Clinical Trials Updated in 2025

NCT04713657 | RECRUITING | PHASE1

40 participants

Beta-blocker Administration for Cardiomyocyte Division

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-12-16
Completion:: 2030-12-31

Conditions

Tetralogy of Fallot
Double Outlet Right Ventricle

Interventions

OTHER
PROCEDURE
DRUG

No Results Yet

NCT04687033 | COMPLETED | NA

34 participants

The Effect of The Ten-Session Dual-tDCS On Lower-Limb Performance in Sub- Acute and Chronic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-01-01
Completion:: 2023-11-30

Conditions

Stroke, Ischemic

Interventions

DEVICE

No Results Yet

NCT04681573 | RECRUITING | NA

1045 participants

Comparison of Two sTRAtegies For the Non-Invasive Diagnosis of advanCed Liver Fibrosis in NAFLD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-04-07
Completion:: 2028-10-07

Conditions

NAFLD

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04652609 | RECRUITING | NA

25 participants

Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-01-01
Completion:: 2025-01-01

Conditions

Breast Neoplasm

Interventions

OTHER

No Results Yet

NCT04624399 | RECRUITING | PHASE2

58 participants

Neoadjuvant Immune Checkpoint Inhibitor Treatment in Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-06-17
Completion:: 2026-05-30

Conditions

Urogenital Cancer

Interventions

DRUG

No Results Yet

NCT04583124 | COMPLETED | NA

42 participants

Adjusting the Dose of Therapeutic Exercise to Prevent Neurotoxicity Due to Anticancer Treatment (ATENTO)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-09-30
Completion:: 2024-12-31

Conditions

Breast Neoplasm

Interventions

OTHER

No Results Yet

NCT04581954 | COMPLETED | PHASE1/PHASE2

185 participants

Inflammatory Signal Inhibitors for COVID-19 (MATIS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-10-02
Completion:: 2022-11-30

Conditions

Coronavirus
Covid19
Pneumonia

Interventions

DRUG
OTHER

No Results Yet

NCT04557293 | RECRUITING | NA

64 participants

Effort-based Decision-making and CPAP Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-03-10
Completion:: 2026-04-30

Conditions

Obstructive Sleep Apnea
Adherence

Interventions

DEVICE

No Results Yet

NCT04549428 | TERMINATED | PHASE2

12 participants

Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-10-01
Completion:: 2023-01-23

Conditions

NSCLC Stage IV

Interventions

DRUG

No Results Yet

NCT04543799 | RECRUITING

60 participants

Evaluation of Sleep Quality in Prostate Cancer Patients Undergoing Treatment With Hormonal Therapeutic Approaches and in Patients With Full-resected Early Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-09-24
Completion:: 2026-12-31

Conditions

Prostate Cancer
Breast Cancer

Interventions

DEVICE

No Results Yet

NCT04534153 | COMPLETED | EARLY_PHASE1

12 participants

Excipient Effect on Drug Absorption in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-01-31
Completion:: 2025-06-18

Conditions

The Impact of Excipients on Drug Absorption

Interventions

DRUG

No Results Yet

NCT04533672 | COMPLETED | NA

186 participants

Multiparametric Magnetic Resonance Imaging (MRI) to Improve Bladder Cancer Staging and Treatment Decision-making

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-02-01
Completion:: 2025-10-01

Conditions

Bladder Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04510766 | RECRUITING

40 participants

Tumor Molecular Profiling in Early Phase Clinical Trials

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-10-01
Completion:: 2026-12-31

Conditions

Advanced Solid Tumor
Lymphoma

No Results Yet

NCT04496115 | NOT_YET_RECRUITING | NA

60 participants

Mindfulness in High Risk Pregnancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2026-09-01
Completion:: 2026-12-31

Conditions

Stress
Anxiety
Depression
Mindfulness

Interventions

BEHAVIORAL

No Results Yet

NCT04440761 | RECRUITING

3000 participants

Barts-MINOCA Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-07-01
Completion:: 2026-09-16

Conditions

Myocardial Infarction
Gender
Coronary Microvascular Disease

Interventions

OTHER

No Results Yet

NCT04428554 | RECRUITING | PHASE2

130 participants

Consolidative Radiotherapy for Metastatic Urothelial Bladder Cancer Patients Without Progression and With no More Than Three Residual Metastatic Lesions Following First Line Systemic Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-06-30
Completion:: 2031-07-31

Conditions

Urothelial Bladder Cancer

Interventions

RADIATION

No Results Yet

NCT04425018 | ACTIVE_NOT_RECRUITING | PHASE2

174 participants

MARGetuximab Or Trastuzumab (MARGOT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-07-13
Completion:: 2024-10-24

Conditions

Breast Cancer
Stage II Breast Cancer
Stage III Breast Cancer
HER2-positive Breast Cancer

Interventions

DRUG

Results Available

NCT04404114 | RECRUITING

800 participants

Shear Wave Elastography in Differentiating Acute or Chronic Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-02-01
Completion:: 2026-12-31

Conditions

Elastography
Chronic Kidney Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04381143 | RECRUITING | PHASE4

9000 participants

ASPIrin in Reducing Events in Dialysis ( ASPIRED )

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-07-30
Completion:: 2026-09-30

Conditions

CKD (Chronic Kidney Disease) Stage 5D

Interventions

DRUG

No Results Yet

NCT04351958 | ENROLLING_BY_INVITATION | NA

20 participants

An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2025-09-12
Completion:: 2026-02-28

Conditions

Alcohol Prevention
Harm Reduction

Interventions

BEHAVIORAL

No Results Yet

NCT04337021 | COMPLETED | NA

199 participants

Caregiver Self-Management of Stress

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-12-28
Completion:: 2024-03-31

Conditions

Caregiver Distress
Job Stress

Interventions

BEHAVIORAL

Results Available

NCT04288128 | COMPLETED

40 participants

Integrated Functional Evaluation of the Cerebellum

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-05-28
Completion:: 2022-05-20

Conditions

Spinocerebellar Ataxia Type 2
Spinocerebellar Ataxia Type 7

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04270838 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

174 participants

A Phase Ib/II Study of the Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-02-17
Completion:: 2028-09-30

Conditions

Rabies

Interventions

BIOLOGICAL

No Results Yet

NCT04232293 | COMPLETED | NA

722 participants

Screening of Liver Fibrosis Using Blood Tests in Patients With Type 2 Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-06-25
Completion:: 2025-06-27

Conditions

Diabetes Mellitus, Type 2
NAFLD
NASH

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04190862 | RECRUITING | PHASE1

39 participants

E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-01-22
Completion:: 2026-09-30

Conditions

Anal Fistula

Interventions

DRUG

No Results Yet

NCT04185246 | COMPLETED | PHASE1/PHASE2

36 participants

A Dose Ascending Study to Evaluate the Safety of NH002 as a Contrast Agent in Cardiac Echocardiography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-11-04
Completion:: 2020-07-01

Conditions

Cardiac Disease

Interventions

DRUG
DIAGNOSTIC_TEST

Results Available

NCT04156061 | ACTIVE_NOT_RECRUITING | NA

400 participants

Effect of the SCOT-HEART 2 Trial on Lifestyle.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-09-28
Completion:: 2024-01-12

Conditions

Coronary Artery Disease
Primary Prevention

Interventions

OTHER

No Results Yet

NCT04129021 | RECRUITING | NA

1200 participants

High Resolution, High-speed Multimodal Ophthalmic Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-07-03
Completion:: 2027-07-31

Conditions

Retinitis Pigmentosa
Maculopathy, Age Related
Macular Dystrophy
Macular Edema
Retinal Detachment
Retinal Degeneration
Glaucoma
Vascular Inflammation
Hypertension
Stroke
Diabetes
Corneal Dystrophy
Keratoconus
Dry Eye
Trauma

Interventions

DEVICE

No Results Yet

NCT04124302 | COMPLETED | PHASE4

76 participants

The Impact of Two Different Insulin Dose Calculation on Postprandial Glycemia After Mixed Meal.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-10-01
Completion:: 2024-03-27

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT04070443 | ACTIVE_NOT_RECRUITING | PHASE2

170 participants

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-11-13
Completion:: 2029-06-01

Conditions

Philadelphia Chromosome Positive CML
BCR-ABL Positive Chronic Myelogenous Leukemia

Interventions

DRUG

No Results Yet

NCT04042701 | ACTIVE_NOT_RECRUITING | PHASE1

115 participants

DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-02-10
Completion:: 2025-07-21

Conditions

Breast Cancer
Non-small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT04039802 | COMPLETED

70 participants

Single-stage Surgery Using the BHX Implant

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-09-01
Completion:: 2023-07-24

Conditions

Hearing Impairment, Conductive
Hearing Impaired Children

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04038216 | TERMINATED

70 participants

Single-stage Surgery Using the BI300 Implant

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-09-01
Completion:: 2025-03-25

Conditions

Hearing Impaired Children
Hearing Impairment, Conductive

Interventions

PROCEDURE
OTHER

No Results Yet

NCT03998462 | COMPLETED | NA

107 participants

Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-01-01
Completion:: 2024-11-01

Conditions

Parkinson's Disease

Interventions

BEHAVIORAL

Results Available

NCT03984578 | COMPLETED | PHASE2

33 participants

Window of Opportunity Study in Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-06-12
Completion:: 2025-02-28

Conditions

Colorectal Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03977194 | ACTIVE_NOT_RECRUITING | PHASE3

510 participants

Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-07-23
Completion:: 2024-08-31

Conditions

Non Small Cell Lung Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT03954171 | RECRUITING | NA

600 participants

Platino-resistance in Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-03-06
Completion:: 2033-03-31

Conditions

Epithelial Ovarian Cancer

Interventions

OTHER

No Results Yet

NCT03954054 | COMPLETED

110 participants

Therapeutic Education for Harm Reduction in People With Alcohol Use Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-10-28
Completion:: 2021-07-31

Conditions

Alcohol Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT03941587 | COMPLETED | NA

60 participants

Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-02-01
Completion:: 2024-06-06

Conditions

Polypoidal Choroidal Vasculopathy

Interventions

DRUG

No Results Yet

NCT03929731 | COMPLETED

72 participants

Long-term Outcomes, Recurrence Rates, and Treatment Needs in Polypoidal Choroidal Vasculopathy (PCV)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-07-05
Completion:: 2024-05-09

Conditions

Polypoidal Choroidal Vasculopathy

Interventions

DIAGNOSTIC_TEST

No Results Yet