Clinical Trials Updated in 2025

NCT04367181 | COMPLETED | NA

100 participants

DCS Study in Extremely Premature Newborns

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-03-15
Completion:: 2023-05-31

Conditions

Premature Birth
Extremely Low Birth Weight
Infant, Small for Gestational Age
Intracerebral Hemorrhage

Interventions

DEVICE

No Results Yet

NCT04349267 | COMPLETED | PHASE1/PHASE2

44 participants

Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-07-14
Completion:: 2024-08-22

Conditions

Advanced Solid Tumor

Interventions

BIOLOGICAL

Results Available

NCT04331886 | COMPLETED

199 participants

An Observational Study of Patients With Coronavirus Disease 2019

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-04-13
Completion:: 2020-08-20

Conditions

COVID-19
Coronavirus

No Results Yet

NCT04323904 | RECRUITING

200 participants

Hantavirus Registry - HantaReg

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-03-04
Completion:: 2030-03-31

Conditions

Hantavirus Infections
Hemorrhagic Fever With Renal Syndrome
Nephropathia Epidemica
Hantavirus Cardiopulmonary Syndrome

Interventions

OTHER

No Results Yet

NCT04288674 | RECRUITING

200 participants

Leptospirosis Registry - LeptoScope

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-03-04
Completion:: 2030-02-28

Conditions

Leptospirosis

Interventions

OTHER

No Results Yet

NCT04280029 | ACTIVE_NOT_RECRUITING | NA

418 participants

SELUTION SLR™ 014 In-stent Restenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-07-06
Completion:: 2025-08-15

Conditions

Coronary Restenosis

Interventions

DEVICE

No Results Yet

NCT04257500 | COMPLETED | PHASE4

22 participants

Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-09-03
Completion:: 2025-08-22

Conditions

Polycystic Ovary Syndrome

Interventions

DRUG

No Results Yet

NCT04128761 | COMPLETED | NA

124 participants

Decreasing the Temporal Window in Individuals With Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-09-21
Completion:: 2024-05-28

Conditions

Alcohol Use Disorder

Interventions

BEHAVIORAL

Results Available

NCT04126824 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

28 participants

Effect of Addition of Steroids on Duration of Analgesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-01-06
Completion:: 2026-08-02

Conditions

Uterine Fibroids
Adenomyosis

Interventions

DRUG
OTHER

No Results Yet

NCT04109807 | SUSPENDED | NA

18 participants

Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-12-16
Completion:: 2027-08-31

Conditions

Asthma, Allergic

Interventions

OTHER

No Results Yet

NCT04091022 | COMPLETED | PHASE2

64 participants

Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2021-01-18
Completion:: 2025-12-11

Conditions

Non-melanoma Skin Cancer

Interventions

DRUG

No Results Yet

NCT04085445 | COMPLETED

500 participants

An "All-Comers" Study of the AgentTM MONORAILTM Paclitaxel-Coated PTCA Balloon Catheter Used in Real-World Clinical Practice in Chinese Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-11-13
Completion:: 2022-08-31

Conditions

Chinese Patients Treated With Agent DCB

Interventions

DEVICE

No Results Yet

NCT04082962 | COMPLETED | PHASE1

10 participants

Dexamethasone Implant for Retinal Detachment in Uveal Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-12-11
Completion:: 2023-12-07

Conditions

Exudative Retinal Detachment and Uveal Melanoma

Interventions

DRUG

No Results Yet

NCT04067115 | COMPLETED | PHASE1/PHASE2

37 participants

SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2021-01-05
Completion:: 2025-04-24

Conditions

Ewing Sarcoma

Interventions

DRUG
DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT04051502 | COMPLETED | EARLY_PHASE1

48 participants

ICG-Enabled Mapping of Ovarian Sentinel Lymph Nodes: A Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-08-05
Completion:: 2025-12-08

Conditions

Ovarian Cancer
Adnexal Mass

Interventions

DRUG

No Results Yet

NCT04050735 | COMPLETED | NA

76 participants

Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2021-05-19
Completion:: 2024-07-02

Conditions

HIV-1-infection
Alcohol Drinking

Interventions

OTHER

Results Available

NCT04045093 | ACTIVE_NOT_RECRUITING | PHASE4

370 participants

Dabigatran for Mitral Stenosis Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-10-22
Completion:: 2026-09-30

Conditions

Atrial Fibrillation
Mitral Stenosis

Interventions

DRUG

No Results Yet

NCT04009343 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

182 participants

Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-06-19
Completion:: 2020-08-24

Conditions

Uncomplicated Falciparum Malaria

Interventions

DRUG

No Results Yet

NCT03959098 | ACTIVE_NOT_RECRUITING

120 participants

Effectiveness and Safety of Korean Medicine Treatment for Cervical Disc Herniation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-06-24
Completion:: 2022-01-28

Conditions

Neck Pain
Cervical Radiculopathy
Intervertebral Disc Displacement

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03926052 | COMPLETED | PHASE3

61 participants

Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-08-07
Completion:: 2024-11-18

Conditions

Binge-Eating Disorder
Obesity

Interventions

DRUG

Results Available

NCT03860792 | COMPLETED | NA

84 participants

Therapeutic Diets in Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-10-15
Completion:: 2025-05-23

Conditions

Alzheimer Disease

Interventions

BEHAVIORAL

No Results Yet

NCT03758417 | TERMINATED | PHASE2

123 participants

A Study of LCAR-B38M CAR-T Cells, a Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Chinese Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-01-23
Completion:: 2025-07-10

Conditions

Multiple Myeloma

Interventions

BIOLOGICAL

No Results Yet

NCT03754790 | ACTIVE_NOT_RECRUITING | PHASE3

281 participants

Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-01-09
Completion:: 2026-11-05

Conditions

Hemophilia

Interventions

DRUG

No Results Yet

NCT03701581 | RECRUITING | PHASE2/PHASE3

70 participants

4-aminopyridine Treatment for Nerve Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2021-06-05
Completion:: 2027-07-31

Conditions

Nerve Injury
Prostate Cancer

Interventions

DRUG
OTHER

No Results Yet

NCT03696160 | COMPLETED | PHASE3

447 participants

The Late Presenter Treatment Optimisation Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-03-05
Completion:: 2024-06-17

Conditions

HIV/AIDS

Interventions

DRUG

Results Available

NCT03689400 | COMPLETED

19 participants

Changes of Pain and Functional Parameters in Back Pain Patients Over Time

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-10-11
Completion:: 2019-12-06

Conditions

Changes Over Time in Pain and Functional Parameters

Results Available

NCT03655678 | COMPLETED | PHASE2/PHASE3

59 participants

A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-09-14
Completion:: 2025-11-13

Conditions

Beta-Thalassemia
Thalassemia
Genetic Diseases, Inborn
Hematologic Diseases
Hemoglobinopathies

Interventions

BIOLOGICAL

No Results Yet

NCT03638167 | COMPLETED | PHASE1

11 participants

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2019-03-19
Completion:: 2023-12-22

Conditions

Central Nervous System Tumor, Pediatric
Glioma
Ependymoma
Medulloblastoma
Germ Cell Tumor
Atypical Teratoid/Rhabdoid Tumor
Primitive Neuroectodermal Tumor
Choroid Plexus Carcinoma
Pineoblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT03623464 | ACTIVE_NOT_RECRUITING | NA

107 participants

RCT of Mobile Apps & FitBit v. Usual Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-05-31
Completion:: 2026-06-30

Conditions

Pancreatic Cancer
Gastric Cancer
Hepatic Cancer
Colon Cancer
Rectal Cancer
Small Bowel Cancer

Interventions

OTHER

No Results Yet

NCT03567889 | RECRUITING | PHASE3

186 participants

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-09-20
Completion:: 2027-12-31

Conditions

Melanoma Stage IIIB
Melanoma Stage IIIC
Melanoma Stage IIID

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03534193 | TERMINATED | NA

28 participants

Effectiveness of Using Educational Modules Via Bedside Tablet in Newly Diagnosed Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-04-17
Completion:: 2019-04-30

Conditions

Type 1 Diabetes Mellitus

Interventions

OTHER

Results Available

NCT03500991 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-07-26
Completion:: 2024-01-17

Conditions

Central Nervous System Tumor, Pediatric
Glioma
Ependymoma
Medulloblastoma
Germ Cell Tumor
Atypical Teratoid/Rhabdoid Tumor
Primitive Neuroectodermal Tumor
Choroid Plexus Carcinoma
Pineoblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT03490929 | RECRUITING | PHASE4

146 participants

CEUS for Blunt Abdominal Trauma in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-06-01
Completion:: 2026-12-31

Conditions

Trauma Abdomen

Interventions

DRUG
DEVICE

No Results Yet

NCT03471130 | COMPLETED | PHASE1

48 participants

Definitive QT Study With MT-8554

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-04-23
Completion:: 2018-10-19

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT03381404 | COMPLETED | PHASE1

6 participants

Mass Balance Study With MT-8554

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-12-19
Completion:: 2018-01-29

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT03352687 | COMPLETED | NA

84 participants

Diaphragmatic Paralysis After Ultrasound Block of the Suprascapular Nerve for Shoulder Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2018-02-02
Completion:: 2019-01-28

Conditions

Surgery

Interventions

PROCEDURE

No Results Yet

NCT03317899 | COMPLETED | PHASE2

77 participants

Stem Cell Transplant With or Without Tbo-filgrastim in Treating Patients With Multiple Myeloma or Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-10-12
Completion:: 2021-06-01

Conditions

Non-Hodgkin's Lymphoma
Plasma Cell Myeloma

Interventions

PROCEDURE
DRUG
OTHER

Results Available

NCT03245892 | COMPLETED | PHASE1

27 participants

A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-08-04
Completion:: 2025-12-04

Conditions

High Grade Serous Ovarian
Fallopian Tube
Primary Peritoneal Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03215706 | COMPLETED | PHASE3

719 participants

A Study of Nivolumab and Ipilimumab Combined With Chemotherapy Compared to Chemotherapy Alone in First Line NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-08-24
Completion:: 2019-08-16

Conditions

Non-Small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

Results Available

NCT03077451 | COMPLETED | PHASE2

36 participants

Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2017-03-13
Completion:: 2022-05-23

Conditions

Recurrent Kaposi Sarcoma
Skin Kaposi Sarcoma

Interventions

OTHER
DRUG

Results Available