Clinical Trials Updated in 2025

NCT04994756 | RECRUITING

40000 participants

Stroke Thrombectomy and Aneurysm Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-09-17
Completion:: 2055-01-01

Conditions

Stroke
Thromboses, Intracranial
Aneurysm, Brain

Interventions

PROCEDURE

No Results Yet

NCT04968340 | COMPLETED | NA

600 participants

External Pop Out cs vs Conventional Method for Fetal Head Extraction in Repeatedcaesarean Section.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-06-16
Completion:: 2022-07-24

Conditions

EPO Teqnique in Fetal Head Extraction

Interventions

PROCEDURE

No Results Yet

NCT04961697 | COMPLETED | NA

431 participants

Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-12-20
Completion:: 2021-12-16

Conditions

Post-Intensive Care Syndrome
Anxiety
Depression
Stress Disorders, Post-Traumatic
Quality of Life
Satisfaction, Patient

Interventions

BEHAVIORAL

No Results Yet

NCT04946201 | SUSPENDED

60 participants

Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-09-02
Completion:: 2026-12-31

Conditions

Obstructive Sleep Apnea
Malocclusion

No Results Yet

NCT04922814 | COMPLETED | NA

40 participants

Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-08-01
Completion:: 2022-03-01

Conditions

COVID-19 Acute Respiratory Distress Syndrome
Sedation Complication
ICU Acquired Weakness

Interventions

DRUG

No Results Yet

NCT04916132 | RECRUITING

300 participants

Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive Factors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-08-10
Completion:: 2043-12-31

Conditions

Chronic Kidney Diseases
Albuminuria
Diabetic Kidney Disease
Diabetic Nephropathies
Diabetes type2
Molecular Sequence Variation
Kidney Biopsy

Interventions

PROCEDURE

No Results Yet

NCT04840472 | SUSPENDED | PHASE1

28 participants

Study Evaluating 111In-Panitumumab for Nodal Staging in Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-03-30
Completion:: 2027-03-31

Conditions

Head and Neck Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04813042 | ACTIVE_NOT_RECRUITING | NA

293 participants

Determining the Effectiveness of Working Out Dads to Reduce Mental Health Difficulties in Fathers of Young Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-06-24
Completion:: 2024-05-31

Conditions

Mental Health Issue

Interventions

BEHAVIORAL

No Results Yet

NCT04804787 | COMPLETED | NA

101 participants

Emotions in Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-06-23
Completion:: 2025-02-25

Conditions

Multiple Sclerosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04786574 | WITHDRAWN | PHASE3

0 participants

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2022-07-01
Completion:: 2025-12-10

Conditions

Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Interventions

DRUG

No Results Yet

NCT04769167 | COMPLETED | NA

114 participants

Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-02-01
Completion:: 2023-12-05

Conditions

Congenital Heart Disease
Viremia
Virus Diseases
Enterovirus
Enterovirus Infections
Heart Defects, Congenital
Heart Diseases
Prenatal Infection
Diabetes
Diabetes Mellitus, Type 2
Diabetes Mellitus, Type 1
Diabetes Mellitus
Pregnancy in Diabetic
Pregnancy Complications
Prenatal

Interventions

OTHER

No Results Yet

NCT04740567 | COMPLETED | NA

283 participants

Early Cognitive Intervention in Delirium

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-02-09
Completion:: 2024-11-14

Conditions

Delirium
Cognitive Decline
Dementia

Interventions

BEHAVIORAL

Results Available

NCT04699136 | COMPLETED | NA

60 participants

Cardiovascular Rehabilitation and Reeducation (CVRR) in Patients With Cardiac Pathologies and the 6-minute Stepper Test

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-01-13
Completion:: 2022-04-28

Conditions

Cardiac Disease

Interventions

OTHER

No Results Yet

NCT04696835 | RECRUITING | NA

40 participants

fNIRS in Pediatric Hearing Aids

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-09-09
Completion:: 2027-09-30

Conditions

Hearing Loss

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04682769 | COMPLETED

175 participants

Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-12-01
Completion:: 2025-01-25

Conditions

Coronary Heart Disease
Depression

Interventions

OTHER

No Results Yet

NCT04639778 | RECRUITING | NA

390 participants

Monitoring the Weight Evolution Using a Connected Scale

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-03-25
Completion:: 2026-12-31

Conditions

Bariatric Surgery
Long Term Follow-Up
Weight Regain

Interventions

OTHER

No Results Yet

NCT04620070 | COMPLETED | NA

221 participants

ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-10-15
Completion:: 2025-07-01

Conditions

Extracorporeal Membrane Oxygenation
Cardiac Arrest

Interventions

PROCEDURE

No Results Yet

NCT04592913 | ACTIVE_NOT_RECRUITING | PHASE3

957 participants

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-11-17
Completion:: 2024-12-20

Conditions

Gastrointestinal Neoplasms
Esophagogastric Junction

Interventions

DRUG

No Results Yet

NCT04588883 | COMPLETED | NA

843 participants

Strengthening Families Living With HIV in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-09-28
Completion:: 2025-07-15

Conditions

ART
Hiv
Trust
Depression, Anxiety
PTSD
Adherence, Medication

Interventions

BEHAVIORAL

No Results Yet

NCT04580420 | RECRUITING | PHASE2

28 participants

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-04-15
Completion:: 2031-12-30

Conditions

Primary Hyperoxaluria Type 1
End Stage Renal Disease

Interventions

DRUG

No Results Yet

NCT04575688 | ENROLLING_BY_INVITATION | PHASE4

100 participants

Periarticular Injection Versus Popliteal Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-07-13
Completion:: 2026-09-30

Conditions

Foot Surgery
Ankle Surgery

Interventions

DRUG

No Results Yet

NCT04548180 | COMPLETED

68 participants

Genome-Wide Assocation Study in Patients With Brain Injury Associated Fatigue and Altered Cognition (BIAFAC)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-06-21
Completion:: 2024-01-18

Conditions

Traumatic Brain Injury

No Results Yet

NCT04544267 | TERMINATED | PHASE3

100 participants

Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-09-15
Completion:: 2021-06-02

Conditions

Influenza

Interventions

BIOLOGICAL

Results Available

NCT04539041 | COMPLETED | PHASE1

59 participants

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-02-16
Completion:: 2024-10-17

Conditions

Progressive Supranuclear Palsy (PSP)

Interventions

DRUG

No Results Yet

NCT04536038 | COMPLETED | NA

5176 participants

Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-10-05
Completion:: 2023-05-31

Conditions

Peripheral Artery Disease

Interventions

BEHAVIORAL

Results Available

NCT04530890 | RECRUITING | NA

1000 participants

Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-03-08
Completion:: 2032-03-31

Conditions

Breast Cancer
Digestive Cancer
Gynecologic Cancer
Circulating Tumor DNA
Exosomes

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04530526 | COMPLETED | NA

26 participants

Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-07-12
Completion:: 2023-06-30

Conditions

Post-Mastectomy Chronic Pain Syndrome

Interventions

PROCEDURE

Results Available

NCT04511078 | RECRUITING | PHASE2

25 participants

Phase II Panitumumab-IRDye800 in Head & Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-04-02
Completion:: 2030-12-31

Conditions

Head and Neck Cancer

Interventions

DRUG

No Results Yet

NCT04503122 | COMPLETED

116 participants

Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-06-22
Completion:: 2025-11-13

Conditions

Paroxysmal Atrial Fibrillation

Interventions

PROCEDURE

No Results Yet

NCT04497857 | COMPLETED | NA

74 participants

Academic-Community EPINET (AC-EPINET)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2022-03-16
Completion:: 2025-07-29

Conditions

Schizophrenia
Schizoaffective Disorder
Schizophreniform Disorders
Major Depression With Psychotic Features
Bipolar Disorder With Psychotic Features

Interventions

OTHER

No Results Yet

NCT04294160 | TERMINATED | PHASE1

122 participants

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-07-22
Completion:: 2024-09-25

Conditions

BRAF V600 Colorectal Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04255615 | RECRUITING | NA

4000 participants

Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-02-12
Completion:: 2029-01-31

Conditions

Infertility
in Vitro Fertilization (IVF)
ART

Interventions

OTHER

No Results Yet

NCT04244877 | WITHDRAWN | PHASE3

0 participants

Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-09-15
Completion:: 2023-05-01

Conditions

Cirrhosis, Liver
Minimal Hepatic Encephalopathy
Small Intestinal Bacterial Overgrowth
Gastrointestinal Motility Disorder

Interventions

DRUG

No Results Yet

NCT04155710 | COMPLETED | PHASE1

7 participants

Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2020-02-19
Completion:: 2024-11-11

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04146298 | RECRUITING | PHASE1/PHASE2

30 participants

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-10-21
Completion:: 2027-06-30

Conditions

Pancreatic Cancer
Pancreatic Neoplasms
Pancreatic Ductal Adenocarcinoma
Advanced Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04123418 | TERMINATED | PHASE1

56 participants

A Study of WVT078 in Patients With Multiple Myeloma (MM)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-12-05
Completion:: 2024-12-02

Conditions

Multiple Myeloma (MM)

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04081714 | TEMPORARILY_NOT_AVAILABLE

Intermediate Expanded Access Protocol CNMAu8.EAP03

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-12-24

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT04069754 | TERMINATED | NA

10 participants

Passport to Freedom (P2F): Adaptation and Implementation of a Wellness Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-10-28
Completion:: 2021-10-23

Conditions

Trauma

Interventions

BEHAVIORAL

No Results Yet

NCT03991962 | ACTIVE_NOT_RECRUITING | PHASE2

28 participants

Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2019-09-24
Completion:: 2026-08-31

Conditions

Pancreatic Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT03976674 | COMPLETED | NA

94 participants

A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2018-02-05
Completion:: 2020-09-05

Conditions

Bariatric Surgery Candidate
Obesity

Interventions

BEHAVIORAL

No Results Yet