Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage
NCT05658445 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 86
Last updated 2025-12-31
Summary
The definition of recurrent spontaneous abortion (RSA) has changed over the years, and most societies now advocate defining RSA as two or three consecutive or discontinuous miscarriages with the same sexual partner before 24 weeks gestation
In recent years, the incidence of this disease has been on the rise, occurring in about 1%- 5% of pregnancy in women at childbearing age, and the success rate of second pregnancy in RSA females has been significantly reduced The etiology of RSA is extremely complex, including anatomical factors, genetic factors, endocrine factors, infectious and immune factors, and pre-thrombosis etiology.
However, the cause of the disease is unclear in half of patients and known as unexplained recurrent spontaneous abortion (URSA)
Conditions
- Abortion, Habitual
Interventions
- OTHER
-
evacuation
after complete evacuation of uterus follow abortion
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Min Age
- 20 Years
- Max Age
- 30 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-01-01
- Primary Completion
- 2025-04-01
- Completion
- 2025-06-01
Countries
- Egypt
Study Locations
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