Clinical Trials Updated in 2025

NCT05617911 | TERMINATED | NA

1 participants

Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-11-15
Completion:: 2023-10-10

Conditions

Patellofemoral Pain Syndrome
Anterior Knee Pain Syndrome

Interventions

DEVICE
PROCEDURE

Results Available

NCT05612789 | RECRUITING | NA

72 participants

Improve Outcomes for Older Allogeneic Transplant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-02-15
Completion:: 2030-06-01

Conditions

Allogeneic Transplantation

Interventions

BEHAVIORAL

No Results Yet

NCT05602363 | RECRUITING | PHASE1

120 participants

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-08-01
Completion:: 2027-09-30

Conditions

B-cell Malignancy
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Waldenstrom Macroglobulinemia
Mantle Cell Lymphoma
Marginal Zone Lymphoma
Follicular Lymphoma
Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05583110 | TERMINATED | PHASE2

13 participants

Efficacy and Safety of the Combination of Trastuzumab Plus TUCAtinib Plus viNorelbine in Patients With HER2-positive Non-resectable Locally Advanced or Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-03-08
Completion:: 2025-05-30

Conditions

HER2-positive Metastatic Breast Cancer
Locally Advanced HER2 Positive Breast Carcinoma

Interventions

DRUG

No Results Yet

NCT05570838 | TERMINATED | NA

70 participants

RAT and FES Effects on Upper Limb Motor Function in Subacute Stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-05-01
Completion:: 2024-12-01

Conditions

Motor Function

Interventions

DEVICE

No Results Yet

NCT05568888 | TERMINATED | PHASE3

1366 participants

Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-03-28
Completion:: 2024-10-29

Conditions

Traumatic Injury

Interventions

DRUG

Results Available

NCT05565144 | COMPLETED

15 participants

Brain Hemorrhage and Functional Outcome in Stroke Patients With CAA Features on Pre-thrombolysis MRI Treated With Intravenous Thrombolysis (Thrombolysis in CAA) ( Thromb in CAA )

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-10-02
Completion:: 2022-12-31

Conditions

Hemorrhage
Cerebral Amyloid Angiopathy
Stroke

Interventions

OTHER

No Results Yet

NCT05552547 | RECRUITING | NA

750 participants

Home BP Monitoring

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-10-01
Completion:: 2026-09-30

Conditions

High Blood Pressure

Interventions

DEVICE

No Results Yet

NCT05547633 | RECRUITING

200 participants

Detection and Management of Sinusitis in a Single-center Prospective Cohort of Patients With Exudative AMD (SINE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-01-20
Completion:: 2027-01-31

Conditions

AMD

Interventions

OTHER

No Results Yet

NCT05530863 | ENROLLING_BY_INVITATION | NA

20 participants

Behavioral Relaxation Approaches for Insomnia in Pregnant Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-04-01
Completion:: 2026-09-27

Conditions

Sleep Initiation and Maintenance Disorders
Pregnancy Related

Interventions

BEHAVIORAL

No Results Yet

NCT05521919 | COMPLETED | NA

38 participants

Acute Plasma Abeta Responses to Stress

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-12-05
Completion:: 2024-12-10

Conditions

Stress Reaction
Stress Physiology

Interventions

BEHAVIORAL

No Results Yet

NCT05484518 | COMPLETED | NA

6 participants

Method of Levels for People Using Community Crisis Services

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-09-06
Completion:: 2023-02-26

Conditions

Individuals Presenting to Crisis Services

Interventions

BEHAVIORAL

No Results Yet

NCT05471908 | RECRUITING | NA

2674 participants

Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-22
Completion:: 2027-02-28

Conditions

Pneumonia
Urinary Tract Infections
Soft Tissue Infections
Gastroenteritis

Interventions

BEHAVIORAL

No Results Yet

NCT05471557 | COMPLETED | NA

61 participants

Effects of Acute Pain on Motor Learning in Young vs Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-08-20
Completion:: 2025-06-05

Conditions

Aging
Pain, Acute
Cognitive Decline
Motor Activity

Interventions

PROCEDURE

No Results Yet

NCT05464381 | ACTIVE_NOT_RECRUITING | PHASE3

91 participants

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III, Cross-over)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-06-13
Completion:: 2025-08-29

Conditions

Epidermolysis Bullosa

Interventions

DRUG

No Results Yet

NCT05455112 | COMPLETED | PHASE2

41 participants

Safety and Efficacy of RUTI® With the Standard of Treatment for Tuberculosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-10-29
Completion:: 2024-10-30

Conditions

Tuberculosis, Pulmonary

Interventions

BIOLOGICAL

No Results Yet

NCT05432375 | COMPLETED | EARLY_PHASE1

10 participants

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-07-01
Completion:: 2024-11-10

Conditions

Glioblastoma Multiforme

Interventions

DRUG

No Results Yet

NCT05417750 | COMPLETED | PHASE1

43 participants

A Phase I Study of GC101 TIL in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-10-12
Completion:: 2025-04-30

Conditions

Tumor Infiltrating Lymphocytes
Safety
Advanced Solid Tumor
Immunotherapy
Efficacy
Adverse Drug Event

Interventions

DRUG

No Results Yet

NCT05416138 | COMPLETED | NA

26 participants

Theta Phase-specific TMS to Modulate Prefrontal Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-11-01
Completion:: 2024-08-31

Conditions

Approach/Avoidance Behavior

Interventions

DEVICE

Results Available

NCT05404854 | COMPLETED

89 participants

Evolution of Physical Activity, Sedentary Behavior and Associated Motivations After Rehabilitation for Chronic Low Back Pain Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-22
Completion:: 2023-11-20

Conditions

Chronic Low-back Pain

Interventions

OTHER

No Results Yet

NCT05363631 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-09-19
Completion:: 2026-12-31

Conditions

Clear Cell Renal Cell Carcinoma
Clear Cell Renal Cell Carcinoma Metastatic

Interventions

DRUG

No Results Yet

NCT05359367 | TERMINATED

6 participants

A Novel Approach to Enhance True Recovery After Stroke

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-11-29
Completion:: 2025-10-30

Conditions

Stroke
Inpatients
Recovery of Function
Observational Study

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05343299 | COMPLETED | PHASE1

91 participants

Postoperative Experience of 2 WALANT-type Modes of Anesthesia Used in Ambulatory Surgery of the Upper Limb.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-05-30
Completion:: 2023-06-25

Conditions

Anesthesia, Local
Hand Surgery
Wrist Surgery
Elbow Surgery

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05329337 | COMPLETED | NA

30 participants

Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-06-27
Completion:: 2022-10-05

Conditions

Insulin Resistance
Hyperinsulinism
Immune System

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05327166 | ACTIVE_NOT_RECRUITING | NA

500 participants

The Emergency Department Longitudinal Integrated Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-04-12
Completion:: 2026-05-31

Conditions

Opioid Use Disorder

Interventions

OTHER

No Results Yet

NCT05323864 | RECRUITING | NA

68 participants

Going to Altitude With Anxious-depressive Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-04-14
Completion:: 2025-07-15

Conditions

Hypoxia
Mental Disorder

Interventions

BIOLOGICAL

No Results Yet

NCT05291234 | COMPLETED | PHASE2

106 participants

A Study to Assess Safety of ABBV-916 and How Intravenous ABBV-916 Moves Through Body and Affects Brain Amyloid Plaque Clearance in Adult Participants (Aged 50-90 Years) With Early Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-15
Completion:: 2025-11-19

Conditions

Alzheimer's Disease (AD)

Interventions

DRUG

No Results Yet

NCT05289830 | TERMINATED | PHASE2

4 participants

Escitalopram to Placebo in Patients With Localized Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-08-05
Completion:: 2023-08-27

Conditions

Pancreatic Ductal Adenocarcinoma
Periampullary Cancer

Interventions

DRUG
OTHER

Results Available

NCT05215639 | COMPLETED

120 participants

A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy in Switzerland and Austria Receiving Oral Venetoclax Tablets

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-12-27
Completion:: 2025-11-24

Conditions

Acute Myeloid Leukemia

No Results Yet

NCT05206084 | ACTIVE_NOT_RECRUITING | NA

518 participants

A Clinical Investigation to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-10
Completion:: 2024-12-29

Conditions

Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT05205499 | ACTIVE_NOT_RECRUITING | NA

1059 participants

A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-10
Completion:: 2024-07-01

Conditions

Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT05180175 | COMPLETED | PHASE4

300 participants

The Nordic IBD Treatment Strategy Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-02-07
Completion:: 2025-01-24

Conditions

Inflammatory Bowel Diseases
Ulcerative Colitis
Crohn Disease

Interventions

DRUG

No Results Yet

NCT05162573 | COMPLETED | PHASE1

14 participants

EBRT + Lu-PSMA for N1M0 Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-12-20
Completion:: 2025-09-09

Conditions

Prostatic Neoplasm

Interventions

DRUG
RADIATION

No Results Yet

NCT05161858 | COMPLETED

105 participants

Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary Dyskinesia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-29
Completion:: 2025-09-30

Conditions

Primary Ciliary Dyskinesia
Kartagener Syndrome

No Results Yet

NCT05145296 | TERMINATED | PHASE2

5 participants

The Safety/Efficacy Of Daratumumab With Belatacept In Highly HLA-Sensitized Patients Awaiting Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-01-19
Completion:: 2024-12-01

Conditions

Sensitisation
Highly Sensitised Dialysis Patients

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05062291 | ACTIVE_NOT_RECRUITING

500 participants

Merit WRAPSODY™ Endoprosthesis for Treatment of Stenosis or Occlusion (WRAP)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-06-23
Completion:: 2026-04-15

Conditions

Venous Stenosis
Venous Occlusion

Interventions

DEVICE

No Results Yet

NCT05061862 | ACTIVE_NOT_RECRUITING

1000 participants

Cardiac Implantable Electronic Device (CIED) Research Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-03-06
Completion:: 2025-10-31

Conditions

Arrhythmias, Cardiac
Bradycardia
Tachycardia

Interventions

DEVICE

No Results Yet

NCT04999267 | COMPLETED | NA

2 participants

Increasing Vaccine Uptake Among Adolescents in the Rural South

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-08-31
Completion:: 2022-11-03

Conditions

Vaccine Hesitancy

Interventions

OTHER

Results Available

NCT04955080 | COMPLETED

216 participants

REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2022-01-24
Completion:: 2025-09-01

Conditions

Pulmonary Disease, Chronic Obstructive
Exacerbation Copd
Comorbidities and Coexisting Conditions

No Results Yet

NCT04947904 | COMPLETED | NA

50 participants

OPTImized Restrictive Strategy Targeting Non-Resuscitative FLUIDs in Septic Shock: Pilot Study.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2021-09-20
Completion:: 2023-01-27

Conditions

Septic Shock
Electrolyte and Fluid Balance Conditions

Interventions

OTHER

No Results Yet