Clinical Trials Updated in 2025

NCT05894967 | RECRUITING | NA

1140 participants

Moderators and Mediators of Perceptual Learning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-04-14
Completion:: 2027-02-28

Conditions

Cognitive Change

Interventions

BEHAVIORAL

No Results Yet

NCT05891613 | COMPLETED | PHASE4

32 participants

A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-01-24
Completion:: 2025-10-06

Conditions

Breast Reduction

Interventions

DRUG

No Results Yet

NCT05885022 | RECRUITING | NA

60 participants

Feasibility Clinical Evaluation of the Calibreye System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-05-31
Completion:: 2027-12-31

Conditions

Glaucoma, Open-Angle

Interventions

DEVICE

No Results Yet

NCT05883462 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

45 participants

Paclitaxel-Coated Nasal Balloon for the Treatment of Recurrent Chronic Rhinosinusitis With or Without Nasal Polyps (FIH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-06-07
Completion:: 2025-10-21

Conditions

Chronic Rhinosinusitis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05866081 | RECRUITING | NA

792 participants

Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-06-01
Completion:: 2026-05-01

Conditions

Stone, Kidney
Stone Ureter

Interventions

DEVICE
OTHER

No Results Yet

NCT05823116 | COMPLETED | PHASE4

37 participants

Continuous vs. Intermittent Infusion Vancomycin

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-05-22
Completion:: 2025-06-15

Conditions

Vancomycin

Interventions

DRUG

No Results Yet

NCT05813288 | TERMINATED | PHASE3

654 participants

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-03-27
Completion:: 2025-12-08

Conditions

Eosinophilic Asthma
Asthma; Eosinophilic
Asthma

Interventions

DRUG

No Results Yet

NCT05803902 | COMPLETED | PHASE1

48 participants

An Evaluation of 9MW1911 Injection in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2021-12-15
Completion:: 2023-03-06

Conditions

Asthma
COPD
Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT05803460 | COMPLETED | NA

120 participants

Explore the Effects of Virtual Reality Natural Environment of Older People

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-04-07
Completion:: 2024-07-31

Conditions

Older People

Interventions

BEHAVIORAL

No Results Yet

NCT05798507 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

14 participants

Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-07-28
Completion:: 2026-12-03

Conditions

Glioblastoma
Recurrent Glioblastoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05796713 | COMPLETED

100 participants

Barriers to Patients' Early Presentation, Diagnosis and Treatment in Childhood Hydrocephalus

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-03-01
Completion:: 2024-01-27

Conditions

Hydrocephalus in Children

Interventions

OTHER

No Results Yet

NCT05763121 | TERMINATED | PHASE3

1061 participants

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-01-30
Completion:: 2025-12-08

Conditions

Eosinophilic Asthma
Asthma; Eosinophilic
Asthma

Interventions

DRUG

No Results Yet

NCT05716451 | COMPLETED | NA

40 participants

Pilot Study on Device-assisted Mobilisation of Critically Ill Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-04-27
Completion:: 2025-04-04

Conditions

Muscle Weakness
Critical Illness

Interventions

DEVICE

No Results Yet

NCT05681936 | RECRUITING

225 participants

Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-01-01
Completion:: 2027-08-31

Conditions

Spinal Cord Injuries
Neurogenic Bladder Dysfunction
Degenerative Cervical Spinal Stenosis

No Results Yet

NCT05672849 | RECRUITING | NA

100 participants

Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-11-14
Completion:: 2027-12-31

Conditions

Neural Tube Defects

Interventions

DEVICE

No Results Yet

NCT05666804 | COMPLETED | PHASE3

148 participants

Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-02-06
Completion:: 2025-09-10

Conditions

Macular Polypoidal Choroidal Vasculopathy (PCV)

Interventions

DRUG

No Results Yet

NCT05664594 | COMPLETED | NA

100 participants

State Representation in Early Psychosis - Project 4

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-07-31
Completion:: 2025-10-31

Conditions

Psychosis
Schizophrenia
Schizophrenia Spectrum and Other Psychotic Disorders
Schizoaffective Disorder

Interventions

DEVICE

No Results Yet

NCT05662982 | COMPLETED | NA

84 participants

Sub-Ischial Socket for Transfemoral Amputation and Lower Mobility

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-03-01
Completion:: 2025-11-30

Conditions

Transfemoral Amputation

Interventions

DEVICE

No Results Yet

NCT05627557 | ACTIVE_NOT_RECRUITING | PHASE3

85 participants

A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-03-29
Completion:: 2025-09-04

Conditions

Childhood Idiopathic Nephrotic Syndrome

Interventions

DRUG

No Results Yet

NCT05611671 | ACTIVE_NOT_RECRUITING | PHASE2

280 participants

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-11-21
Completion:: 2024-11-28

Conditions

Inflammatory Bowel Diseases
Colitis, Ulcerative

Interventions

DRUG

Results Available

NCT05603728 | RECRUITING

20000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2007-07-19
Completion:: 2030-12-31

Conditions

Osteo Arthritis Shoulders
Osteonecrosis
Rotator Cuff Tears
Rotator Cuff Tear Arthropathy
Ankylosing Spondylitis
Post-traumatic Osteoarthritis
Rheumatoid Arthritis
Fracture
Infections

No Results Yet

NCT05592782 | WITHDRAWN | NA

0 participants

VR Mindfulness Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-10-31
Completion:: 2023-10-31

Conditions

Anxiety
Depression
Stress
Pain, Acute
Pain, Chronic

Interventions

BEHAVIORAL

No Results Yet

NCT05590455 | RECRUITING | PHASE2

130 participants

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-04-11
Completion:: 2027-06-30

Conditions

Tuberculous Meningitis
HIV I Infection

Interventions

DRUG

No Results Yet

NCT05561361 | RECRUITING

200 participants

The Effect of SAAE on Vascular Endothelial Function in PA Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-10-01
Completion:: 2026-11-30

Conditions

Primary Aldosteronism

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05555355 | COMPLETED | PHASE4

104 participants

Prevena Spine for Use in Spine Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-12-01
Completion:: 2025-11-01

Conditions

Surgery
Incision, Surgical

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT05520281 | COMPLETED | NA

24 participants

Short-term Psychodynamic Psychotherapy in Serious Physical Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-09-15
Completion:: 2025-08-06

Conditions

Malignant Neoplasm
Carcinoma
Palliative Care

Interventions

BEHAVIORAL

No Results Yet

NCT05512819 | COMPLETED | PHASE3

541 participants

A Study to Describe the Safety and Immunogenicity of 20vPnC in Infants in India and Taiwan

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-09-16
Completion:: 2025-09-20

Conditions

Pneumococcal Disease

Interventions

BIOLOGICAL

No Results Yet

NCT05505851 | COMPLETED | NA

40 participants

Sequential Core Stability Corrective Exercise Approach in Lower Crossed Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-02-10
Completion:: 2025-12-01

Conditions

Low Back Pain

Interventions

OTHER

No Results Yet

NCT05493280 | COMPLETED | NA

15 participants

Fractionated 1927nm Laser for Hyperpigmentation in Fitzpatrick Skin Phototypes V and VI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-11-14
Completion:: 2024-07-26

Conditions

Hyperpigmentation

Interventions

DEVICE

Results Available

NCT05454358 | TERMINATED | PHASE2/PHASE3

12 participants

Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-08-02
Completion:: 2025-12-01

Conditions

Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05431972 | COMPLETED | NA

257 participants

Cardea SOLOTM for Paroxysmal Atrial Fibrillation Diagnosis in ESUS Patients With Left Atrial Enlargement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-11-01
Completion:: 2024-09-13

Conditions

Embolic Stroke of Undetermined Source

Interventions

DEVICE

No Results Yet

NCT05421676 | RECRUITING | NA

10 participants

Fetal Endoscopic Tracheal Occlusion for CDH (CDH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-02-12
Completion:: 2027-12-31

Conditions

Congenital Diaphragmatic Hernia

Interventions

DEVICE

No Results Yet

NCT05410418 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-10-24
Completion:: 2025-09-18

Conditions

Lymphoma, Follicular
Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT05374525 | COMPLETED | PHASE4

287 participants

A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-05-18
Completion:: 2024-08-08

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT05335434 | RECRUITING | NA

20 participants

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-06-10
Completion:: 2026-06-20

Conditions

Myeloablative Allogeneic Hematopoietic Cell Transplantation
Intraoral Photobiomodulation Therapy
Oral Mucositis
Mucosal Ulcer

Interventions

DEVICE

No Results Yet

NCT05317936 | TERMINATED | PHASE1/PHASE2

3 participants

Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-11-16
Completion:: 2025-10-06

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT05301361 | ENROLLING_BY_INVITATION | PHASE1

68 participants

Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-02-01
Completion:: 2026-09-29

Conditions

Intellectual Disability
Fragile X Syndrome
Down Syndrome
Attention Deficit Hyperactivity Disorder

Interventions

DRUG

No Results Yet

NCT05172024 | COMPLETED

15172 participants

Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2021-10-29
Completion:: 2025-10-31

Conditions

SARS-CoV2 Infection

No Results Yet

NCT05159700 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-03-31
Completion:: 2024-07-17

Conditions

Advanced Solid Tumor
Advanced Solid Malignancies

Interventions

DRUG

No Results Yet

NCT05158894 | RECRUITING

1884 participants

Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or Qulipta (Atogepant) During Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-01-10
Completion:: 2036-01-31

Conditions

Migraine

No Results Yet