Clinical Trials

NCT05131828 | COMPLETED | PHASE2

70 participants

CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2022-03-08

Completion:

2025-03-31

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05116384 | RECRUITING | NA

50 participants

Renal Denervation + PVI vs PVI Alone for Persistent AF

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2023-07-30

Completion:

2026-06-30

Conditions

• Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT05098197 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC101 TIL in Advanced Hepatobiliary-Pancreatic Cancers (10hospital)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-09-26

Completion:

2026-09-25

Conditions

• Advanced Liver Cancers
• Tumor Infiltrating Lymphocyte
• Treatment Side Effects
• Effects of Immunotherapy
• Advanced Pancreatic Cancers

Interventions

• BIOLOGICAL

No Results Yet

NCT05098184 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC101 TIL in Advanced Melanoma (10hospital)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-09-26

Completion:

2026-09-25

Conditions

• Advanced Melanoma
• Tumor Infiltrating Lymphocyte
• Treatment Side Effects
• Effects of Immunotherapy

Interventions

• BIOLOGICAL

No Results Yet

NCT05098171 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-09-26

Completion:

2026-09-25

Conditions

• Advanced Gynecologic Tumors
• Signal Switch Receptor Modified TIL
• Treatment Side Effects
• Effects of Immunotherapy

Interventions

• BIOLOGICAL

No Results Yet

NCT05063981 | COMPLETED

15 participants

Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-11

Start Date:

2021-11-25

Completion:

2023-09-29

Conditions

• Severe Eosinophilic Asthma

Interventions

• DRUG

No Results Yet

NCT05043025 | COMPLETED | NA

116 participants

Patient Positions for Locating the Cricothyroid Membrane

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2022-07-01

Completion:

2024-12-30

Conditions

• Cricothyroid Membrane

Interventions

• OTHER

No Results Yet

NCT05028712 | RECRUITING | NA

36 participants

Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2024-03-08

Completion:

2026-01-31

Conditions

• Low Vision Blindness
• Visual Impairment
• Quality of Life
• Functional Visual Loss

Interventions

• BEHAVIORAL

No Results Yet

NCT05026723 | RECRUITING | NA

200 participants

Food as Medicine for HIV and Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-10-04

Completion:

2026-08-31

Conditions

• Diabetes Mellitus, Type 2
• HIV Infections
• PreDiabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04941456 | COMPLETED | NA

26 participants

Does Endurance Improve With the Use of Passy-Muir Valve for Patients With Tracheostomy?

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-07-29

Completion:

2024-06-24

Conditions

• PMV
• Exercise Endurance
• Tracheostomy

Interventions

• OTHER
• DEVICE

Results Available

NCT04938206 | TERMINATED | NA

63 participants

DIStinguishing ChildrEn at Low Risk of Severe infectioN in Case of Febrile Neutropenia-7: Impact Study of a Clinical Decision Rule

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-01-27

Completion:

2024-10-10

Conditions

• Neutropenia, Febrile

Interventions

• PROCEDURE

No Results Yet

NCT04898543 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-06-21

Completion:

2026-05-31

Conditions

• Metastatic Solid Tumor

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04840888 | COMPLETED | PHASE1

82 participants

A Study of LY3484356 in Healthy Female Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-04-26

Completion:

2022-04-12

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT04823650 | COMPLETED

87 participants

Monitoring Activity And Gait In Children

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-11

Start Date:

2021-08-23

Completion:

2024-10-28

Conditions

• Child, Preschool
• Child
• Adolescent

Interventions

• DEVICE

Results Available

NCT04811027 | COMPLETED | PHASE2

171 participants

Combination Study With Eftilagimod Alpha (a Soluble LAG-3 Fusion Protein) and Pembrolizumab in Patients With Recurrent or Metastatic HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-08-27

Completion:

2024-03-11

Conditions

• HNSCC

Interventions

• DRUG

No Results Yet

NCT04798781 | COMPLETED | PHASE2

16 participants

Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-07-28

Completion:

2024-02-14

Conditions

• Gastric Cancer
• Hepatocellular Carcinoma

Interventions

• DRUG

Results Available

NCT04793685 | RECRUITING | PHASE2

150 participants

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-07-01

Completion:

2026-06-30

Conditions

• Alcohol Withdrawal

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT04752293 | RECRUITING

125 participants

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-11

Start Date:

2021-05-19

Completion:

2026-12-31

Conditions

• Hypertension
• Left Ventricular Hypertrophy
• Left Ventricular Dysfunction
• Left Atrial Dilatation
• Left Ventricular Diastolic Dysfunction
• Kidney Diseases
• Kidney Injury
• Kidney Dysfunction
• Sodium Urine High
• Blood Pressure Disorders
• Uric Acid Retention
• Angiotensin Hypertension
• Autonomic Dysfunction
• Autonomic Imbalance
• Pediatric Kidney Disease
• Pediatric Obesity
• Proteinuria
• Albuminuria

No Results Yet

NCT04742621 | RECRUITING

20 participants

Liver Transplantation for Unresectable Liver Limited Colorectal Metastases

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-11

Start Date:

2020-09-30

Completion:

2034-07-27

Conditions

• Unresectable Liver-limited Colorectal Metastases

Interventions

• PROCEDURE

No Results Yet

NCT04686786 | TERMINATED | PHASE2

105 participants

An Open-label Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-12-08

Completion:

2024-12-05

Conditions

• Seizures

Interventions

• DRUG

Results Available

NCT04665271 | COMPLETED | NA

453 participants

Acceptability and Efficacy of Zemedy App Versus Education and Relaxation Training App for IBS

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-03-01

Completion:

2023-12-30

Conditions

• Irritable Bowel Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT04540497 | ACTIVE_NOT_RECRUITING | PHASE3

135 participants

A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-12-04

Completion:

2024-04-09

Conditions

• IgG4 Related Disease

Interventions

• DRUG
• OTHER

Results Available

NCT04497428 | TERMINATED | NA

160 participants

Sensory Basis of Speech Motor Learning

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2019-08-01

Completion:

2025-07-31

Conditions

• Speech
• Consolidation

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04483466 | ACTIVE_NOT_RECRUITING | PHASE3

150 participants

Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2023-07-18

Completion:

2027-08-30

Conditions

• Investigate the Effect(s) of Methotrexate Treatment on Arthritis Disease Severity

Interventions

• DRUG

No Results Yet

NCT04402632 | COMPLETED | NA

600 participants

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-10-27

Completion:

2024-12-19

Conditions

• Subdural Hematoma

Interventions

• PROCEDURE
• DEVICE
• OTHER

No Results Yet

NCT04400591 | AVAILABLE

Nonconforming Lisocabtagene Maraleucel Expanded Access Protocol

Study Type:

EXPANDED_ACCESS

Last Updated:

2025-12-11

Conditions

• Lymphoma, Large B-Cell, Diffuse

Interventions

• BIOLOGICAL

No Results Yet

NCT04339166 | COMPLETED | NA

1152 participants

Embryo Selection by Noninvasive Preimplantation Genetic Test

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-04-16

Completion:

2024-02-28

Conditions

• Infertility
• Chromosome Abnormality

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04339140 | COMPLETED | PHASE2

5 participants

Zafirlukast in Treatment of Marker Relapsed Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-06-24

Completion:

2023-12-31

Conditions

• Ovarian Cancer

Interventions

• DRUG

Results Available

NCT04328805 | COMPLETED | PHASE4

123 participants

Ibuprofen and Neural Mobilization Treatment in Carpal Tunnel Syndrome.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-09-23

Completion:

2020-12-26

Conditions

• Carpal Tunnel Syndrome
• Ibuprofen
• Pain Management
• Pain, Chronic

Interventions

• DRUG
• OTHER

No Results Yet

NCT04319653 | TERMINATED | NA

1 participants

Development of a Pelvic Cavity Characterization Algorithm Through the Acquisition of MRI Images and Pressure Measurement by an Intravaginal Probe

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-04-13

Completion:

2021-05-13

Conditions

• Pelvic Floor Disorders

Interventions

• DEVICE

No Results Yet

NCT04246372 | COMPLETED | PHASE2

47 participants

Tofacitinib for Immune Skin Conditions in Down Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-10-21

Completion:

2024-10-30

Conditions

• Down Syndrome
• Alopecia Areata
• Atopic Dermatitis / Eczema
• Hidradenitis Suppurativa
• Vitiligo
• Psoriasis

Interventions

• DRUG

Results Available

NCT04207307 | COMPLETED | NA

404 participants

Best Function of Range of Motion (cRCT)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-11-03

Completion:

2023-08-04

Conditions

• Mobility

Interventions

• BEHAVIORAL

No Results Yet

NCT04191187 | COMPLETED | PHASE2

34 participants

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2019-12-06

Completion:

2024-02-11

Conditions

• Acute Myeloid Leukemia
• Acute Lymphoblastic Leukemia
• Biphenotypic Acute Leukemia
• Undifferentiated Leukemia
• Prolymphocytic Leukemia
• Myelodysplastic Syndromes
• Chronic Myelogenous Leukemia
• Myeloproliferative Neoplasm
• Relapsed Large Cell Lymphoma
• Mantle Cell Lymphoma
• Hodgkin Lymphoma
• Burkitt Lymphoma
• Relapsed T-Cell Lymphoma
• Relapsed Chronic Lymphocytic Leukemia
• Relapsed Small Lymphocytic Lymphoma
• Relapsed Marginal B-cell Lymphoma
• Relapsed Follicular Lymphoma
• Lymphoplasmacytic Lymphoma

Interventions

• DRUG
• RADIATION

Results Available

NCT04176497 | TERMINATED | PHASE2

8 participants

PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-07-16

Completion:

2024-02-07

Conditions

• Prostate Cancer

Interventions

• DRUG

Results Available

NCT04171323 | RECRUITING | NA

1305 participants

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2020-03-03

Completion:

2028-08-31

Conditions

• Age-related Cognitive Decline
• Mild Cognitive Impairment
• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT04157985 | COMPLETED | PHASE3

161 participants

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2019-11-15

Completion:

2025-10-14

Conditions

• Advanced Solid Tumors
• NSCLC
• Bladder Cancer
• HNSCC
• Renal Cancer
• Melanoma
• Anal Cancer
• Colorectal Cancer
• Cholangiocarcinoma
• Gastric Cancer
• Hepatocellular Carcinoma
• Merkel Cell Carcinoma
• Cervical Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT04154540 | COMPLETED | NA

67 participants

Posturography-Neuropathy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-05-19

Completion:

2024-01-19

Conditions

• Neuropathy Demyelinating

Interventions

• OTHER

No Results Yet

NCT04143295 | AVAILABLE

Rescue of Infants With MCT8 Deficiency

Study Type:

EXPANDED_ACCESS

Last Updated:

2025-12-11

Conditions

• Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency

Interventions

• DRUG

No Results Yet

NCT04137692 | SUSPENDED | NA

12 participants

Red Blood Cell Exchange Transfusion as a Novel Treatment for GLUT1 Deficiency Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2027-09-30

Completion:

2030-08-31

Conditions

• Glucose Transporter Type 1 Deficiency Syndrome
• GLUT1DS1

Interventions

• OTHER

No Results Yet

NCT04125862 | COMPLETED | NA

37 participants

Pain in Fibrous Dysplasia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-11

Start Date:

2021-01-05

Completion:

2025-12-01

Conditions

• Fibrous Dysplasia/McCune-Albright Syndrome

Interventions

• DIAGNOSTIC_TEST

No Results Yet