Clinical Trials Updated in 2025

NCT06154512 | COMPLETED

724 participants

A Real-world, Multi-center, Prospective, Observational Study for PNH in China

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-11-10
Completion:: 2025-12-03

Conditions

Paroxysmal Nocturnal Hemoglobinuria

No Results Yet

NCT06119113 | COMPLETED | NA

300 participants

Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-02-22
Completion:: 2023-07-22

Conditions

Cesarean Section; Infection
Scar

Interventions

OTHER

Results Available

NCT06110403 | RECRUITING | PHASE1/PHASE2

35 participants

Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-09-29
Completion:: 2026-09-30

Conditions

Copd

Interventions

DRUG

No Results Yet

NCT06097130 | COMPLETED

40 participants

Batch Fermentation and Microbiome Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2020-08-18
Completion:: 2020-08-25

Conditions

Healthy

No Results Yet

NCT06086301 | COMPLETED | NA

42 participants

Pilot Testing PICTURE-THIS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-09
Completion:: 2025-10-16

Conditions

Post-intensive Care Syndrome
Transitional Care
Critical Care
Health Services

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06083597 | ENROLLING_BY_INVITATION

55 participants

Development of a Patient-reported Outcome Measure for Women With Chronic Pelvic Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-07-01
Completion:: 2026-12-31

Conditions

Chronic Pelvic Pain Syndrome
Pelvic Congestive Syndrome

Interventions

OTHER

No Results Yet

NCT06082973 | COMPLETED | NA

15 participants

Dual-hormone Artificial Pancreas Versus Single-hormone Under Exercise and a Meal Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-05-15
Completion:: 2025-05-30

Conditions

Type 1 Diabetes

Interventions

DEVICE

No Results Yet

NCT06079606 | ACTIVE_NOT_RECRUITING

200 participants

The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2022-09-10
Completion:: 2025-02-28

Conditions

Immune Responses
Antibiotic Treatment

Interventions

OTHER

No Results Yet

NCT06070116 | ACTIVE_NOT_RECRUITING | PHASE2

300 participants

Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-04-05
Completion:: 2026-09-01

Conditions

Onchocercal Subcutaneous Nodule
Onchocerciasis
Onchocerciasis, Ocular
Onchocerca Infection
Tropical Disease

Interventions

DRUG

No Results Yet

NCT06068530 | RECRUITING | PHASE4

10000 participants

Mass Vaccine and Drug Administration, Bangladesh

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-02-15
Completion:: 2028-02-01

Conditions

Plasmodium Falciparum Malaria

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06053450 | COMPLETED | NA

20 participants

The Effect of Essential Oil Inhalation Patches on Perceived Burn-out & Stress on an Inpatient Medical-surgery Unit.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-06-30
Completion:: 2025-11-20

Conditions

Nursing Personnel

Interventions

OTHER

No Results Yet

NCT06049225 | COMPLETED | NA

90 participants

Medical Nutrition Therapy and Diabetes Self-Management Education for People With Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-06-01
Completion:: 2025-07-31

Conditions

Type 2 Diabetes
Physical Disability

Interventions

BEHAVIORAL

No Results Yet

NCT06033391 | COMPLETED | NA

94 participants

Mobile App for Obsessive-compulsive Disorder in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-04-09
Completion:: 2024-05-24

Conditions

Obsessive-Compulsive Disorder in Adolescence

Interventions

DEVICE

No Results Yet

NCT06029595 | TERMINATED | PHASE2

517 participants

Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-11-26
Completion:: 2025-12-09

Conditions

Uncontrolled Asthma

Interventions

DRUG

No Results Yet

NCT06015750 | WITHDRAWN | PHASE4

0 participants

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2026-07-29
Completion:: 2030-03-13

Conditions

Hypophosphatasia

Interventions

DRUG

No Results Yet

NCT06005220 | COMPLETED | NA

143 participants

SBD121, a Synbiotic Medical Food for RA Management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-09-30
Completion:: 2025-10-06

Conditions

Rheumatoid Arthritis

Interventions

OTHER

No Results Yet

NCT06001177 | COMPLETED | PHASE2

55 participants

A Study of Efficacy, Safety, and Tolerability of KAN-101 in People With Celiac Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-12-13
Completion:: 2025-01-03

Conditions

Celiac Disease
Coeliac Disease

Interventions

DRUG

Results Available

NCT05998278 | RECRUITING | NA

330 participants

Personalized Optimization of Systematic Prostate Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-23
Completion:: 2025-12-30

Conditions

Prostate Adenocarcinoma

Interventions

PROCEDURE

No Results Yet

NCT05959655 | COMPLETED | NA

38 participants

Modern Urodynamics System Efficacy (MUSE) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-21
Completion:: 2024-04-18

Conditions

Urologic Diseases
Urodynamics

Interventions

DEVICE

Results Available

NCT05957978 | COMPLETED | PHASE2

52 participants

LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-03-29
Completion:: 2025-06-27

Conditions

Primary Visceral Leishmaniasis

Interventions

DRUG

No Results Yet

NCT05943444 | RECRUITING | NA

256 participants

Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-08
Completion:: 2027-08-08

Conditions

Rectal Neoplasms
Low Anterior Resection Syndrome
Anastomotic Leak
Quality of Life

Interventions

PROCEDURE

No Results Yet

NCT05940350 | RECRUITING | NA

60 participants

Telerehabilitation-Based Coaching Interventions (TeleSCoP) for Patients With Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-02-01
Completion:: 2025-12-31

Conditions

Ischemic Stroke
Coaching

Interventions

BEHAVIORAL

No Results Yet

NCT05906446 | COMPLETED | NA

50 participants

Post-acute Multicomponent Frailty Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-06-15
Completion:: 2024-10-31

Conditions

Frailty

Interventions

OTHER

No Results Yet

NCT05902533 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

33 participants

REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-14
Completion:: 2026-08-14

Conditions

Anal Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT05894005 | RECRUITING | NA

44 participants

The Use of Immersive 360-degree Video in Improving Spatial Orientation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-11-08
Completion:: 2026-07-31

Conditions

Virtual Reality

Interventions

OTHER

No Results Yet

NCT05884476 | RECRUITING | NA

180 participants

Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-01-08
Completion:: 2027-06-30

Conditions

Suicidal Ideation
Suicide, Attempted

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT05860296 | TERMINATED | PHASE1/PHASE2

36 participants

Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-05-31
Completion:: 2025-12-01

Conditions

Lung Cancer, Nonsmall Cell
Lung Cancer Stage IV
Lung Cancer Metastatic

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05850364 | COMPLETED | PHASE3

1442 participants

A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-05-22
Completion:: 2025-02-13

Conditions

Poliomyelitis
Polio

Interventions

BIOLOGICAL

No Results Yet

NCT05838677 | COMPLETED | NA

380 participants

Pain at Work Toolkit in Employees With Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-07-01
Completion:: 2025-07-22

Conditions

Chronic Pain
Pain, Chronic

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05837936 | RECRUITING

600 participants

Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-03-28
Completion:: 2028-03-31

Conditions

Extubation

Interventions

OTHER

No Results Yet

NCT05815238 | COMPLETED

60 participants

Changes in Foot Posture With Age: Functional and Balance Effects

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-03-01
Completion:: 2025-03-01

Conditions

Foot Posture Index Score

No Results Yet

NCT05810948 | COMPLETED | PHASE2

73 participants

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-02-21
Completion:: 2025-07-02

Conditions

Lupus Nephritis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05805774 | RECRUITING | NA

148 participants

pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2025-10-17
Completion:: 2030-12-10

Conditions

Distal Femur Fracture
Periprosthetic Fracture Around Prosthetic Joint Implant Knee
Knee Fracture

Interventions

PROCEDURE

No Results Yet

NCT05801939 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Cevostamab Following CAR T Cell Therapy for RRMM

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-07-11
Completion:: 2027-05-31

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05791864 | RECRUITING | PHASE1/PHASE2

16 participants

A First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Gene Therapy With TTX-381 for the Ocular Manifestations Associated With Neuronal Ceroid Lipofuscinosis Type 2 (CLN2) Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-05-17
Completion:: 2026-07-30

Conditions

Neuronal Ceroid Lipofuscinosis Type 2

Interventions

GENETIC

No Results Yet

NCT05782543 | RECRUITING | NA

240 participants

Renal Ex Vivo Warm Advanced Resuscitation Through Machine Perfusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2024-12-15
Completion:: 2027-12-01

Conditions

Kidney Transplant; Complications

Interventions

PROCEDURE

No Results Yet

NCT05770947 | COMPLETED | NA

25 participants

Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-01-24
Completion:: 2025-06-27

Conditions

Bulimia Nervosa
Overweight or Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05764161 | COMPLETED | PHASE3

190 participants

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-06-12
Completion:: 2024-12-30

Conditions

Prurigo Nodularis

Interventions

DRUG

Results Available

NCT05758415 | TERMINATED | PHASE3

60 participants

Study of Efficacy and Safety of Secukinumab in Participants With Moderate-severe Rotator Cuff Tendinopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-08-02
Completion:: 2024-10-17

Conditions

Rotator Cuff Tendinopathy

Interventions

DRUG

Results Available

NCT05742178 | RECRUITING | NA

2160 participants

NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-18
Start Date:: 2023-07-05
Completion:: 2026-10-01

Conditions

Cancer Screening

Interventions

BEHAVIORAL

No Results Yet