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Hantavirus Registry - HantaReg

NCT04323904 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-12-17

No results posted yet for this study

Summary

Hantavirus disease are zoonotic infections and remain a clinical challenge with globally increasing incidence and multiple serious outbreak situations in Europe within the last years. Hantavirus disease encompasses two clinical syndromes, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) caused by Old World and New World hantaviruses, respectively. Depending on the causative Old World hantavirus species, clinical course of HFRS can vary from mild to moderate to severe.

At present, there is no specific therapy available for hantavirus disease. As the clinical course of hantavirus disease is dependent on the causing viral pathogen and as there worrisome hints that clinical course HFRS and HCPS overlap, further studies with regard to the disease course are mandatory. Furthermore, the examination of attributable mortality and costs of hantavirus disease will need to be studied on a multinational basis and therefore HantaReg will particularly use a matched case control design.

Conditions

  • Hantavirus Infections
  • Hemorrhagic Fever With Renal Syndrome
  • Nephropathia Epidemica
  • Hantavirus Cardiopulmonary Syndrome

Interventions

OTHER

Retrospective data collection

Retrospective data collection from patients with hantavirus infection and matching control group patients.

Sponsors & Collaborators

  • University of Cologne

    lead OTHER

Principal Investigators

  • Volker Burst, MD · University Hospital of Cologne

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-04
Primary Completion
2030-03-31
Completion
2030-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04323904 on ClinicalTrials.gov