Clinical Trials Updated in 2025

NCT06642571 | COMPLETED | PHASE1

46 participants

A Research Study to Compare How Much of the Medicine NNC0519-0130 is in the Blood of People With Overweight or Obesity Who Receive 2 Preparations of the Medicine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-10-15
Completion:: 2025-05-17

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06632717 | RECRUITING | PHASE2

24 participants

Hepatic Arterial Infusion Chemotherapy With Lipiodol Embolization in Advanced Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-01
Completion:: 2026-01-31

Conditions

Hepatocellular Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06631274 | COMPLETED | NA

48 participants

Intervention for Victimized Youth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-10-21
Completion:: 2025-03-10

Conditions

Victimization

Interventions

BEHAVIORAL

Results Available

NCT06628349 | RECRUITING | NA

100 participants

Prandial Metabolic Phenotyping in Sarcopenic Older Adults Comparing Plant Based and Whey Based Protein

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-02-01
Completion:: 2026-12-31

Conditions

Protein Metabolism

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06621641 | COMPLETED | NA

150 participants

Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-10-01
Completion:: 2025-05-30

Conditions

Bronchiolitis
Respiratory Failure (Pediatric Patients)
High Flow Nasal Cannula

Interventions

BEHAVIORAL

No Results Yet

NCT06621407 | RECRUITING | NA

354 participants

A National Study Examining the Most Effective Drainage Method After Burr Hole Evacuation of Chronic Subdural Hematoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2025-09-01
Completion:: 2027-08-31

Conditions

Chronic Subdural Hematoma
Surgical Procedures, Operative
Recurrence
Mortality
Drainage
Drainage/Methods
Drainage Procedure

Interventions

PROCEDURE

No Results Yet

NCT06615726 | ACTIVE_NOT_RECRUITING | PHASE3

1300 participants

Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-10-10
Completion:: 2026-11-19

Conditions

Ischemic Stroke
Transient Ischemic Attack

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06608030 | COMPLETED | NA

142 participants

Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-23
Completion:: 2025-04-07

Conditions

Depression, Anxiety
Cardiac Surgery
S-ketamine

Interventions

DRUG

No Results Yet

NCT06603493 | COMPLETED

132 participants

Headaches: Effects on Sleep, Sensitization, and Psychological Factors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-19
Completion:: 2024-11-19

Conditions

Headache Disorder

Interventions

OTHER

No Results Yet

NCT06598774 | COMPLETED

40 participants

Cervical Parameters and Body Awareness in Relation to Smartphone Addiction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-18
Completion:: 2024-11-18

Conditions

Smartphone Addiction

Interventions

OTHER

No Results Yet

NCT06590441 | COMPLETED

53 participants

Investigation of Wearing Compliance of Spectacles for Myopia Control

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-30
Completion:: 2025-01-18

Conditions

Myopia

Interventions

DEVICE

Results Available

NCT06589934 | COMPLETED | NA

30 participants

Clinical Study of CT 5400 RT for Precise Image Validation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2025-01-25
Completion:: 2025-01-25

Conditions

Precise Image (AI Reconstruction Feature of CT 5400 RT System)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06586411 | COMPLETED

40 participants

Comparison of Oxygenation Index and Oxygen Stretch Index

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-11-05
Completion:: 2025-08-30

Conditions

Pediatric Acute Respiratory Distress Syndrome

No Results Yet

NCT06582901 | RECRUITING | NA

54 participants

Interventions for Clinical High Risk Youth in Tunisia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2023-09-01
Completion:: 2025-08-31

Conditions

Clinical High Risk for Psychosis (CHR)

Interventions

BEHAVIORAL

No Results Yet

NCT06581302 | RECRUITING | NA

50 participants

Magnetic Seizure Therapy for Psychotic Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-01
Completion:: 2025-12-30

Conditions

Psychotic Disorders

Interventions

DEVICE
DRUG

No Results Yet

NCT06559462 | COMPLETED | NA

50 participants

Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-19
Completion:: 2025-04-25

Conditions

DPYD Gene Mutation
Gastrointestinal Cancer
Health Care Seeking Behavior

Interventions

OTHER

No Results Yet

NCT06559397 | COMPLETED

60 participants

Proprioceptive Puzzle: Effects on Quantitative Sensory Tests and Body Awareness

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-09-01
Completion:: 2025-01-01

Conditions

Cervical Proprioceptive Error in Healthy Young Individuals

Interventions

OTHER

No Results Yet

NCT06558318 | COMPLETED

60 participants

TMJ Dysfunction: Effects on Proprioception, Pain, and Body Awareness

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-08-19
Completion:: 2024-12-19

Conditions

Temporomandibular Joint Disorders
Temporomandibular Disorder

Interventions

OTHER

No Results Yet

NCT06558136 | COMPLETED

60 participants

Evaluation of Salivary Biomarker Levels in Individuals With Different Periodontal Conditions

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-08-01
Completion:: 2025-10-15

Conditions

Periodontitis
Gingivitis
Periodontal Health

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06533566 | COMPLETED | NA

37 participants

Erector Spinae Plane Block Versus Local Wound Infiltration After Modified Radical Mastectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-08-10
Completion:: 2025-07-01

Conditions

Post Operative Pain
Erector Spinae Plane Block
Local Infiltration

Interventions

PROCEDURE

No Results Yet

NCT06501638 | COMPLETED | PHASE2

256 participants

Efficacy and Safety of memanTine in the Treatment Of Frequently symPtomatic Atrial Premature Beats

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-08-29
Completion:: 2025-03-21

Conditions

Atrial Premature Beats, Contractions, or Systoles

Interventions

DRUG

No Results Yet

NCT06495164 | ACTIVE_NOT_RECRUITING

1 participants

A Real-life Study to Understand the Use and Effects of Palbociclib in US Patients With Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-06-24
Completion:: 2026-12-30

Conditions

Breast Cancer
Malignant Neoplasm of Breast

Interventions

DRUG

No Results Yet

NCT06493240 | COMPLETED | PHASE2

30 participants

Neoadjuvant Long-course Chemoradiotherapy Followed by Immunotherapy for Locally Advanced Mid-low Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2023-01-01
Completion:: 2025-04-01

Conditions

Locally Advanced Rectal Cancer

Interventions

RADIATION
DRUG
PROCEDURE

No Results Yet

NCT06489951 | COMPLETED | NA

180 participants

Efficacy and Mechanism of High-Dose Vitamin D Supplementation in Pediatric OAB-Dry: A Randomized Clinical Trial Integrating Urinary Myelin Basic Protein as a Theranostic Biomarker

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-12-28
Completion:: 2025-06-30

Conditions

Overactive Bladder
Pediatric Disorder

Interventions

DRUG
DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT06489340 | WITHDRAWN | PHASE2

0 participants

P2a Open Label Study to Evaluate 2-HPβCD in Subjects With Diabetic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2025-06-11
Completion:: 2026-08-11

Conditions

Diabetic Kidney Disease

Interventions

DRUG

No Results Yet

NCT06484790 | RECRUITING | PHASE1

9 participants

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-04-08
Completion:: 2026-04-07

Conditions

Tumor, Solid

Interventions

DRUG

No Results Yet

NCT06478251 | RECRUITING | PHASE1

9 participants

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-02-01
Completion:: 2026-06-30

Conditions

Tumor, Solid

Interventions

DRUG

No Results Yet

NCT06472921 | COMPLETED | PHASE2

204 participants

Efficacy and Safety of Early Initiation of Butylphthalide Treatment in Patients With Acute Ischemic Stroke.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-07-29
Completion:: 2025-11-01

Conditions

Acute Ischemic Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT06470542 | COMPLETED | PHASE4

60 participants

Two-level ESPB in Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-11-07
Completion:: 2025-08-05

Conditions

Knee Osteoarthritis
Knee Pain Chronic
Knee Arthritis

Interventions

DRUG

No Results Yet

NCT06452238 | COMPLETED | NA

40 participants

External Oblique Intercostal Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-06-12
Completion:: 2025-10-22

Conditions

External Oblique Intercostal Plane Block
Transversus Abdominis Plane Block
Postoperative Analgesia
Nephrectomy

Interventions

OTHER

No Results Yet

NCT06452225 | COMPLETED | NA

40 participants

Transversus Abdominis Plane Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia in Pediatrics Undergoing Open Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-06-12
Completion:: 2025-10-20

Conditions

Transversus Abdominis Plane Block
External Oblique Intercostal Plane Block
Postoperative Analgesia
Pediatrics
Open Nephrectomy

Interventions

OTHER

No Results Yet

NCT06434038 | WITHDRAWN | PHASE1

0 participants

Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2025-08-30
Completion:: 2026-02-28

Conditions

Healthy

Interventions

OTHER
DRUG

No Results Yet

NCT06409078 | COMPLETED | NA

42 participants

Repetitive Transcranial Magnetic Stimulation Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-04-01
Completion:: 2025-11-19

Conditions

Irritable Bowel Syndrome
Repetitive Transcranial Magnetic Stimulation
Chronic Visceral Pain
Functional Magnetic Resonance Imaging

Interventions

DEVICE

No Results Yet

NCT06400160 | NOT_YET_RECRUITING | PHASE1/PHASE2

12 participants

Clinical Trial of TB511 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2026-03-31
Completion:: 2027-03-31

Conditions

NSCLC
Prostate Cancer
Colorectal Cancer
Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT06389292 | RECRUITING | PHASE3

486 participants

A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacitidine in the Treatment of Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-06-11
Completion:: 2028-05-25

Conditions

Acute Myeloid Leukemia

Interventions

DRUG
OTHER

No Results Yet

NCT06362044 | COMPLETED

89 participants

A Study to Assess Frequency of Undetectable Minimal Residual Disease (uMRD) in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets ± Intravenously (IV) Infused Rituximab in Routine Clinical Practice in Japan

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-25
Start Date:: 2023-06-07
Completion:: 2024-12-31

Conditions

Chronic Lymphocytic Leukemia

No Results Yet

NCT06352593 | COMPLETED | NA

90 participants

Intraoperative Dexmedetomidine Infusion in Endovascular Intervention for Aneurysmal Subarachnoid Hemorrhage

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-04-06
Completion:: 2025-10-22

Conditions

Dexmedetomidine
Infusion
Endovascular
Aneurysmal Subarachnoid Hemorrhage

Interventions

DRUG
OTHER

No Results Yet

NCT06341179 | RECRUITING | NA

142 participants

Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2024-08-13
Completion:: 2027-12-31

Conditions

Sleep Duration
Child Obesity
Child Development
Child Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06331871 | COMPLETED | NA

70 participants

Effectiveness of Ultrasound-Guided Nerve Stimulation for Patients With Post-surgical Shoulder Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2023-11-01
Completion:: 2025-03-25

Conditions

Ultrasound-Guided Percutaneous Electrical Nerve Stimulation

Interventions

PROCEDURE

No Results Yet

NCT06311851 | RECRUITING | PHASE1/PHASE2

40 participants

Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-25
Start Date:: 2025-06-01
Completion:: 2026-03-30

Conditions

Cancer
Metastatic Cancer
Liver Metastases

Interventions

DRUG

No Results Yet