Clinical Trials Updated in 2025

NCT06333314 | RECRUITING | PHASE2

120 participants

Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-07-23
Completion:: 2028-10-31

Conditions

Pancreatic Adenocarcinoma
Ampulla of Vater Carcinoma
Adrenocortical Carcinoma
Neuroendocrine Carcinoma
Soft Tissue Sarcoma
Small Bowel Adenocarcinoma
Duodenum Adenocarcinoma
Gastric Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT06299644 | NOT_YET_RECRUITING | NA

10 participants

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2026-09-30
Completion:: 2027-10-31

Conditions

Obesity
Obesity, Morbid
Metabolic Disease
Weight, Body

Interventions

DEVICE

No Results Yet

NCT06292819 | COMPLETED | NA

60 participants

Effects of Photobiomodulation on Insomnia in the Elderly: Clinical Trials of Phototherapy Devices

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-04-26
Completion:: 2025-08-31

Conditions

Photobiomodulation

Interventions

DEVICE

No Results Yet

NCT06290180 | COMPLETED | NA

92 participants

Healing Lodge First Face Training Evaluation Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-04-04
Completion:: 2025-04-30

Conditions

Addiction
Depression/Anxiety
Trauma, Psychological
Self-harm

Interventions

BEHAVIORAL

Results Available

NCT06284915 | COMPLETED | PHASE3

840 participants

Study on Immunogenicity and Safety of a Meningococcal ACYW Conjugate Vaccine in Healthy Infants and Toddlers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-03-19
Completion:: 2025-11-14

Conditions

Meningococcal Immunisation
Healthy Volunteers

Interventions

BIOLOGICAL

No Results Yet

NCT06280196 | TERMINATED | PHASE3

162 participants

A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-07-19
Completion:: 2025-07-30

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT06269744 | ENROLLING_BY_INVITATION | NA

3000 participants

Proactive Outreach With FIT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-03-13
Completion:: 2025-12-15

Conditions

Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06260215 | COMPLETED | NA

11 participants

Recovery Kinetics Following a Soccer Training in Middle-aged Males

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-02-05
Completion:: 2024-02-26

Conditions

Skeletal Muscle Damage

Interventions

OTHER

No Results Yet

NCT06249269 | RECRUITING

198 participants

Reversal of Atrial Substrate to Prevent Atrial Fibrillation Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-05-01
Completion:: 2026-12-31

Conditions

Atrial Fibrillation, Paroxysmal or Persistent

No Results Yet

NCT06245538 | COMPLETED | NA

24 participants

Exercise Intensity on Brain & Mental Health in Stress

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-02-15
Completion:: 2025-10-06

Conditions

Healthy Adults
Adults With Stress-related Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT06237842 | RECRUITING

48 participants

Wearable Technologies for Sleep in Children and Adolescents

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-11-22
Completion:: 2026-12-01

Conditions

Sleep
Pediatric Sleep Apnea

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06211504 | RECRUITING | PHASE4

130 participants

Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-07-31
Completion:: 2027-12-31

Conditions

Acquired Adult Flatfoot Deformity
Flat Foot
Flexible Flatfoot

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06189209 | RECRUITING | PHASE2

40 participants

Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-03-04
Completion:: 2026-12-31

Conditions

Triple Negative Breast Cancer (TNBC)

Interventions

DRUG

No Results Yet

NCT06187727 | COMPLETED | PHASE4

248 participants

Henagliflozin Reducing Infarct Size After Priamry PCI in Patients With ST Segment Elevation Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-07-01
Completion:: 2025-01-01

Conditions

Myocardial Infarction
Heart Failure

Interventions

DRUG

No Results Yet

NCT06181630 | WITHDRAWN | PHASE4

0 participants

A Lactation Study in Women Receiving Treatment With Ozanimod

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-11-15
Completion:: 2026-12-16

Conditions

Lactating Women
Breastfed Infants

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06129149 | COMPLETED | NA

30 participants

The R4R Advance Care Planning Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-05-14
Completion:: 2024-12-10

Conditions

Advance Care Planning

Interventions

BEHAVIORAL

Results Available

NCT06121609 | COMPLETED | NA

165 participants

ED90 of Remimazolam Anesthesia Induction in Painless Bidirectional Endoscopy in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-01-15
Completion:: 2024-04-30

Conditions

Bidirectional Endoscopy

Interventions

DRUG

Results Available

NCT06117670 | COMPLETED | PHASE3

25 participants

Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-11-01
Completion:: 2025-01-05

Conditions

Rectocele; Female
Pelvic Organ Prolapse

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06114303 | TERMINATED

14 participants

Ex-vivo Evaluation of the Effect of 2 Probiotic Solutions (Lactibiane ATB and Lactibiane Enfant) and 5 Classes of Drugs on the Intestinal Microbiota

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-03-14
Completion:: 2025-06-16

Conditions

Dysbiosis

Interventions

OTHER

No Results Yet

NCT06110975 | ACTIVE_NOT_RECRUITING | NA

72 participants

Deprescribing dRrugs for Overactive Bladder in General Practice (DROP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-12-01
Completion:: 2025-12-01

Conditions

Overactive Bladder
Deprescribing
PIMS

Interventions

OTHER

No Results Yet

NCT06103565 | COMPLETED | NA

3 participants

EHR Nudges to Improve Quality of Care in HF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2025-05-13
Completion:: 2025-07-21

Conditions

Heart Failure With Reduced Ejection Fraction

Interventions

OTHER

No Results Yet

NCT06100367 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

100 participants

11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2019-12-30
Completion:: 2025-05-25

Conditions

Primary Aldosteronism Due to Aldosterone Producing Adenoma
Primary Aldosteronism
Adrenal Tumors

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06095895 | COMPLETED

29 participants

Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-03-15
Completion:: 2024-11-15

Conditions

Pharmacokinetics
Area Under Curve
Tacrolimus
Immunosuppressive Agents
Mycophenolic Acid

Interventions

OTHER

No Results Yet

NCT06080191 | RECRUITING | PHASE1

24 participants

Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-04-28
Completion:: 2026-06-30

Conditions

B-cell Acute Lymphoblastic Leukemia

Interventions

DRUG

No Results Yet

NCT06079736 | TERMINATED | PHASE2

7 participants

A Study Of PGN-EDO51 In Participants With Duchenne Muscular Dystrophy Amenable To Exon 51-Skipping Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-01-03
Completion:: 2025-08-28

Conditions

Duchenne Muscular Dystrophy

Interventions

DRUG

No Results Yet

NCT06070610 | COMPLETED | PHASE1

14 participants

A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-11-08
Completion:: 2023-12-14

Conditions

Healthy

Interventions

DRUG

Results Available

NCT06064903 | RECRUITING | PHASE1/PHASE2

26 participants

CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2024-04-21
Completion:: 2028-09-30

Conditions

T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT06005792 | TERMINATED | PHASE1

23 participants

Multiple Ascending-Dose Study of XmAb®27564 in Patients With Psoriasis or Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2022-10-10
Completion:: 2024-03-22

Conditions

Psoriasis
Atopic Dermatitis

Interventions

BIOLOGICAL

No Results Yet

NCT06003816 | RECRUITING | NA

3140 participants

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-10-18
Completion:: 2026-11-30

Conditions

Cholera
Diarrhea

Interventions

BEHAVIORAL

No Results Yet

NCT05990244 | RECRUITING | NA

100 participants

Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2017-01-01
Completion:: 2026-07-01

Conditions

Glioma

Interventions

DIAGNOSTIC_TEST
PROCEDURE

No Results Yet

NCT05954637 | COMPLETED

60 participants

Correlation of Structure and Function in Glaucoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-07-01
Completion:: 2024-12-31

Conditions

Glaucoma

Interventions

DEVICE

No Results Yet

NCT05918055 | TERMINATED | PHASE1/PHASE2

3 participants

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-11-14
Completion:: 2025-03-10

Conditions

Myelodysplastic Syndromes

Interventions

DRUG
PROCEDURE
DIAGNOSTIC_TEST

Results Available

NCT05911841 | TERMINATED | PHASE2

234 participants

A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-06-21
Completion:: 2024-10-10

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT05892341 | COMPLETED | NA

203 participants

AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2022-12-05
Completion:: 2024-02-14

Conditions

Venous Leg Ulcer
Diabetic Foot

Interventions

DEVICE

Results Available

NCT05874726 | ACTIVE_NOT_RECRUITING

500 participants

Biological Sample Repository for Gastrointestinal Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-07-19
Completion:: 2028-07-31

Conditions

Obesity
Obesity, Morbid
Obesity, Primary
Gastro-Intestinal Disorder
Overweight and Obesity
Overweight
Overweight or Obesity
Diabetes Type 2
Diabetes Mellitus
Diabetes Mellitus, Type 2
Hypertension
Hyperlipidemias
Sleep Apnea
GERD
Gastroesophageal Reflux
Musculoskeletal Pain Disorder
Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05851976 | RECRUITING | PHASE4

120 participants

Duloxetine for LBP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-10-04
Completion:: 2027-05-31

Conditions

Back Pain, Low

Interventions

DRUG

No Results Yet

NCT05846087 | COMPLETED | NA

106 participants

Mobile App-delivered Sleep Therapy (SleepFix) for Individuals With Chronic Low Back Pain and Insomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-09-13
Completion:: 2025-10-30

Conditions

Chronic Low-back Pain
Insomnia

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05816070 | COMPLETED | PHASE2

129 participants

Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Bacterial Conjunctivitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-01-05
Completion:: 2023-11-13

Conditions

Acute Bacterial Conjunctivitis

Interventions

DRUG

Results Available

NCT05801510 | COMPLETED | NA

36 participants

Cognitive Muscular Therapy for People Awaiting Knee Joint Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-03-01
Completion:: 2025-04-30

Conditions

Knee Osteoarthritis

Interventions

BEHAVIORAL

No Results Yet

NCT05786716 | RECRUITING | PHASE2/PHASE3

30 participants

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-02
Start Date:: 2023-03-07
Completion:: 2029-10-31

Conditions

Haematological Malignancy
Colorectal Neoplasms
Urinary Bladder Neoplasm
Gallbladder Neoplasms
Salivary Gland Neoplasm
Lung Neoplasm
Pancreatic Neoplasm
Ovarian Neoplasms
Prostatic Neoplasm
Skin Neoplasm
Solid Tumour

Interventions

DRUG

No Results Yet