Clinical Trials Updated in 2025

NCT06027242 | RECRUITING | NA

120 participants

Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-02-21
Completion:: 2026-08-30

Conditions

Gastric Cancer
Immunonutrition
Gastrostomy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05981547 | ACTIVE_NOT_RECRUITING

400 participants

Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-22
Completion:: 2026-06-21

Conditions

Gestational Diabetes

Interventions

DEVICE

No Results Yet

NCT05941286 | COMPLETED | NA

533 participants

Effect of Continuous Glucose Monitoring System Alerts on Diabetes Management in the Hospital

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-18
Completion:: 2024-12-16

Conditions

Diabetes Mellitus

Interventions

DEVICE

No Results Yet

NCT05916274 | COMPLETED | NA

40 participants

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-05-31
Completion:: 2024-02-29

Conditions

Inflammatory Bowel Diseases
Crohn Disease
Ulcerative Colitis

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT05915468 | COMPLETED

306 participants

Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-07-12
Completion:: 2025-12-11

Conditions

Coronary Artery Disease

No Results Yet

NCT05913882 | RECRUITING | NA

34 participants

Combined Respiratory Training in Persons With ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-08-22
Completion:: 2026-09-30

Conditions

ALS
Respiratory Insufficiency
Dysphagia

Interventions

DEVICE

No Results Yet

NCT05910606 | ACTIVE_NOT_RECRUITING | NA

92 participants

Strong Foundations 2.0: A Digitally Delivered Fall Prevention Program.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-01
Completion:: 2026-07-16

Conditions

Fall Prevention
Bone Health
Balance

Interventions

BEHAVIORAL

No Results Yet

NCT05905302 | COMPLETED | NA

15 participants

The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-08-15
Completion:: 2024-09-20

Conditions

Parkinson Disease
Deep Brain Stimulation

Interventions

OTHER

Results Available

NCT05891119 | COMPLETED | EARLY_PHASE1

21 participants

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-06-03
Completion:: 2024-08-28

Conditions

Atopic Dermatitis

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT05854485 | COMPLETED | NA

24 participants

Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-06
Completion:: 2025-05-30

Conditions

Stroke

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05830760 | WITHDRAWN | NA

0 participants

Expression of Sodium-glucose Co-transporter 2 in Human Heart

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-06-30
Completion:: 2025-10-31

Conditions

Aortic Valve Stenosis

Interventions

BIOLOGICAL

No Results Yet

NCT05827926 | COMPLETED | PHASE1/PHASE2

1758 participants

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-14
Completion:: 2024-12-03

Conditions

SARS-CoV-2
Influenza

Interventions

BIOLOGICAL

Results Available

NCT05803720 | COMPLETED | NA

59 participants

HIV Provider Intervention to Address Intersectional Stigma and Medical Mistrust

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-01
Completion:: 2024-03-31

Conditions

Stigma, Social

Interventions

BEHAVIORAL

Results Available

NCT05763901 | COMPLETED | NA

151 participants

IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2021-04-01
Completion:: 2024-05-16

Conditions

Genu Varum
Genu Valgus
Flat Feet
Cavus Foot
Scoliosis Idiopathic
Varus; Talipes
Valgus, Talipes
Laxity of Ligament
Hyperlordosis
Hyperkyphosis
Angular Limb Deformity

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05746845 | COMPLETED

100 participants

Implication of 5-HT7 Receptor in Inflammatory Mechanisms in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-06
Completion:: 2024-07-01

Conditions

Healthy
Multiple Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT05696132 | TERMINATED | PHASE2

1 participants

Evaluation of the Decolonization Rate and Acceptance of a Complete Nasal Decolonization Kit With Povidone Iodine for MRSA Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-11-21
Completion:: 2025-12-04

Conditions

MRSA

Interventions

DRUG

No Results Yet

NCT05692518 | COMPLETED | NA

15 participants

MagDI Diversion Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-12-19
Completion:: 2024-08-23

Conditions

Type 2 Diabetes
Obesity

Interventions

DEVICE

No Results Yet

NCT05690438 | COMPLETED

773 participants

Prediction of the Post-intensive Care Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-01-09
Completion:: 2025-04-30

Conditions

Critical Care

No Results Yet

NCT05669716 | TERMINATED

726 participants

Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-09
Completion:: 2025-09-25

Conditions

Healthy Volunteers
Vaping Teens

No Results Yet

NCT05656430 | COMPLETED | NA

24 participants

ICBT for Psychological Symptoms Related to the COVID-19 Pandemic Remaining After Societal Opening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-02-01
Completion:: 2023-09-30

Conditions

Depression Symptoms
Anxiety Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT05637346 | COMPLETED | NA

50 participants

Vessel- and Bone-based Ultrasound Registration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2021-12-05
Completion:: 2025-12-11

Conditions

Abdominal Cancer

Interventions

PROCEDURE

No Results Yet

NCT05635799 | COMPLETED | NA

70 participants

Virtual Reality Applied to the Evaluation and Rehabilitation of Locomotion - Study of Tolerance in the Lower Limb Amputee

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-06
Completion:: 2025-11-26

Conditions

Unilateral Amputation of the Lower Limb

Interventions

OTHER

No Results Yet

NCT05619367 | AVAILABLE

A Compassionate Use (CU) Program of Odronextamab

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-12-23

Conditions

Relapsed or Refractory (R/R) Follicular Lymphoma (FL)
Diffuse Large B-Cell Lymphoma (DLBCL)
B-Cell Non-Hodgkin Lymphoma (NHL)
High-Grade B-Cell Lymphoma (HGBCL)

Interventions

DRUG

No Results Yet

NCT05598970 | COMPLETED | NA

3585 participants

Family and Childhood Development: The Next Generation ('Kizazi Kijacho')

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-09-26
Completion:: 2024-06-05

Conditions

Parenting
Early Child Development

Interventions

OTHER

No Results Yet

NCT05598008 | COMPLETED

85 participants

Effects of Glucagon-like-Peptide-1 Analogues on Sexuality

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-11-25
Completion:: 2025-10-24

Conditions

Sexual Desire

No Results Yet

NCT05595681 | TERMINATED | PHASE1

21 participants

Effect of Mesenchymal Stem Cells on Healing of Foot Ulcers in Diabetes Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-12-15
Completion:: 2025-11-28

Conditions

Diabetic Foot Ulcer
Mesenchymal Stromal Cells

Interventions

DRUG

No Results Yet

NCT05576051 | COMPLETED

9159 participants

To Estimate the Efficacy of Treatment With TNFi as Monotherapy or Combination Therapy With MTX and Compare and Contrast Efficacy With Tofacitinib as Monotherapy and Combination Therapy in a Real World Setting.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2015-06-04
Completion:: 2015-10-07

Conditions

Rheumatoid Arthritis

Interventions

OTHER

Results Available

NCT05570006 | COMPLETED | PHASE2

30 participants

Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-16
Completion:: 2024-12-23

Conditions

Ulcerative Colitis

Interventions

DRUG

Results Available

NCT05555589 | RECRUITING | PHASE3

70 participants

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-11
Completion:: 2026-04-30

Conditions

Neurotrophic Keratopathy

Interventions

DRUG

No Results Yet

NCT05546515 | COMPLETED | PHASE2

20 participants

Suvorexant for Opioid/Stimulant Co-use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-12-01
Completion:: 2024-11-30

Conditions

Opioid Use Disorder
Stimulant Use Disorder

Interventions

DRUG

Results Available

NCT05494723 | NOT_YET_RECRUITING | PHASE1

6 participants

Safety and Efficacy of YB-1113 in Treatment of POI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2026-12-09
Completion:: 2028-01-09

Conditions

POI

Interventions

DRUG

No Results Yet

NCT05483933 | COMPLETED | PHASE1

86 participants

Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-08-18
Completion:: 2025-02-07

Conditions

Platinum-resistant Ovarian Cancer
Fallopian Tube Cancer
Epithelial Ovarian Cancer
Ovarian Cancer
Platinum-Resistant Fallopian Tube Carcinoma
Platinum-Resistant Primary Peritoneal Carcinoma
Primary Peritoneal Carcinoma

Interventions

DRUG

Results Available

NCT05470023 | RECRUITING | NA

275 participants

Imaging-based Assessment of Oral Biofilm and Gingival Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-09-01
Completion:: 2028-12-31

Conditions

Plaque, Dental
Gingivitis

Interventions

OTHER

No Results Yet

NCT05469373 | RECRUITING

86 participants

ESIS in Pediatric DRE

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-02-17
Completion:: 2026-06-30

Conditions

Epilepsy

No Results Yet

NCT05445323 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

8 participants

Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-08-24
Completion:: 2029-09-30

Conditions

Friedreich Ataxia
Cardiomyopathy, Secondary

Interventions

GENETIC

No Results Yet

NCT05418049 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-09-08
Completion:: 2025-10-28

Conditions

Fragile X Syndrome

Interventions

DRUG

No Results Yet

NCT05414903 | RECRUITING | NA

90 participants

Reading Outcomes in Children With Vestibular Loss

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-06-06
Completion:: 2026-06-30

Conditions

Vestibular Disorder
Hearing Loss, Sensorineural

Interventions

BEHAVIORAL

No Results Yet

NCT05399498 | COMPLETED | PHASE2

9 participants

Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-01
Completion:: 2025-12-01

Conditions

Borderline Personality Disorder
Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05371210 | COMPLETED | NA

105 participants

An End-to-end System for Assessment and Intervention of Frailty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2021-03-15
Completion:: 2022-06-16

Conditions

Frailty

Interventions

OTHER

No Results Yet

NCT05337982 | RECRUITING | NA

49 participants

Eccentric Muscle Training, Stimulation, and Biomarkers in SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2022-05-17
Completion:: 2026-12-31

Conditions

Spinal Cord Injuries
Healthy

Interventions

OTHER

No Results Yet