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Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery

NCT06608030 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 142

Last updated 2025-11-25

No results posted yet for this study

Summary

A multicenter, randomized controlled, blinded prospective study to investigate the effects of esketamine on perioperative anxiety and depression in patients undergoing cardiac valve surgery.

Conditions

  • Depression, Anxiety
  • Cardiac Surgery
  • S-ketamine

Interventions

DRUG

Esketamine

A single dose of 0.3mg / kg esketamine during induction of anesthesia.

DRUG

normal saline

Receiving the same volume of normal saline during induction of anesthesia.

Sponsors & Collaborators

  • Beijing Tiantan Hospital

    collaborator OTHER

  • The Sixth Medical Center of Chinese PLA General Hospital

    collaborator UNKNOWN

  • Chinese PLA General Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-23
Primary Completion
2025-04-07
Completion
2025-04-30

Countries

  • China

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06608030 on ClinicalTrials.gov