Clinical Trials Updated in 2025

NCT07290608 | COMPLETED | NA

59 participants

DOACT Algorithm Versus AI-Based Decision Models in Oral Anticoagulant Therapy for Vascular Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-01-20
Completion:: 2025-10-10

Conditions

Deep Vein Thrombosis
Superficial Thrombophlebitis
Pulmonary Thromboembolisms
Clinical Decision Support Systems
Artificial Intelligence

Interventions

OTHER

No Results Yet

NCT07290543 | RECRUITING | NA

578 participants

Web-Based Toolkit to Improve Cancer-Related Emotional Distress and Anxiety in Rural Older Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-08-26
Completion:: 2031-08-26

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07290491 | RECRUITING | PHASE3

854 participants

Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-06-19
Completion:: 2029-05-10

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07290465 | NOT_YET_RECRUITING | NA

56 participants

Pain Perception and Exercise-Induced Hypoalgesia Across Circadian Rhythms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-31
Completion:: 2026-03-31

Conditions

Exercise Induced Hypoalgesia
Circadian Rhythm
Pain Perception
Healthy Participants
Chronotype
Physical Therapy

Interventions

BEHAVIORAL

No Results Yet

NCT07290426 | NOT_YET_RECRUITING | NA

40 participants

Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-03-31
Completion:: 2028-12-31

Conditions

Rosacea
Vascular Diseases
Port-Wine Stain

Interventions

DEVICE

No Results Yet

NCT07290413 | ACTIVE_NOT_RECRUITING | PHASE2

78 participants

Photobiomodulation for the Prevention of Oral Mucositis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-01
Completion:: 2026-12-31

Conditions

Oral Mucositis

Interventions

DEVICE

No Results Yet

NCT07290400 | NOT_YET_RECRUITING | PHASE2

36 participants

Effect of Moderate Alcohol on Absorption and Onset of Hezkue Sildenafil Suspension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-04-15
Completion:: 2026-06-15

Conditions

Erectile Dysfunction

Interventions

DRUG
OTHER

No Results Yet

NCT07290374 | NOT_YET_RECRUITING | NA

45 participants

Mckenzie Versus Maitland Cervical Mobilization Technique in Management of Non-specific Neck Pain.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-12
Completion:: 2026-04-15

Conditions

Chronic Non-specific Neck Pain

Interventions

OTHER

No Results Yet

NCT07290348 | COMPLETED | NA

40 participants

Effect of Dynamic Hand Splint on Hand ROM Post Extensor Tendon Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-01
Completion:: 2024-12-01

Conditions

Splints
Range of Motion
Extensor Tendons of Finger Anomalies

Interventions

OTHER

No Results Yet

NCT07290322 | ACTIVE_NOT_RECRUITING | NA

8 participants

Denture Retention of Intra-orally Scanned Versus Extra-orally Scanned Digitally Printed Maxillary Denture in Completely Edentulous Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-12-03
Completion:: 2026-09-01

Conditions

Complete Edentulism

Interventions

DEVICE

No Results Yet

NCT07290231 | RECRUITING | NA

56 participants

Effects of Core Strengthening Exercises With Diapgragmatic Breathing Versus Core Strengthening Exercises With Pilate Breathing in Diabetes Type II Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-08-06
Completion:: 2026-01-03

Conditions

Diabetes Type II

Interventions

OTHER

No Results Yet

NCT07290218 | NOT_YET_RECRUITING

15 participants

Tridimensional Robotic Assessment of Neglect in Brain Injured Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-01
Completion:: 2026-10-31

Conditions

Neglect
Brain Injured Patients
Stroke
Unilateral Spatial Neglect (USN)
Post-stroke Cognitive Impairment

Interventions

DEVICE

No Results Yet

NCT07290192 | NOT_YET_RECRUITING | NA

110 participants

This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-02-01
Completion:: 2026-08-01

Conditions

Pulp Necrosis

Interventions

PROCEDURE

No Results Yet

NCT07290166 | NOT_YET_RECRUITING | PHASE2

42 participants

A Phase II Study to Evaluate the Efficacy and Safety of Anti-HER2 Triple-targeted Drugs Combined With CDK4/6 Inhibitors in Neoadjuvant Therapy for ER-positive HER2-positive Breast Cancer Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-31
Completion:: 2027-10-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT07290153 | RECRUITING

120 participants

Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-01
Completion:: 2027-06-30

Conditions

Breast Cancer Female NOS
General Anxiety Disorder
Depressive Disorder

No Results Yet

NCT07290127 | ENROLLING_BY_INVITATION | NA

120 participants

A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-13
Completion:: 2026-05-31

Conditions

Post-traumatic Stress Disorder (PTSD)
Postpartum Mental Health

Interventions

BEHAVIORAL

No Results Yet

NCT07290114 | RECRUITING | NA

147 participants

Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-01-13
Completion:: 2026-06-30

Conditions

Stress Urinary Incontinence (SUI)

Interventions

PROCEDURE

No Results Yet

NCT07290101 | NOT_YET_RECRUITING | NA

15 participants

A First-in-Man Clinical Trial to Evaluate the Safety and Feasibility of ICS-Elpis in Patients With Iliac Artery Stenosis or Occlusion Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-08
Completion:: 2027-12-01

Conditions

Iliac Artery Stenosis
Iliac Artery Occlusion

Interventions

DEVICE

No Results Yet

NCT07289607 | NOT_YET_RECRUITING | NA

80 participants

Effect of TECAR on Cervical Radiculopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-01
Completion:: 2026-03-05

Conditions

Cervical Radiculopathy

Interventions

DEVICE

No Results Yet

NCT07288450 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

Terazosin And Metabolic Engagement in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-09-01
Completion:: 2030-09-01

Conditions

Parkinson's Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07288242 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-12-18

No Results Yet

NCT07288060 | ENROLLING_BY_INVITATION | NA

33 participants

The Effect of Mulligan and GMI on Distal Radius Proprioception

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-01
Completion:: 2026-08-15

Conditions

Distal Radial Fracture
Rehabilitation
Mulligan Mobilization
Motor Imagery Training
Physical Therapy

Interventions

OTHER

No Results Yet

NCT07287839 | NOT_YET_RECRUITING | PHASE2

60 participants

Parcel-guided rTMS for Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-15
Completion:: 2028-06-01

Conditions

Treatment Resistant Depression (TRD)

Interventions

DEVICE

No Results Yet

NCT07284823 | RECRUITING | NA

10 participants

Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Parkinson Disease (PD)

Interventions

DEVICE

No Results Yet

NCT07282184 | RECRUITING | PHASE1/PHASE2

144 participants

Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-26
Completion:: 2027-06-30

Conditions

Hepotacellular Carcinoma

Interventions

COMBINATION_PRODUCT
PROCEDURE
OTHER

No Results Yet

NCT07280767 | COMPLETED

213 participants

Does Implementation of Feedback Informed Therapy (FIT) Improve Access to Psychotherapy in Psychiatry?

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-09-01
Completion:: 2025-11-30

Conditions

Psychiatric Diagnosis

Interventions

BEHAVIORAL

No Results Yet

NCT07278180 | COMPLETED

40 participants

Effects of Platelet and Leukocyte-rich Fibrin on Alveolar Ridge Maintenance Through Three-dimensional Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2016-01-20
Completion:: 2018-02-20

Conditions

Caries Active
Tooth Decay
Tooth Loss / Rehabilitation

Interventions

PROCEDURE

No Results Yet

NCT07277465 | COMPLETED | NA

60 participants

Role of the Microbiota in Obesity: Effect After Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2021-03-03
Completion:: 2025-01-31

Conditions

Obese Patients With Bariatric Surgery

Interventions

PROCEDURE

No Results Yet

NCT07276425 | RECRUITING

40 participants

Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-01
Completion:: 2028-06-01

Conditions

Prurigo Nodularis (PN)

Interventions

DRUG

No Results Yet

NCT07275866 | RECRUITING | NA

20 participants

Multi-strain Probiotic Effects on Self-Reported Constipation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-03
Completion:: 2026-04-30

Conditions

Constipation
Probiotic
Probiotic Intervention

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07275437 | NOT_YET_RECRUITING | NA

344 participants

Effectiveness and Safety of Uptitration of Guideline Directed MEdical Therapy in Heart Failure With Reduced Ejection Fraction With Limited Kidney Function Assessments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-04-01
Completion:: 2030-01-01

Conditions

Heart Failure
Heart Failure and Reduced Ejection Fraction
Heart Failure and Mildly Reduced Ejection Fraction

Interventions

OTHER

No Results Yet

NCT07275333 | RECRUITING | NA

1000 participants

Human Papillomavirus Self-sampling for Enhancing Cervical Screening During the War in Ukraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-04-01
Completion:: 2026-08-31

Conditions

Cervical Cancer
Cervical Cancer Screening
Human Papillomavirus (HPV) Infection
Cervical Intraepithelial Neoplasia

Interventions

DEVICE

No Results Yet

NCT07275073 | RECRUITING | PHASE1

200 participants

JMT106 Injection in the Treatment of Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-09-25
Completion:: 2026-11-05

Conditions

Advanced Solid Tumor
Lung Squamous Cell Carcinoma
Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT07274553 | ACTIVE_NOT_RECRUITING | NA

80 participants

Mindfulness-Based Stress Reduction for Adolescents: Effects on Game Addiction, Stress, and Sleep

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-03
Completion:: 2025-11-10

Conditions

Adolescent Behaviour Disorder
Stress Reduction
Sleep Quality
Digital Addiction

Interventions

BEHAVIORAL

No Results Yet

NCT07274540 | COMPLETED | NA

30 participants

Use Of Orthotics To Reduce Pain In Musicians

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2020-01-16
Completion:: 2020-02-28

Conditions

Musculoskeletal Pain
Overuse Syndrome
Tendinopathy, Elbow
Musculoskeletal Pain and Functional Impairment in Musicians

Interventions

DEVICE

No Results Yet

NCT07274371 | ACTIVE_NOT_RECRUITING | NA

30 participants

A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-06
Completion:: 2026-03-30

Conditions

Sleep Disturbances in Perimenopause

Interventions

BEHAVIORAL

No Results Yet

NCT07274215 | RECRUITING | NA

200 participants

Paragastric Block for Pain and PONV in Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-01
Completion:: 2025-12-30

Conditions

Postoperative Nausea and Vomiting
Postoperative Pain After Laparoscopic Sleeve Gastrectomy

Interventions

DRUG

No Results Yet

NCT07273513 | NOT_YET_RECRUITING | NA

951 participants

"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-01-15
Completion:: 2026-12-31

Conditions

Hypertension
Diabete Mellitus
Hyperlipidemia
Post PCI
Post CABG

Interventions

BEHAVIORAL

No Results Yet

NCT07273318 | COMPLETED | NA

60 participants

Osmonar® Nasal Gel Versus Saline Solution in Patients With Dry Nose

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2021-09-09
Completion:: 2021-10-20

Conditions

Dry Nose

Interventions

DEVICE
OTHER

No Results Yet

NCT07272538 | COMPLETED

84 participants

Predicting Chemotherapy Toxicity Using FRAIL and FIND in Older Adults With Gastrointestinal Cancers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-12-20
Completion:: 2024-12-20

Conditions

Gastrointestinal Cancers
Frailty at Older Adults
Chemotherapy

Interventions

OTHER

No Results Yet