Clinical Trials Updated in 2025

NCT07257835 | RECRUITING

20 participants

Dupilumab Therapy for EGIDs

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-01-01
Completion:: 2027-01-01

Conditions

Eosinophilic Gastrointestinal Disorders (EGIDs)

Interventions

DRUG
DEVICE

No Results Yet

NCT07257809 | RECRUITING | PHASE2

56 participants

Herombopag Treated T-DM1 Induced Platelet Reduction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-10-13
Completion:: 2026-09-26

Conditions

Thrombocytopenia

Interventions

DRUG

No Results Yet

NCT07257796 | RECRUITING

3000 participants

Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-11-01
Completion:: 2027-05-31

Conditions

Intestinal Metaplasia of Gastric Mucosa
Artificial Intelligence
Endoscopy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07257783 | COMPLETED | NA

46 participants

Effect of Buteyko Breathing Exercise Combined With Postural Stability Exercises on Maximal Oxygen Consumption in Young Adult Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-07-20
Completion:: 2024-12-01

Conditions

Smoking ( Cigarette)

Interventions

OTHER

No Results Yet

NCT07257757 | COMPLETED

60 participants

Fascia Iliaca Compartment Block in Total Knee Arthroplasty With Intra-Articular Injection

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-06-05
Completion:: 2025-01-15

Conditions

Total Knee Arthroplasty (Postoperative Pain)

No Results Yet

NCT07257744 | RECRUITING

90 participants

Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-02-15
Completion:: 2025-12-20

Conditions

Chronic Postoperative Pain
Open Heart Surgery
Postoperative Analgesia
Analgesia

Interventions

OTHER

No Results Yet

NCT07257731 | COMPLETED | NA

57 participants

The Effect of Reformer Pilates on Functional Capacity, Balance, and Quality of Life in Sedentary Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-05-15
Completion:: 2025-06-15

Conditions

Sedentary Lifestyle
Functional Capacity

Interventions

BEHAVIORAL

No Results Yet

NCT07257718 | NOT_YET_RECRUITING | PHASE2

262 participants

The Combined Role of FAPI PET and Liquid Biopsy in the Staging and Clinical Management of Bladder Cancer - FUTURE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2026-09-30
Completion:: 2027-09-30

Conditions

Bladder Cancer

Interventions

PROCEDURE

No Results Yet

NCT07257679 | RECRUITING | PHASE4

36 participants

Gentle Touch for Post-Mastectomy Lymphedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-11-01
Completion:: 2027-01-15

Conditions

Lymphedema, Breast Cancer

Interventions

OTHER

No Results Yet

NCT07257653 | RECRUITING | PHASE2

70 participants

The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-10-21
Completion:: 2026-12-31

Conditions

Colorectal Neoplasms
RAS
BRAF
Cetuximabβ
Fruquintinib

Interventions

DRUG

No Results Yet

NCT07257627 | COMPLETED | PHASE1

27 participants

Comparative PK/PD of Single-Dose THDB0206 at Different Injection Sites

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-04-17
Completion:: 2024-12-02

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT07257588 | ENROLLING_BY_INVITATION | NA

44 participants

The Efficacy of Hyperbaric Oxygen-assisted Treatment for ASUC and Refractory IBD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-09-30
Completion:: 2025-12-31

Conditions

Ulcerative Colitis

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07257575 | ACTIVE_NOT_RECRUITING | PHASE2

138 participants

A Randomized Controlled Study of Serplulimab Combined With Chemotherapy for Locally Advanced Gastric Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-01-05
Completion:: 2027-01-31

Conditions

Gastric Cancer Stage III

Interventions

DRUG

No Results Yet

NCT07257562 | RECRUITING

40 participants

Combined Use of Bacteroides Fragilis and BCAAs on HBsAg Clearance

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-06-01
Completion:: 2026-03-01

Conditions

Chronic Hepatitis B

Interventions

DRUG

No Results Yet

NCT07257549 | COMPLETED | NA

40 participants

Real-Time Non-Invasive Localization for Multiple Lung Nodules

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-07-01
Completion:: 2025-05-01

Conditions

Lung Cancer (NSCLC)

Interventions

PROCEDURE

No Results Yet

NCT07257536 | NOT_YET_RECRUITING

3000 participants

Xinxing Eye Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-15
Completion:: 2028-11-30

Conditions

Refractive Errors
Cataract

No Results Yet

NCT07257523 | RECRUITING | PHASE2

33 participants

Carbon Ion Radiotherapy in Frail Patients With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-09-23
Completion:: 2027-07-31

Conditions

Pancreatic Neoplasm

Interventions

OTHER

No Results Yet

NCT07257510 | RECRUITING | NA

34 participants

Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-08-01
Completion:: 2028-08-01

Conditions

Mantle Cell Lymphoma (MCL)
POZ

Interventions

DRUG

No Results Yet

NCT07257471 | RECRUITING

30 participants

Application Research of Methylation Markers in Early-stage Lung Cancer Patients Treated With Co-ablation System Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-06-06
Completion:: 2028-06-30

Conditions

Lung Cancer (NSCLC)

No Results Yet

NCT07257458 | RECRUITING

30 participants

Application of Methylation Markers in Early Detection and MRD Monitoring of Lung Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-04-02
Completion:: 2028-06-30

Conditions

Lung Cancer (NSCLC)

No Results Yet

NCT07257445 | NOT_YET_RECRUITING | NA

45 participants

Modularities of Management of Severe Grades of Gynecomastia.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-31
Completion:: 2027-10-31

Conditions

Gynecomastia

Interventions

PROCEDURE

No Results Yet

NCT07257432 | ACTIVE_NOT_RECRUITING | NA

30 participants

Electronic Anesthetic Efficacy Prof. Ali Rokia Ph.D. Al-Andalus University Prof . Mouetaz Kheirallah Ph.D ArabUST

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-09-24
Completion:: 2025-09-24

Conditions

Pain Perception

Interventions

DRUG

No Results Yet

NCT07257380 | NOT_YET_RECRUITING | PHASE2

90 participants

Feasibility of Circulating Tumor DNA Based Minimal Residual Disease-Guided Adjuvant Therapy in Locally Advanced Gastric Cancer With Neoadjuvant Treatment: An Adaptive Trial (MRD-ATLAS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-30
Completion:: 2029-12-30

Conditions

Gastric / Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07257354 | COMPLETED | NA

62 participants

Reducing Examination Anxiety Through Emotional Freedom Techniques: A Randomized Controlled Trial Among Somali Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2022-09-21
Completion:: 2022-10-22

Conditions

Anxiety
Emotional Freedom Techniques

Interventions

OTHER

No Results Yet

NCT07257328 | COMPLETED | NA

32 participants

Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-05-01
Completion:: 2024-07-01

Conditions

Wound Healing
Tooth Extraction Site Healing

Interventions

PROCEDURE

No Results Yet

NCT07257315 | COMPLETED | NA

40 participants

Effectiveness of a Program to Improve Balance, Mobility, and Fall Prevention in Older Adults.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-02-02
Completion:: 2025-10-02

Conditions

Accidental Falls

Interventions

BEHAVIORAL

No Results Yet

NCT07257276 | ACTIVE_NOT_RECRUITING

294 participants

3D-CT-Based Prediction of Difficult Laryngoscopy in Infants With Pierre Robin Sequence

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-01-01
Completion:: 2024-12-31

Conditions

Pierre Robin Sequence (PRS)
Difficult Laryngoscopy
Airway Management

No Results Yet

NCT07257263 | ACTIVE_NOT_RECRUITING

6 participants

Exploring How Health Care Support Workers Respond to Distressed Behaviour in People With Dementia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-04-01
Completion:: 2025-12-31

Conditions

Dementia

No Results Yet

NCT07257224 | NOT_YET_RECRUITING

83 participants

Post-market Clinical Follow-up Study of an Isotonic Saline Solution to Manage Nasal Congestion in Case of Flu Symptoms, Colds, Allergic Rhinitis and Rhinosinusitis in Infants and Toddlers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-31
Completion:: 2026-10-31

Conditions

Nasal Congestion
Common Cold
Allergic Rhinitis
Rhinosinusitis
Flu Symptom

Interventions

DEVICE

No Results Yet

NCT07257211 | NOT_YET_RECRUITING | NA

102 participants

Partial vs Total Knee Replacement for Medial Knee Osteoarthritis: a Prospective Randomized Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2026-01-01
Completion:: 2028-01-01

Conditions

Medial Knee Osteoarthritis

Interventions

PROCEDURE

No Results Yet

NCT07257172 | RECRUITING | NA

40 participants

Sutureless Technique for Repositioning and Scleral Fixation of the Capsular Bag - Intraocular Lens Complex With Permanent Use of Iris Retractors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2021-05-28
Completion:: 2026-01-31

Conditions

Lens Subluxation

Interventions

PROCEDURE

No Results Yet

NCT07257146 | ENROLLING_BY_INVITATION

250 participants

Smart-SABI: Digital Phenotyping of Stroke Access Barriers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-10-11
Completion:: 2027-02-11

Conditions

Stroke
Practice
Healthcare Disparities
Thrombectomy
Healthcare Access

Interventions

BEHAVIORAL

No Results Yet

NCT07257107 | RECRUITING | NA

30 participants

Effect of Transcutaneous Auricular Vagus Nerve Stimulation Combined With Upper Extremity Robot-Assisted Training on Upper Extremity Motor Functions in Stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-10-01
Completion:: 2027-03-01

Conditions

Stroke Treatment
Stroke

Interventions

DEVICE
OTHER

No Results Yet

NCT07257003 | NOT_YET_RECRUITING | NA

150 participants

A Nationwide Multicenter, Single-arm, Retrospective Study of Delayed Endoscopic DTI-BR After Simple Mastectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-01
Completion:: 2026-12-31

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT07256977 | NOT_YET_RECRUITING | NA

494 participants

Minimally Invasive Radical Hysterectomy Using Endoscopic Stapler in Stage IB2 or IIA1 Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2026-01-01
Completion:: 2034-12-31

Conditions

Cervical Cancer Stage IB2
Cervical Cancer Stage IIa

Interventions

DEVICE

No Results Yet

NCT07256964 | NOT_YET_RECRUITING | PHASE2

216 participants

Toripalimab Combined With Anthracycline-free or Anthracycline-containing Chemotherapy as Neoadjuvant Chemotherapy for Early Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-11-26
Completion:: 2028-12-31

Conditions

TNBC - Triple-Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT07252271 | NOT_YET_RECRUITING | PHASE4

112 participants

Very Low Dose Prednisolone on Newly Diagnosed Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-01
Completion:: 2028-06-30

Conditions

Rhematoid Arthritis

Interventions

DRUG

No Results Yet

NCT07251556 | NOT_YET_RECRUITING | PHASE4

40 participants

GLP-1 Receptor Agonists in Non-diabetic Patients With Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-01
Completion:: 2027-01-01

Conditions

Psoriasis Arthritis

Interventions

DRUG
OTHER

No Results Yet

NCT07248488 | NOT_YET_RECRUITING | NA

1792 participants

Effect of an Intervention Combining the Use of Standardized Information and Sending an SMS Advice Message to Parents Calling the SAMU Center 15 for Uncomplicated Fever in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2026-09-07
Completion:: 2028-03-20

Conditions

Emergency Call
Fever; Pediatric Fever Management; Parental Anxiety

Interventions

OTHER

No Results Yet

NCT07247747 | NOT_YET_RECRUITING

54 participants

Turkish Validity and Reliability of VRSUQ

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-12-15
Completion:: 2026-12-01

Conditions

Healthy Volunteer

No Results Yet