14
Completion:: 2026-12-31

Conditions

Refractory Non-Hodgkin Lymphoma
Relapsed Non Hodgkin Lymphoma
Aggressive Non-Hodgkin Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05172011 | ACTIVE_NOT_RECRUITING

15028 participants

Understanding the Long-term Impact of COVID on Children and Families

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-03-01
Completion:: 2027-04-01

Conditions

SARS-CoV-2 Infection

No Results Yet

NCT05116514 | RECRUITING | NA

256 participants

Evaluation of the Impact of Case Manager Intervention on the 3-year Psychotic Episode Recurrence Rate in Patients Aged 16 to 30 Years With a First Psychotic Episode.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-09-27
Completion:: 2028-09-30

Conditions

Psychotic Episode

Interventions

OTHER

No Results Yet

NCT05080569 | RECRUITING | PHASE4

1008 participants

Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-03-01
Completion:: 2025-12-31

Conditions

Pregnancy Related
Fertility Issues
Luteal Phase Defect
Infertility Unexplained

Interventions

DRUG

No Results Yet

NCT05069545 | COMPLETED

411 participants

A Research Study Looking at How the Use of NovoPen® 6 for Treatment With Tresiba® & Fiasp® Affects the Blood Sugar Level in Patients With Type 1 Diabetes as Part of Local Clinical Practice

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-10-11
Completion:: 2024-09-10

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet