Clinical Trials Updated in 2025

NCT05439629 | COMPLETED | PHASE3

488 participants

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-07-07
Completion:: 2025-04-22

Conditions

Neovascular (Wet) Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT05434741 | COMPLETED | NA

50 participants

Cognitive Behavior Therapy (CBT)-Based Group Intervention to Reduce Inflammation in Older People With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-06-20
Completion:: 2023-12-01

Conditions

Aging
HIV

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05421442 | COMPLETED

38396 participants

A Post-marketing Study on the Safety of Abatacept Treatment in Denmark Using the Danish Database

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2019-06-13
Completion:: 2025-08-22

Conditions

Rheumatoid Arthritis (RA)
Psoriatic Arthritis (PsA)

No Results Yet

NCT05413044 | COMPLETED

140706 participants

A Post-marketing Study to Assess the Safety of Abatacept in Sweden Using the Swedish Rheumatology Quality Register (SRQ) Register

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2019-07-01
Completion:: 2025-08-22

Conditions

Rheumatoid Arthritis
Psoriatic Arthritis

No Results Yet

NCT05400590 | RECRUITING

24 participants

Comparison of the Healing Properties on Corneal Cells of Groth Factor-enriched Plasma and Autologous Serum From Aniridia Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-05-15
Completion:: 2026-05-31

Conditions

Aniridia

Interventions

PROCEDURE

No Results Yet

NCT05369520 | RECRUITING | NA

30 participants

Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-10-03
Completion:: 2026-10-31

Conditions

Spinal Cord Injury
Autonomic Dysfunction
Sexual Dysfunction
Neurogenic Bladder Dysfunction
Neurogenic Bowel Dysfunction
Autonomic Dysreflexia
Orthostatic Hypotension

Interventions

DEVICE

No Results Yet

NCT05337540 | COMPLETED | NA

120 participants

A Study to Evaluate the Efficacy, Safety and Tolerability of EVI-01 Intra-Articular Injection in Osteoarthritis of the Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-01-17
Completion:: 2025-10-29

Conditions

Osteoarthritis
Osteoarthritis, Knee

Interventions

DEVICE

No Results Yet

NCT05294419 | COMPLETED | NA

862 participants

The Healthcare Evaluation of Absolute Risk Testing Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-11-04
Completion:: 2022-08-31

Conditions

Cardiovascular Diseases

Interventions

DEVICE

Results Available

NCT05264818 | RECRUITING

100 participants

Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-05-06
Completion:: 2026-05-31

Conditions

Primary Open-angle Glaucoma
Glaucoma

Interventions

PROCEDURE

No Results Yet

NCT05263427 | COMPLETED | NA

60 participants

Maternal-Fetal Monitoring by Connected Abdominal Patch - MOMA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-08-31
Completion:: 2023-11-03

Conditions

Obstetrical Complications
Monitoring Injury of Scalp of Newborn

Interventions

DEVICE

No Results Yet

NCT05242835 | RECRUITING | NA

151 participants

Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-02-03
Completion:: 2027-01-31

Conditions

Obesity
Obesity, Morbid

Interventions

PROCEDURE

No Results Yet

NCT05215327 | RECRUITING | PHASE2

270 participants

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-11-08
Completion:: 2027-07-31

Conditions

Immunization; Infection
Transplantation Infection
Influenza

Interventions

BIOLOGICAL

No Results Yet

NCT05206500 | RECRUITING | PHASE4

100 participants

NextGen - Clinical Implication of Next Generation Sequencing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-05-17
Completion:: 2028-12-31

Conditions

Urinary Tract Infections

Interventions

DRUG
DEVICE

No Results Yet

NCT05198557 | ACTIVE_NOT_RECRUITING | PHASE3

80 participants

A Study of MT-0551 in Patients With Systemic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-07-20
Completion:: 2025-07-31

Conditions

Systemic Sclerosis

Interventions

DRUG

No Results Yet

NCT05173740 | RECRUITING | PHASE4

214 participants

Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-02-01
Completion:: 2027-07-31

Conditions

Cardiac Arrest
Heart Arrest
Cardiopulmonary Resuscitation
Return to Work
Return-to-work
Rehabilitation
Recovery of Function
Cardiac Rehabilitation

Interventions

OTHER

No Results Yet

NCT05170048 | NOT_YET_RECRUITING | PHASE2

90 participants

Study to Evaluate Safety and Efficacy of EG-301 in Patients With Nonfocal Geographic Atrophy Secondary to Dry-AMD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-06-30
Completion:: 2028-06-30

Conditions

Non-Exudative (Dry) Age-related Macular Degeneration (dAMD)

Interventions

DRUG
DIETARY_SUPPLEMENT

No Results Yet

NCT05155722 | COMPLETED | PHASE1

59 participants

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2020-09-17
Completion:: 2024-07-09

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05123066 | COMPLETED | NA

40 participants

Effect of Aquatic Training on Motor Function in Children With Autism Spectrum Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-01-01
Completion:: 2023-08-16

Conditions

Autism Spectrum Disorder

Interventions

OTHER

No Results Yet

NCT05108649 | COMPLETED | NA

74 participants

Impact of Nicotine Messaging on Beliefs and Behavior

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-03-02
Completion:: 2024-06-20

Conditions

Smoking Behaviors
Cigarette Smoking

Interventions

OTHER

Results Available

NCT05106127 | NOT_YET_RECRUITING | PHASE2

28 participants

Safety Lead-In Study of a Repurposed Drug Added to the Combination of Len Plus Pem

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-08-31
Completion:: 2027-03-31

Conditions

Advanced Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05105971 | COMPLETED | PHASE1

30 participants

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumor Patients in China

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-12-23
Completion:: 2023-11-14

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT05105919 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

50 participants

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-08-26
Completion:: 2024-04-01

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT05089370 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

8 participants

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-06-20
Completion:: 2026-08-31

Conditions

Malignant Melanoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05077215 | NOT_YET_RECRUITING | PHASE3

450 participants

Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-12-31
Completion:: 2027-12-31

Conditions

Advanced Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05072977 | TERMINATED | NA

71 participants

Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-02-09
Completion:: 2023-06-05

Conditions

Myopia
Astigmatism

Interventions

PROCEDURE

No Results Yet

NCT05053139 | COMPLETED | PHASE3

281 participants

A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-12-02
Completion:: 2024-03-11

Conditions

Haemophilia A
Haemophilia A With Inhibitors

Interventions

DRUG

No Results Yet

NCT05028140 | RECRUITING | PHASE3

480 participants

Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-10-08
Completion:: 2026-07-31

Conditions

Type II Diabetes

Interventions

DRUG
OTHER

No Results Yet

NCT04988477 | COMPLETED | PHASE2

94 participants

Proactive Outreach for Smoking Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-07-14
Completion:: 2022-12-06

Conditions

Smoking, Tobacco
Mental Illness

Interventions

BEHAVIORAL

Results Available

NCT04947553 | COMPLETED | PHASE3

456 participants

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-06-17
Completion:: 2024-12-03

Conditions

Agitation in Patients With Dementia of the Alzheimer's Type
Alzheimer Disease
Agitation, Psychomotor

Interventions

DRUG

No Results Yet

NCT04944030 | RECRUITING | NA

200 participants

Clinico-biological Data Collection Study of Metastatic Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-04-24
Completion:: 2031-10-31

Conditions

Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT04944017 | COMPLETED | PHASE2

51 participants

Ketamine for the Treatment of Depression in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-11-23
Completion:: 2025-09-24

Conditions

Parkinson's Disease
Depression

Interventions

DRUG
OTHER

No Results Yet

NCT04936607 | RECRUITING | NA

1158 participants

ImproviNg rEnal Outcomes Following Coronary angiograPhy and/or percuTaneoUs coroNary intErventions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-06-28
Completion:: 2027-01-30

Conditions

Contrast-Induced Acute Kidney Injury

Interventions

PROCEDURE

No Results Yet

NCT04932980 | ACTIVE_NOT_RECRUITING | NA

80 participants

Comparison of Rapid Aflibercept and Brolucizumab T&E in wAMD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-05-09
Completion:: 2027-06-30

Conditions

Wet Age-related Macular Degeneration

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04882878 | COMPLETED | PHASE2

228 participants

A Study of Nipocalimab in Adult Participants With Active Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-08-20
Completion:: 2024-04-30

Conditions

Systemic Lupus Erythematosus

Interventions

OTHER
DRUG

No Results Yet

NCT04877379 | COMPLETED | PHASE1

53 participants

VNRX-7145 Drug-Drug Interaction in Healthy Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-06-08
Completion:: 2021-11-10

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT04794634 | COMPLETED | NA

55 participants

Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2021-01-13
Completion:: 2023-06-23

Conditions

Optical Coherence Tomography
Optical Coherence Tomography Angiography
Retinal Thickening
Alzheimer Disease
Lewy Body Disease
Retina
Cortical Atrophy
Retinal Nerve Fibres Layer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04767555 | ACTIVE_NOT_RECRUITING | NA

250 participants

Impact of ILM Peeling in RRD/ I-Peel

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-02-23
Completion:: 2026-04-30

Conditions

Retinal Detachment

Interventions

PROCEDURE

No Results Yet

NCT04759885 | COMPLETED | PHASE2/PHASE3

886 participants

Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2020-06-18
Completion:: 2021-07-16

Conditions

Elective Colonoscopy

Interventions

DRUG

Results Available

NCT04684914 | TERMINATED | PHASE2

87 participants

HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2020-12-26
Completion:: 2024-03-27

Conditions

Hepatitis B, Chronic

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04670666 | RECRUITING | PHASE3

270 participants

Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-11-18
Completion:: 2026-07-31

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG
OTHER

No Results Yet