Clinical Trials Updated in 2025

NCT05291234 | COMPLETED | PHASE2

106 participants

A Study to Assess Safety of ABBV-916 and How Intravenous ABBV-916 Moves Through Body and Affects Brain Amyloid Plaque Clearance in Adult Participants (Aged 50-90 Years) With Early Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-15
Completion:: 2025-11-19

Conditions

Alzheimer's Disease (AD)

Interventions

DRUG

No Results Yet

NCT05289830 | TERMINATED | PHASE2

4 participants

Escitalopram to Placebo in Patients With Localized Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-05
Completion:: 2023-08-27

Conditions

Pancreatic Ductal Adenocarcinoma
Periampullary Cancer

Interventions

DRUG
OTHER

Results Available

NCT05215639 | COMPLETED

120 participants

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy in Switzerland and Austria Receiving Oral Venetoclax Tablets

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-12-27
Completion:: 2025-11-24

Conditions

Acute Myeloid Leukemia

No Results Yet

NCT05206084 | ACTIVE_NOT_RECRUITING | NA

518 participants

A Clinical Investigation to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-10
Completion:: 2024-12-29

Conditions

Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT05205499 | ACTIVE_NOT_RECRUITING | NA

1059 participants

A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-10
Completion:: 2024-07-01

Conditions

Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT05180175 | COMPLETED | PHASE4

300 participants

The Nordic IBD Treatment Strategy Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-02-07
Completion:: 2025-01-24

Conditions

Inflammatory Bowel Diseases
Ulcerative Colitis
Crohn Disease

Interventions

DRUG

No Results Yet

NCT05162573 | COMPLETED | PHASE1

14 participants

EBRT + Lu-PSMA for N1M0 Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-12-20
Completion:: 2025-09-09

Conditions

Prostatic Neoplasm

Interventions

DRUG
RADIATION

No Results Yet

NCT05161858 | COMPLETED

105 participants

Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary Dyskinesia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-29
Completion:: 2025-09-30

Conditions

Primary Ciliary Dyskinesia
Kartagener Syndrome

No Results Yet

NCT05145296 | TERMINATED | PHASE2

5 participants

The Safety/Efficacy Of Daratumumab With Belatacept In Highly HLA-Sensitized Patients Awaiting Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-01-19
Completion:: 2024-12-01

Conditions

Sensitisation
Highly Sensitised Dialysis Patients

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05062291 | ACTIVE_NOT_RECRUITING

500 participants

Merit WRAPSODY™ Endoprosthesis for Treatment of Stenosis or Occlusion (WRAP)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-06-23
Completion:: 2026-04-15

Conditions

Venous Stenosis
Venous Occlusion

Interventions

DEVICE

No Results Yet

NCT05061862 | ACTIVE_NOT_RECRUITING

1000 participants

Cardiac Implantable Electronic Device (CIED) Research Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-06
Completion:: 2025-10-31

Conditions

Arrhythmias, Cardiac
Bradycardia
Tachycardia

Interventions

DEVICE

No Results Yet

NCT04999267 | COMPLETED | NA

2 participants

Increasing Vaccine Uptake Among Adolescents in the Rural South

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-08-31
Completion:: 2022-11-03

Conditions

Vaccine Hesitancy

Interventions

OTHER

Results Available

NCT04955080 | COMPLETED

216 participants

REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-01-24
Completion:: 2025-09-01

Conditions

Pulmonary Disease, Chronic Obstructive
Exacerbation Copd
Comorbidities and Coexisting Conditions

No Results Yet

NCT04947904 | COMPLETED | NA

50 participants

OPTImized Restrictive Strategy Targeting Non-Resuscitative FLUIDs in Septic Shock: Pilot Study.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-09-20
Completion:: 2023-01-27

Conditions

Septic Shock
Electrolyte and Fluid Balance Conditions

Interventions

OTHER

No Results Yet

NCT04945655 | COMPLETED | NA

30739 participants

Impact of a School- and Primary Care-based Multicomponent Intervention on HPV Vaccination Acceptability

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-11-15
Completion:: 2022-06-30

Conditions

HPV Vaccine Acceptability

Interventions

OTHER

No Results Yet

NCT04931758 | COMPLETED

150 participants

Validation of the French Version of the Fremantle Back Awareness Questionnaire (FreBAQ) in Patients With Chronic Low Back Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-05-23
Completion:: 2023-04-28

Conditions

Low Back Pain

Interventions

OTHER

No Results Yet

NCT04919239 | COMPLETED | PHASE2

140 participants

Clinical Trial to Investigate Therapeutic Vaccine (RUTI) Against Tuberculosis (TB)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-09-22
Completion:: 2025-06-19

Conditions

Tuberculosis, Pulmonary

Interventions

BIOLOGICAL

No Results Yet

NCT04901884 | RECRUITING | NA

40 participants

PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-06-01
Completion:: 2026-06-01

Conditions

Pulmonary Hypertension

Interventions

DRUG

No Results Yet

NCT04841447 | RECRUITING

50 participants

Membrane Target Detection for Leukemia Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-03-20
Completion:: 2027-03-20

Conditions

Hematological Malignancy

Interventions

OTHER

No Results Yet

NCT04805320 | RECRUITING

25 participants

Association of Periodontal Inflammation on Immune Response in Wound Healing

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-09-01
Completion:: 2026-06-30

Conditions

Inflammation of Mouth

Interventions

PROCEDURE

No Results Yet

NCT04773470 | COMPLETED | NA

79 participants

Implementation of FEES in Spinal Muscle Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-02-01
Completion:: 2024-09-01

Conditions

Spinal Muscular Atrophy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04742374 | COMPLETED | EARLY_PHASE1

8 participants

Effects of Single Plasma Exchange and Double Filtration Plasmapheresis (DFPP) on Peripheral Lymphocyte Phenotypes in Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-03-12
Completion:: 2023-12-18

Conditions

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Interventions

BIOLOGICAL

No Results Yet

NCT04738162 | COMPLETED | PHASE2

78 participants

Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-09-25
Completion:: 2025-11-24

Conditions

Brain Tumor, Pediatric

Interventions

DRUG

No Results Yet

NCT04712747 | COMPLETED

91 participants

Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-01-25
Completion:: 2025-01-14

Conditions

Stroke

Interventions

PROCEDURE

No Results Yet

NCT04699539 | COMPLETED | NA

96 participants

Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-12-01
Completion:: 2025-08-16

Conditions

Treatment

Interventions

RADIATION
DRUG

Results Available

NCT04697849 | COMPLETED | NA

60 participants

Functional and Cognitive Rehabilitation of Hoarding Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-06-01
Completion:: 2025-08-01

Conditions

Hoarding Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04673461 | COMPLETED | PHASE2

110 participants

Study Investigating STA363 Compared to Placebo in Patients With Chronic Discogenic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-07-31
Completion:: 2023-09-01

Conditions

Discogenic Pain

Interventions

DRUG

No Results Yet

NCT04671615 | COMPLETED

559 participants

A Study to Understand the Treatment Patterns and Patients and Their Clinical Outcomes Who Are Taking Palbociclib in a Real Life Setting in Israel.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-12-06
Completion:: 2022-11-30

Conditions

Metastatic Breast Cancer

Interventions

DRUG

Results Available

NCT04578769 | RECRUITING | NA

52 participants

Assessment of Different Modified POEM for Achalasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-09-02
Completion:: 2025-12-30

Conditions

Esophageal Achalasia

Interventions

PROCEDURE

No Results Yet

NCT04566029 | COMPLETED

40 participants

Evolution of Proteomic Profiles of Intestinal Microbiota in Patients With Locally Advanced or Metastatic Urothelial Carcinomas

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-12-12
Completion:: 2022-11-29

Conditions

Urothelial Carcinoma

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT04511780 | COMPLETED

701 participants

Psychological Impact of COVID-19 Outbreak on Caregivers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-02-25
Completion:: 2022-07-20

Conditions

Critical Illness
Covid19
Stress Disorders, Post-Traumatic

Interventions

OTHER

No Results Yet

NCT04510506 | COMPLETED | NA

42 participants

Artificial Pancreas - Adolescent Physiology & Psychology Longitudinal Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-11-19
Completion:: 2025-10-23

Conditions

Type 1 Diabetes

Interventions

DEVICE

No Results Yet

NCT04478708 | COMPLETED | PHASE1

110 participants

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-08-07
Completion:: 2022-11-18

Conditions

Obesity

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04428541 | COMPLETED | NA

150 participants

Determination of the Validity of a Questionnaire to Assess the Visual Function of Preverbal Children With Operable Bilateral Ocular Pathologies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-07-16
Completion:: 2025-05-21

Conditions

Eye Diseases
Vision Disorders

Interventions

OTHER

No Results Yet

NCT04417699 | COMPLETED | PHASE2

13 participants

SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-07-05
Completion:: 2023-12-14

Conditions

Rectal Cancer

Interventions

DRUG

Results Available

NCT04392388 | COMPLETED

96883 participants

Health, Perception, Practices, Relations and Social Inequalities in the General Population During the Covid-19 Crisis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-05-01
Completion:: 2022-12-31

Conditions

SARS-CoV 2

Interventions

BIOLOGICAL

No Results Yet

NCT04381650 | COMPLETED | PHASE1/PHASE2

161 participants

A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-08-17
Completion:: 2024-10-29

Conditions

Advanced or Metastatic Solid Tumors

Interventions

DRUG

Results Available

NCT04351711 | COMPLETED

120 participants

Immunological Profiling of Patients With COVID-19 in Respiratory Distress

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-04-09
Completion:: 2022-12-12

Conditions

SARS-CoV-2
Covid-19

Interventions

OTHER

No Results Yet

NCT04349618 | COMPLETED | NA

220 participants

Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-04-15
Completion:: 2022-06-16

Conditions

Acute Respiratory Distress Syndrome
COVID19
Sars-CoV2
Pneumonia

Interventions

OTHER

No Results Yet

NCT04329247 | COMPLETED | NA

74 participants

Physical Therapy in the Treatment of Carpal Tunnel Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2020-05-05
Completion:: 2020-08-08

Conditions

Carpal Tunnel Syndrome

Interventions

OTHER

No Results Yet