Clinical Trials Updated in 2025

NCT05663216 | RECRUITING

180 participants

Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-31
Completion:: 2028-07-01

Conditions

Systemic Inflammatory Response Syndrome

Interventions

OTHER

No Results Yet

NCT05661019 | COMPLETED

56 participants

Clinical Feasibility of the Myotrace Measurement

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2024-05-15
Completion:: 2025-01-09

Conditions

Respiratory Disease

Interventions

OTHER

No Results Yet

NCT05650021 | COMPLETED | NA

17 participants

Rectal Spacer for Prostate Cancer Radiation Image Guidance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2024-03-08
Completion:: 2025-09-15

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT05646394 | RECRUITING

150 participants

Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-07-01
Completion:: 2029-07-31

Conditions

Antiphospholipid Syndrome
Arterial Thrombosis

Interventions

DRUG

No Results Yet

NCT05642481 | COMPLETED

16 participants

Therapeutic Drug Monitoring to oPtimize ANtiretroviral regimeNs in HIV-infected Women Who wAnt to Breastfeed

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-01
Completion:: 2025-12-01

Conditions

HIV-1-infection

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05642260 | RECRUITING | NA

90 participants

Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-08
Completion:: 2026-04-30

Conditions

Fall
Osteo Arthritis Knee
Total Knee Replacement

Interventions

OTHER

No Results Yet

NCT05633875 | RECRUITING

80 participants

Multimodal Imaging Signatures of the Biological Mechanisms Underlying Neurodegeneration in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-25
Completion:: 2026-06-25

Conditions

Multiple Sclerosis (MS)

Interventions

OTHER

No Results Yet

NCT05619653 | ACTIVE_NOT_RECRUITING | PHASE3

279 participants

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-12
Completion:: 2025-08-08

Conditions

COVID-19 Associated Cardiac Involvement
Remodeling, Left Ventricle
Remodeling, Vascular
Left Ventricular Dysfunction
Exercise Intolerance
Vascular Inflammation
Microvascular Angina
Long COVID
Myocarditis, Pericarditis

Interventions

DRUG

No Results Yet

NCT05595408 | RECRUITING

84 participants

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-02-01
Completion:: 2025-11-03

Conditions

Muscle Invasive Upper Tract Urothelial Carcinoma

Interventions

DRUG

No Results Yet

NCT05585749 | COMPLETED | NA

78 participants

Virtual Reality Application on Pain Intensity and Anxiety Level in Endoscopy Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-09-05
Completion:: 2023-01-30

Conditions

Anxiety

Interventions

OTHER

No Results Yet

NCT05579717 | COMPLETED | NA

40 participants

Examining the Effectiveness of EAL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-03-01
Completion:: 2025-08-31

Conditions

Trauma

Interventions

BEHAVIORAL

No Results Yet

NCT05567172 | COMPLETED | NA

43 participants

Watchman FLX Pro CT Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-24
Completion:: 2024-10-14

Conditions

Non-valvular Atrial Fibrillation (AF)

Interventions

DEVICE

Results Available

NCT05561400 | COMPLETED | NA

10 participants

Combining tDCS and CILT in Non-fluent Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-24
Completion:: 2023-12-15

Conditions

Aphasia
Non-fluent Aphasia
Stroke
Brain Injuries

Interventions

DEVICE
OTHER

Results Available

NCT05555680 | TERMINATED

32 participants

Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-01-21
Completion:: 2025-01-29

Conditions

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Interventions

OTHER

No Results Yet

NCT05555121 | SUSPENDED | PHASE2

150 participants

Rescue Progesterone Supplementation During Frozen Embryo Transfer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-01
Completion:: 2028-04-30

Conditions

Fertility Issues
Embryo Implantation
Frozen Embryo Transfer

Interventions

DRUG

No Results Yet

NCT05512754 | RECRUITING | PHASE4

200 participants

Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-08-01
Completion:: 2027-12-31

Conditions

Elevated Serum PSA

Interventions

DRUG

No Results Yet

NCT05500833 | RECRUITING

400 participants

Multidimensional Characterization of Dyspnea in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-26
Completion:: 2028-02-26

Conditions

Dyspnea and Respiratory Insufficiency in Children

Interventions

OTHER

No Results Yet

NCT05494593 | WITHDRAWN | PHASE4

0 participants

A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-28
Completion:: 2025-08-29

Conditions

Mucopolysaccharidosis (MPS)
Hunter Syndrome

Interventions

DRUG

No Results Yet

NCT05491213 | RECRUITING | NA

594 participants

TELESCOPE- TELEhealth Shared Decision-making COaching

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-14
Completion:: 2026-05-31

Conditions

Lung Neoplasms

Interventions

BEHAVIORAL

No Results Yet

NCT05477147 | COMPLETED | NA

96 participants

Re-Ablation Using a Tailored Approach Targeting EGM-Dispersion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-17
Completion:: 2025-05-07

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT05472142 | COMPLETED | NA

22 participants

Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-30
Completion:: 2024-10-30

Conditions

Diabetes

Interventions

OTHER

Results Available

NCT05446389 | TERMINATED | NA

33 participants

PAL to Improve Oral Feeding for Infants With Chronic Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-06-08
Completion:: 2025-04-24

Conditions

Chronic Lung Disease of Prematurity
Respiratory Distress Syndrome in Premature Infant
Bronchopulmonary Dysplasia
Preterm Birth

Interventions

DEVICE

No Results Yet

NCT05441709 | RECRUITING | NA

990 participants

Furthering Equity Through Infant Feeding EDucation and Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-11-08
Completion:: 2026-12-31

Conditions

Breastfeeding

Interventions

BEHAVIORAL

No Results Yet

NCT05391061 | RECRUITING

1100 participants

A Study to Learn About the Study Medicine (Called Cibinqo) in People With Atopic Dermatitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-07
Completion:: 2027-11-22

Conditions

Dermatitis, Atopic

Interventions

DRUG

No Results Yet

NCT05372497 | COMPLETED | NA

48 participants

Central Nervous System Focused Therapy in Frozen Shoulder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-05-11
Completion:: 2022-07-15

Conditions

Frozen Shoulder

Interventions

OTHER

No Results Yet

NCT05356364 | ACTIVE_NOT_RECRUITING | NA

100 participants

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-01
Completion:: 2026-04-30

Conditions

Insomnia
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05345717 | COMPLETED | PHASE1/PHASE2

5 participants

Novel Desensitization Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-05-01
Completion:: 2025-09-12

Conditions

Kidney Transplantation
End Stage Kidney Disease (ESRD)

Interventions

DRUG

No Results Yet

NCT05338658 | RECRUITING | PHASE1

21 participants

Study of PAT in Patients With Solid Tumor Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-19
Completion:: 2027-01-31

Conditions

Metastasis
Solid Tumor

Interventions

DRUG

No Results Yet

NCT05303428 | NOT_YET_RECRUITING | NA

80 participants

Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2026-10-31
Completion:: 2028-04-30

Conditions

Cognitive Change

Interventions

OTHER

No Results Yet

NCT05289947 | COMPLETED | PHASE2

303 participants

MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-07-21
Completion:: 2025-07-18

Conditions

Stroke
Stroke, Ischemic
Strokes Thrombotic
Stroke Sequelae
Stroke, Cardiovascular
Stroke, Embolic
Stroke, Cryptogenic

Interventions

OTHER
DRUG

No Results Yet

NCT05280379 | COMPLETED

33 participants

Trained Immunity in Thyroid Carcinoma and Colon Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-09-19
Completion:: 2025-05-01

Conditions

Thyroid Cancer, Nonmedullary
Colon Carcinoma

Interventions

OTHER

No Results Yet

NCT05252754 | RECRUITING | PHASE3

4874 participants

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-18
Completion:: 2026-12-31

Conditions

Post-ERCP Acute Pancreatitis

Interventions

DRUG

No Results Yet

NCT05241210 | SUSPENDED | NA

4150 participants

Real-Time Feedback (RTFB) to Improve Colonoscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-12-13
Completion:: 2026-12-31

Conditions

Colorectal Cancer

Interventions

DEVICE

No Results Yet

NCT05203510 | ACTIVE_NOT_RECRUITING | PHASE4

52 participants

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-10-20
Completion:: 2026-04-30

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

No Results Yet

NCT05192603 | ENROLLING_BY_INVITATION | NA

200 participants

Comparison Between Low FODMAP and SSRD in IBS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-03-01
Completion:: 2024-02-13

Conditions

IBS - Irritable Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05131919 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-22
Completion:: 2030-07-31

Conditions

Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05075200 | COMPLETED | PHASE2

21 participants

Tranexamic Acid Dosing for Major Joint Replacement Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-12-14
Completion:: 2022-10-26

Conditions

Arthroplasty, Replacement, Knee
Arthroplasty, Replacement, Hip

Interventions

DRUG

Results Available

NCT05031663 | COMPLETED | NA

61 participants

Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Older Men and Postmenopausal Women: A Randomized Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-08-12
Completion:: 2023-05-10

Conditions

Immune Response
Inflammation

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05028569 | TERMINATED | PHASE3

775 participants

Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-11-05
Completion:: 2024-11-06

Conditions

Episodic Migraine

Interventions

DRUG

Results Available

NCT05010460 | TERMINATED | PHASE2

98 participants

Study of Roxadustat for Reducing the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-09-30
Completion:: 2025-05-20

Conditions

Coronary Artery Bypass

Interventions

DRUG

No Results Yet