Clinical Trials Updated in 2025

NCT06239116 | RECRUITING | PHASE1/PHASE2

150 participants

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-03-05
Completion:: 2027-11-01

Conditions

Hypothalamic Obesity
Prader-Willi Syndrome
PWS

Interventions

DRUG

No Results Yet

NCT06229366 | ACTIVE_NOT_RECRUITING | PHASE1

142 participants

[Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-04-03
Completion:: 2027-09-30

Conditions

Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Oligometastatic Prostate Carcinoma
Hormone Sensitive Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06218511 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-11-22
Completion:: 2025-08-28

Conditions

Hepatocellular Carcinoma

Interventions

BIOLOGICAL
COMBINATION_PRODUCT
OTHER

No Results Yet

NCT06210061 | COMPLETED | NA

78 participants

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-01-20
Completion:: 2025-03-01

Conditions

Propofol
Fentanyl
Dexmedetomidine
Sevoflurane
Spine Surgery
Somatosensory Evoked Potential
Motor Evoked Potential

Interventions

DRUG

No Results Yet

NCT06179784 | COMPLETED | NA

12 participants

Personalising Psychotherapy for Chronic Primary Pain Using Network Analysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-11-17
Completion:: 2025-08-08

Conditions

Chronic Primary Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06173154 | COMPLETED | NA

85 participants

Feasibility Assessment of Implementing a Care System to PREVENT Iatrogenic Dependency (ID)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-06-12
Completion:: 2025-05-20

Conditions

Aged

Interventions

OTHER

No Results Yet

NCT06167213 | NOT_YET_RECRUITING | NA

125 participants

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2027-01-31
Completion:: 2029-03-31

Conditions

Mitral Regurgitation
Mitral Valve Disease
Mitral Stenosis

Interventions

DEVICE

No Results Yet

NCT06161818 | RECRUITING | PHASE2

216 participants

Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric Junction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-09-12
Completion:: 2029-09-01

Conditions

Esophageal Cancer
Adenocarcinoma of the Esophagus

Interventions

DRUG

No Results Yet

NCT06157411 | COMPLETED | NA

56 participants

Adapting Mindful Eating Program for French Overweight/Obese Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-02-16
Completion:: 2025-01-10

Conditions

Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06155084 | RECRUITING | PHASE1/PHASE2

84 participants

A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-12-26
Completion:: 2026-03-31

Conditions

Metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06149403 | ACTIVE_NOT_RECRUITING | PHASE3

41 participants

A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-12-11
Completion:: 2028-03-31

Conditions

MPS-IH (Hurler Syndrome)

Interventions

GENETIC

No Results Yet

NCT06129188 | COMPLETED | PHASE1

105 participants

Comparison of Procedural Sedation in TEE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-02-25
Completion:: 2025-11-26

Conditions

Anesthesia

Interventions

DRUG

No Results Yet

NCT06099379 | RECRUITING | PHASE1/PHASE2

100 participants

Modulation of THC Effects by CBD: a Dose-ranging Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-06-27
Completion:: 2026-07-31

Conditions

Cannabis
THC

Interventions

DRUG

No Results Yet

NCT06094582 | COMPLETED

47 participants

Knowledges and Use of Cannabidiol in Older Adults

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-10-26
Completion:: 2023-12-26

Conditions

Aging
Frailty

Interventions

OTHER

No Results Yet

NCT06091631 | COMPLETED | NA

100 participants

Magnesium Sulfate in Surgical Stress Attenuation Postoperative Sore Throat and Stress Response Induced Tracheal Intubation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-11-15
Completion:: 2025-02-03

Conditions

Anesthesia Complication
Anesthesia Intubation Complication

Interventions

PROCEDURE

No Results Yet

NCT06055946 | COMPLETED

70 participants

Symmcora® Long-term Bidirectional Barbed Suture for Anastomosis in Patients Undergoing Robot Assisted Radical Prostatectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-11-07
Completion:: 2024-12-19

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT06041334 | RECRUITING | NA

50 participants

Evaluation of muLtimodal and Non-invasive SPINa Bifida Neurovessels During Prospective Follow-up

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-01-18
Completion:: 2027-07-18

Conditions

Spina Bifida

Interventions

BIOLOGICAL
DIAGNOSTIC_TEST

No Results Yet

NCT06036823 | COMPLETED | PHASE4

384 participants

5 Versus 10 Units of Insulin in Hyperkalemia Management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-10-01
Completion:: 2025-09-30

Conditions

Hyperkalemia
Potassium Imbalance
Electrolyte Imbalance
Electrolyte Disturbance

Interventions

DRUG

No Results Yet

NCT06035393 | TERMINATED | PHASE2

82 participants

A Study to Assess the Efficacy and Safety of HRG2005 Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-01-15
Completion:: 2025-02-17

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DRUG

No Results Yet

NCT06018415 | COMPLETED | NA

103 participants

Effects of Early and Late Time-restricted Eating on Overweight Adults With Metabolic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-05-07
Completion:: 2024-10-16

Conditions

Metabolic Syndrome
Overweight and Obesity
Time Restricted Eating

Interventions

BEHAVIORAL

No Results Yet

NCT05997693 | RECRUITING | PHASE3

700 participants

One-Month DAPT in CABG Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-08-15
Completion:: 2027-01-31

Conditions

Chronic Coronary Disease

Interventions

DRUG

No Results Yet

NCT05992688 | RECRUITING | NA

150 participants

The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-09-19
Completion:: 2026-05-31

Conditions

Adiposity
Insulin Sensitivity
Weight Gain
Blood Pressure
Lipoproteins

Interventions

OTHER

No Results Yet

NCT05978180 | COMPLETED | NA

252 participants

Safety of Use and Efficacy of Pandora for Patients Suffering From Gonarthrosis (PANDORA2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-10-18
Completion:: 2025-11-13

Conditions

Knee Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT05948592 | COMPLETED | PHASE2

76 participants

Bacteriophage Therapy TP-102 in Patients With Diabetic Foot Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-11-08
Completion:: 2025-10-30

Conditions

Diabetic Foot Infection

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05932485 | COMPLETED | NA

108 participants

Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-06-01
Completion:: 2024-06-01

Conditions

Stellate Ganglion Block

Interventions

PROCEDURE

No Results Yet

NCT05914805 | COMPLETED | PHASE3

762 participants

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-08-17
Completion:: 2025-07-16

Conditions

Alopecia, Androgenetic

Interventions

DRUG

No Results Yet

NCT05898139 | COMPLETED

22 participants

Describe to Better Understand, the Mealtime of People With Parkinson's Disease Dependent on Food Intake

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-02-01
Completion:: 2025-10-13

Conditions

Parkinson Disease
Deglutition Disorders

No Results Yet

NCT05886270 | COMPLETED | NA

300 participants

Implementation of the Child Housing Assessment for a Safe Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-06-24
Completion:: 2025-12-05

Conditions

Accident Injury
Home Injury

Interventions

OTHER

No Results Yet

NCT05876091 | TERMINATED | NA

21 participants

Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-08-30
Completion:: 2024-10-08

Conditions

Tobacco-Related Carcinoma

Interventions

OTHER
PROCEDURE

Results Available

NCT05874804 | COMPLETED | NA

28 participants

Carry Life@ UF System Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-09-19
Completion:: 2025-10-24

Conditions

End Stage Renal Disease

Interventions

DEVICE
DRUG

No Results Yet

NCT05845645 | COMPLETED | PHASE1

73 participants

A Study to Test Bioavailability of of 2 New Formulations of UCB0599 in Healthy Participants in Part A and to Test Safety, Tolerability, and Pharmacokinetic (PK) of UCB0599 in Healthy Japanese and Chinese Participants in Part B

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-05-31
Completion:: 2024-04-13

Conditions

Healthy Study Participants

Interventions

DRUG
OTHER

Results Available

NCT05844332 | COMPLETED

347 participants

LUTATHERA Injection General Use Result Survey

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-12-17
Completion:: 2024-06-27

Conditions

Somatostatin Receptor-positive Neuroendocrine Tumor

Interventions

OTHER

No Results Yet

NCT05834868 | COMPLETED | PHASE3

1040 participants

Efficacy and Safety of THDB0206 Compared to Insulin Lispro Injection in Participants With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-05-06
Completion:: 2024-12-10

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT05826912 | ENROLLING_BY_INVITATION | PHASE2

672 participants

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2024-08-01
Completion:: 2028-08-31

Conditions

Traumatic Brain Injury

Interventions

DRUG

No Results Yet

NCT05818085 | COMPLETED | PHASE2/PHASE3

300 participants

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-08-11
Completion:: 2025-01-30

Conditions

Gout

Interventions

DRUG
OTHER

No Results Yet

NCT05817227 | RECRUITING

300 participants

Selenoproteins as Prognostic Markers and Therapeutic Targets in Breast Cancer.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-05-19
Completion:: 2027-11-19

Conditions

Breast Cancer

No Results Yet

NCT05789303 | RECRUITING | PHASE2

83 participants

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-05-30
Completion:: 2028-07-01

Conditions

Multiple Myeloma
Relapse Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05770518 | COMPLETED | NA

51 participants

Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-03-07
Completion:: 2024-06-30

Conditions

Paradoxical Vocal Fold Motion
Vocal Cord Dysfunction

Interventions

BEHAVIORAL

No Results Yet

NCT05768165 | ACTIVE_NOT_RECRUITING | NA

87 participants

High-intensity Interval Exercise in Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-08-16
Completion:: 2023-06-30

Conditions

Rheumatoid Arthritis

Interventions

BEHAVIORAL

No Results Yet

NCT05757401 | COMPLETED

286 participants

Sleep Quality After Cesarean Delivery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-03-14
Completion:: 2024-05-15

Conditions

Cesarean Section Complications
Sleep Disturbance
Perioperative Complication

No Results Yet