Clinical Trials Updated in 2025

NCT06416397 | RECRUITING

200 participants

Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile Biopsy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-04-08
Completion:: 2026-02-28

Conditions

Cholangiocarcinoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06409364 | RECRUITING | PHASE2

524 participants

FLudrocortisone Administration in Aneurysmal Subarachnoid Haemorrhage

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-08-13
Completion:: 2029-07-31

Conditions

Aneurysmal Subarachnoid Hemorrhage

Interventions

DRUG

No Results Yet

NCT06401694 | ENROLLING_BY_INVITATION | NA

1640 participants

Evaluating an Enhanced Home-delivered Meal Program on Older Adults' Health and Well-being

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-06-20
Completion:: 2027-09-30

Conditions

Diet, Healthy
Food Insecurity
Loneliness
Quality of Life

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06384911 | RECRUITING | NA

96 participants

InvesT1D: Promoting Adolescent Investment in Diabetes Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-06-25
Completion:: 2027-07-31

Conditions

Type 1 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT06384157 | COMPLETED | PHASE2

300 participants

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-06-10
Completion:: 2025-09-29

Conditions

Opioid Use Disorder

Interventions

DRUG
OTHER

No Results Yet

NCT06359314 | COMPLETED | NA

33 participants

Anxiety Lowering and Deprescribing Through Emotion Regulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-05-16
Completion:: 2024-09-05

Conditions

Benzodiazepine Dependence
Anxiety Disorders
Sleep Disturbance

Interventions

BEHAVIORAL

Results Available

NCT06345027 | NOT_YET_RECRUITING | PHASE1

12 participants

Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2026-02-28
Completion:: 2027-05-31

Conditions

Leukemia, Myeloid, Acute
Leukemia, B-cell
Leukemia, T-Cell

Interventions

BIOLOGICAL

No Results Yet

NCT06340763 | COMPLETED

12 participants

JETi Hong Kong Post Market Study (PMS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-08-07
Completion:: 2025-02-12

Conditions

Peripheral Venous Thrombosis
Peripheral Arterial Thrombosis
Peripheral Arteriovenous Thrombosis

Interventions

DEVICE

Results Available

NCT06297135 | COMPLETED | NA

52 participants

A Feasibility Study of a Support Program for Building New Parent-child Behavioral Habits

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-01
Completion:: 2025-03-31

Conditions

ADHD

Interventions

BEHAVIORAL

No Results Yet

NCT06294600 | RECRUITING | PHASE3

330 participants

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-12
Completion:: 2026-04-05

Conditions

Community-acquired Pneumonia

Interventions

DRUG

No Results Yet

NCT06293157 | RECRUITING | NA

226 participants

Carbon Fiber Transpedicular Screws in Treatment of Spinal Metastatic Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-12-01
Completion:: 2028-12-31

Conditions

Metastatic Spinal Cord Compression
Metastasis Spine

Interventions

PROCEDURE
RADIATION

No Results Yet

NCT06285500 | RECRUITING

400 participants

Umbrella Study for Single Patient Treatments in Oncology

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-01
Completion:: 2027-02-01

Conditions

Advanced Cancer
Rare Diseases

Interventions

OTHER

No Results Yet

NCT06243731 | RECRUITING

10 participants

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-11-03
Completion:: 2027-01-31

Conditions

Cytomegalovirus (CMV)
Kidney Disease
Kidney Failure

Interventions

OTHER

No Results Yet

NCT06237465 | WITHDRAWN | PHASE4

0 participants

Botulinum Toxin-A for Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-01-31
Completion:: 2025-06-30

Conditions

Hidradenitis Suppurativa
Hidradenitis Suppurativa \(HS\)
Hidradenitis Suppurativa, Acne Inversa

Interventions

DRUG

No Results Yet

NCT06215248 | RECRUITING

162 participants

Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-01
Completion:: 2026-12-31

Conditions

Peripheral Artery Disease
Heart Failure

No Results Yet

NCT06182969 | RECRUITING | PHASE1/PHASE2

40 participants

A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-08-09
Completion:: 2026-04-30

Conditions

SLE

Interventions

DRUG
OTHER

No Results Yet

NCT06120608 | ACTIVE_NOT_RECRUITING | NA

50 participants

Evidence for Potassium Restriction in Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-06-17
Completion:: 2026-03-12

Conditions

Hyperkalemia, Diminished Renal Excretion

Interventions

BEHAVIORAL

No Results Yet

NCT06116032 | RECRUITING

1500 participants

Immune Profiling for Cancer Immunotherapy Response

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-10-03
Completion:: 2027-01-01

Conditions

Cancer
Tumor, Solid
Hematologic Malignancy
Blood Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06109909 | RECRUITING | NA

36 participants

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-01-01
Completion:: 2026-11-30

Conditions

Mild Traumatic Brain Injury
Photophobia

Interventions

DEVICE

No Results Yet

NCT06109844 | COMPLETED

13 participants

FORCEREPAIR - A Wound Exudate Investigation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-01-24
Completion:: 2025-10-01

Conditions

Venous Leg Ulcer
Wound Healing
Non-healing Wound
Cytokines

Interventions

OTHER

No Results Yet

NCT06108050 | RECRUITING | PHASE1

177 participants

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-11-07
Completion:: 2027-11-30

Conditions

Advanced Solid Tumor
Metastatic Solid Tumor

Interventions

DRUG

No Results Yet

NCT06098404 | RECRUITING

250 participants

Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-03-04
Completion:: 2026-10-31

Conditions

Cancer

No Results Yet

NCT06096831 | ENROLLING_BY_INVITATION

240 participants

Living With Stroke - Sustainable Utilization of Healthcare Services

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-11-15
Completion:: 2026-03-31

Conditions

Stroke
Cerebrovascular Disorders
Cerebrovascular Accident
Healthcare Utilization

No Results Yet

NCT06084910 | RECRUITING | NA

134 participants

Self-Concept Reinforcement for Early School Readiness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-07-03
Completion:: 2028-11-30

Conditions

Child Behavior
Child Behavior Problem
Child Behavior Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06070857 | COMPLETED | PHASE1

81 participants

Study of the Safety, Tolerability, and Pharmacokinetics of LV232 Capsules in Chinese Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-10-05
Completion:: 2025-11-17

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT06054295 | RECRUITING

50 participants

Somatic Mosaicism in Twins Discordant for Childhood Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-06-03
Completion:: 2026-06-30

Conditions

Pediatric Central Nervous System Tumor
Central Nervous System Tumor
Discordant Twin
Somatic Mutation

Interventions

OTHER

No Results Yet

NCT06039176 | RECRUITING

150 participants

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-10-27
Completion:: 2026-12-30

Conditions

LVAD
Frailty
GI Bleed
Right Heart Failure
Infections
Hypertension
Arrhythmias
Stroke

Interventions

DEVICE

No Results Yet

NCT06037421 | RECRUITING

120 participants

Metagenomic Analysis of Bacterial Microbiota in Breast Milk

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2025-09-08
Completion:: 2028-12-31

Conditions

Bacteria in Breast Milk

Interventions

OTHER

No Results Yet

NCT06030089 | COMPLETED | NA

20 participants

Plasma Dosage of Venetoclax in the Fup of AML Patients Treated With Aza + Ven

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-26
Completion:: 2024-09-30

Conditions

Acute Myeloid Leukemia

Interventions

OTHER
DRUG

No Results Yet

NCT05998447 | TERMINATED | PHASE2

10 participants

GEN-001 Plus Pembrolizumab for Patients With Advanced Refractory Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-09-18
Completion:: 2024-11-26

Conditions

Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT05987709 | COMPLETED | NA

2004 participants

Study of Colorectal Cancer Screening Options

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-03-17
Completion:: 2022-12-31

Conditions

Colon Cancer

Interventions

DIAGNOSTIC_TEST

Results Available

NCT05982795 | RECRUITING

30 participants

Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-11-08
Completion:: 2026-12-01

Conditions

Cystic Fibrosis

Interventions

OTHER

No Results Yet

NCT05975268 | COMPLETED | PHASE3

747 participants

A Clinical Study to Evaluate the Efficacy and Safety of Subcutaneous JS005 Injection in the Treatment of Adults With Moderate to Severe Chronic Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-08-28
Completion:: 2025-08-20

Conditions

Moderate to Severe Chronic Plaque Psoriasis

Interventions

BIOLOGICAL

No Results Yet

NCT05901974 | RECRUITING | PHASE2

23 participants

Venetoclax Combined With Azactidine in the Treatment of ALAL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-07-01
Completion:: 2026-03-01

Conditions

Acute Leukemia of Ambiguous Lineage

Interventions

DRUG

No Results Yet

NCT05820997 | TERMINATED | PHASE4

2 participants

Paravertebral Block vs no Block in Open Pancreaticoduodenectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-04-24
Completion:: 2024-12-04

Conditions

Pancreaticoduodenectomy

Interventions

DRUG

Results Available

NCT05799287 | ACTIVE_NOT_RECRUITING | PHASE3

318 participants

A Study of Telitacicept for IgA Nephropathy (TELIGAN)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-04-28
Completion:: 2026-06-30

Conditions

Primary IgA Nephropathy

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05793853 | RECRUITING

106 participants

Hypoparathyroidism Natural History Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-08-25
Completion:: 2026-12-31

Conditions

Hypoparathyroidism

No Results Yet

NCT05745363 | COMPLETED | PHASE1/PHASE2

33 participants

Clinical Study of AL2846 Capsule in the Treatment of Differentiated Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-02-24
Completion:: 2025-11-13

Conditions

Differentiated Thyroid Cancer

Interventions

DRUG

No Results Yet

NCT05705024 | RECRUITING | PHASE2

38 participants

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-09-29
Completion:: 2026-09-28

Conditions

Corneal Ulcer

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05700747 | COMPLETED | NA

5 participants

Health Through Activity: A Pilot Study of a Rehabilitation Intervention for People Living With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2023-02-01
Completion:: 2025-03-28

Conditions

Multiple Myeloma

Interventions

BEHAVIORAL

Results Available