Clinical Trials Updated in 2025

NCT06680427 | ACTIVE_NOT_RECRUITING | NA

30 participants

Siegel™ Transcatheter Aortic Valve Replacement System (TAVR) Early Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2025-03-26
Completion:: 2025-12-31

Conditions

Aortic Stenosis Symptomatic

Interventions

DEVICE

No Results Yet

NCT06661733 | COMPLETED | PHASE1

16 participants

A Study to Investigate the Pharmacokinetics, Safety and Tolerability of AZD5462 in Participants With Renal Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-18
Completion:: 2024-12-23

Conditions

Renal Impairment

Interventions

DRUG

No Results Yet

NCT06658067 | RECRUITING | NA

17 participants

Continuous Glucose Monitors (CGMs) for All: Studying the Impact of Expanding CGM Access

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-12
Completion:: 2026-06-30

Conditions

Diabetes
Type 2 Diabetes
Type 2 Diabetes Mellitus - Poor Control

Interventions

DEVICE

No Results Yet

NCT06645678 | RECRUITING | PHASE1/PHASE2

75 participants

Mezigdomide and Elranatamab for Relapsed and/or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-26
Completion:: 2026-10-01

Conditions

Relapsed Refractory Multiple Myeloma (RRMM)

Interventions

DRUG

No Results Yet

NCT06641180 | COMPLETED | PHASE3

1180 participants

Study to Evaluate Immunogenicity and Safety of a High-Dose Influenza Vaccine in Adults 50 Through 64 Years of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-04
Completion:: 2025-01-28

Conditions

Influenza

Interventions

BIOLOGICAL

No Results Yet

NCT06639295 | ACTIVE_NOT_RECRUITING | PHASE3

243 participants

A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-22
Completion:: 2025-12-31

Conditions

Sinusitis
Nasal Polyps

Interventions

DRUG

No Results Yet

NCT06623578 | RECRUITING | NA

876 participants

Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-09-23
Completion:: 2033-12-31

Conditions

Papillary Thyroid Carcinoma
Lymphatic Metastasis

Interventions

PROCEDURE

No Results Yet

NCT06617312 | RECRUITING | PHASE2

64 participants

Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-12-05
Completion:: 2026-12-31

Conditions

Smoking Cessation
Tobacco Use Disorder

Interventions

DRUG

No Results Yet

NCT06610890 | COMPLETED | PHASE1

20 participants

Pharmacokinetic Interactions Between Hemay005 Tablets and Midazolam Maleate Tablets

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-12-12
Completion:: 2025-01-20

Conditions

Psoriasis

Interventions

DRUG

No Results Yet

NCT06608121 | COMPLETED | NA

32 participants

Upper Limb Muscle Strength Models for Patients With Motor Impairment.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-05
Completion:: 2025-10-22

Conditions

Stroke
Multiple Sclerosis
Spinal Cord Injuries

Interventions

OTHER

No Results Yet

NCT06583135 | COMPLETED | NA

40 participants

Effect of Motivational Interviewing on Sleep Hygiene, Sleep Quality and Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-08-10
Completion:: 2025-02-10

Conditions

Sleep Hygiene

Interventions

OTHER

No Results Yet

NCT06548165 | ACTIVE_NOT_RECRUITING | NA

36 participants

Physiological Reaction After Food Intake

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-12
Completion:: 2025-08-14

Conditions

Physiological Reactivity to Cues

Interventions

DEVICE

No Results Yet

NCT06545721 | RECRUITING | NA

425 participants

Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-08-13
Completion:: 2026-03-01

Conditions

Polycystic Ovary Syndrome

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06518486 | COMPLETED | NA

375 participants

Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-10-04
Completion:: 2025-01-15

Conditions

Diabetic Foot
Diabetes Mellitus, Type 2
Diabetic Neuropathies
Diabetes Type 2
Diabetes
Diabetes Mellitus
Diabetes Complications

Interventions

OTHER

No Results Yet

NCT06485076 | RECRUITING | NA

144 participants

Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-07-18
Completion:: 2026-12-31

Conditions

Multiple Myeloma in Relapse
Multiple Myeloma, Refractory
Multiple Myeloma Stage III
Multiple Myeloma Progression
Multiple Myeloma
B Cell Lymphoma
Lymphoma, B-Cell
Aggressive Lymphoma

Interventions

OTHER

No Results Yet

NCT06476834 | COMPLETED | PHASE4

8 participants

A Study Evaluating Deucravacitinib Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-06-24
Completion:: 2024-11-02

Conditions

Healthy Volunteers

Interventions

DRUG

Results Available

NCT06470919 | COMPLETED | NA

3522 participants

The Next Generation Vaccine Card: Innovative Technology to Improve Vaccine Equity in Rural and Urban Settings in East Africa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-06
Completion:: 2025-10-29

Conditions

Vaccines

Interventions

OTHER

No Results Yet

NCT06445231 | RECRUITING | NA

1050 participants

Echocardiography in Nursing Home

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-10-02
Completion:: 2028-01-01

Conditions

Heart Diseases
Heart Failure
Heart Valve Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06438302 | RECRUITING

22 participants

Effects of Nasal Ventilation on Cerebral and Pulmonary Function in Orally Intubated Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2025-01-31
Completion:: 2028-02-01

Conditions

Hypoxemic Acute Respiratory Failure

Interventions

DEVICE

No Results Yet

NCT06429254 | COMPLETED | NA

64 participants

The Effect of Emotional Freedom Techniques on Pelvic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-05-24
Completion:: 2024-10-27

Conditions

Woman
Pelvic Pain

Interventions

OTHER

No Results Yet

NCT06426693 | RECRUITING | NA

50 participants

Craving Network Neurofeedback

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-11-27
Completion:: 2027-03-31

Conditions

Overweight or Obesity

Interventions

DEVICE

No Results Yet

NCT06416020 | NOT_YET_RECRUITING | NA

400 participants

Integrating MOUD in Nonmedical Community Settings (Better Together)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2026-01-26
Completion:: 2028-07-31

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06388668 | RECRUITING

100 participants

Lipid Testing After Myocardial Infarction at the Montreal Heart Institute

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-06-01
Completion:: 2026-03-31

Conditions

Dyslipidemias
Lipid Testing
Myocardial Infarction

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06375837 | ACTIVE_NOT_RECRUITING | NA

33 participants

Comparative Evaluation of an Alkasite-based Restorative Material and Two Different Resin Composites

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-04-15
Completion:: 2024-06-15

Conditions

Tooth Diseases

Interventions

DEVICE

No Results Yet

NCT06373601 | RECRUITING | NA

140 participants

SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-09-05
Completion:: 2027-08-01

Conditions

Coronary Artery Disease
Stenosis Coronary
Coronary Artery Lesion
Percutaneous Coronary Intervention

Interventions

DEVICE

No Results Yet

NCT06372847 | RECRUITING | NA

58 participants

DISE-HNS Effect Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2025-10-21
Completion:: 2028-03-31

Conditions

Obstructive Sleep Apnea

Interventions

DEVICE
DIAGNOSTIC_TEST
PROCEDURE

No Results Yet

NCT06363357 | RECRUITING | NA

30 participants

The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-04-20
Completion:: 2025-12-31

Conditions

Muscular Dystrophy, Duchenne
Orthotic Devices
Upper Extremity
Neuromuscular Diseases (NMD)
Fascioscapulohumeral Muscular Dystrophy
Spinal Muscular Atrophy (SMA)
ALS (Amyotrophic Lateral Sclerosis)
LGMD
SCI - Spinal Cord Injury

Interventions

DEVICE

No Results Yet

NCT06360458 | ACTIVE_NOT_RECRUITING | PHASE3

928 participants

Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-08-01
Completion:: 2025-09-30

Conditions

Acute Ischemic Stroke
Large Infarct Core

Interventions

DRUG

No Results Yet

NCT06345768 | COMPLETED | NA

90 participants

The Effect of the Stress Ball Applied Before Colocystectomy Surgery on Patients; Surgical Fear, Anxiety and Comfort.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-03-27
Completion:: 2024-10-30

Conditions

Cholecystitis
Stress
Fear
Comfort

Interventions

OTHER

No Results Yet

NCT06302595 | RECRUITING | NA

15 participants

MRI Guided Prostate Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2023-08-24
Completion:: 2026-06-30

Conditions

Suspected Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT06299839 | RECRUITING | PHASE1

48 participants

PAS-004 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-02-29
Completion:: 2026-02-28

Conditions

RAS Mutation
NF1 Mutation
RAF Mutation
Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06282055 | RECRUITING

350 participants

Trajectories in Insulin Sensitivity Across MEnstrual cycleS in Women With Type 1 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2025-11-20
Completion:: 2027-09-15

Conditions

Diabetes Mellitus, Type 1

Interventions

OTHER

No Results Yet

NCT06260904 | COMPLETED | PHASE4

64 participants

Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-01-26
Completion:: 2025-10-30

Conditions

Oral Lichen Planus

Interventions

DRUG

No Results Yet

NCT06257160 | COMPLETED | NA

224 participants

Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-05-22
Completion:: 2025-09-18

Conditions

Hip Arthropathy
Hip Arthrosis

Interventions

PROCEDURE

No Results Yet

NCT06246214 | RECRUITING | NA

150 participants

From Prevention to Treatment: How Biological Rhythms Can Maintain Perinatal Mental Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-01-04
Completion:: 2027-05-31

Conditions

Depression, Postpartum
Anxiety State

Interventions

DEVICE

No Results Yet

NCT06237803 | RECRUITING

6000 participants

European Myeloma Network (EMN) Sample Project

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2022-12-21
Completion:: 2037-12-31

Conditions

Multiple Myeloma
Smoldering Multiple Myeloma
Plasma Cell Leukemia
Extramedullary Myeloma
MGUS

Interventions

OTHER

No Results Yet

NCT06228365 | RECRUITING | NA

400 participants

Minimally Invasive Superficial Venous Insufficiency Surgery and Digital Sedation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2023-11-20
Completion:: 2026-05-31

Conditions

Superficial Venous Insufficiency

Interventions

DEVICE
DRUG

No Results Yet

NCT06225050 | NOT_YET_RECRUITING | NA

18 participants

M-2018-334 in Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2026-02-28
Completion:: 2029-02-28

Conditions

Hematological Malignancies

Interventions

DEVICE

No Results Yet

NCT06209567 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

11 participants

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-01-05
Completion:: 2027-01-05

Conditions

High-grade Glioma
Brain Metastases
Brain Metastases, Adult

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06209307 | ACTIVE_NOT_RECRUITING | NA

72 participants

Pelvic Floor Physical Therapy to Reduce Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2024-02-08
Completion:: 2026-03-31

Conditions

Prostatic Hyperplasia
Stress Urinary Incontinence

Interventions

BEHAVIORAL

No Results Yet