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Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury

NCT05369520 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-12-08

No results posted yet for this study

Summary

This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of individuals with spinal cord injury (SCI).

Conditions

  • Spinal Cord Injury
  • Autonomic Dysfunction
  • Sexual Dysfunction
  • Neurogenic Bladder Dysfunction
  • Neurogenic Bowel Dysfunction
  • Autonomic Dysreflexia
  • Orthostatic Hypotension

Interventions

DEVICE

TESCoN or SCONE device - Thoracic stimulation

TCSCS will be delivered using a non-invasive central nervous system stimulator (TESCoN or SCONE, SpineX Inc., CA, USA). The stimulation site will be over the thoracic spinal cord.

DEVICE

TESCoN or SCONE device - Lumbosacral stimulation

TCSCS will be delivered using a non-invasive central nervous system stimulator (TESCoN or SCONE, SpineX Inc., CA, USA). The stimulation site will be over the lumbosacral spinal cord.

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • Congressionally Directed Medical Research Programs

    collaborator FED

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Andrei Krassioukov, MD, PhD, FRCPC · The University of British Columbia, International Collaboration on Repair Discoveries (ICORD)

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-03
Primary Completion
2026-10-31
Completion
2027-10-31
FDA Device
Yes

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05369520 on ClinicalTrials.gov