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Barts-MINOCA Registry

NCT04440761 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000

Last updated 2025-11-18

No results posted yet for this study

Summary

The last 15 years the introduction of primary angioplasty has radically improved outcomes for acute myocardial infarction (AMI). However, the system wide availability of prompt investigation has revealed an important group of patients where progress has stalled, the diagnosis is unclear and therapeutic approaches are uncertain. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is found in 1 - 13% of all patients with a clinical diagnosis of AMI.

These patients present a therapeutic predicament since coronary revascularization is not appropriate. Guidelines do not exist for their management - yet the condition is not benign - the 12-month prognosis, although better than obstructive coronary artery disease patients is still guarded with recent data suggesting many questions remain unanswered.

Conditions

Interventions

OTHER

Observation only

Observation only

Sponsors & Collaborators

  • Queen Mary University of London

    lead OTHER

Principal Investigators

  • Daniel Jones, MBBS, PhD · Queen Mary University of London

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2026-09-16
Completion
2026-09-16

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04440761 on ClinicalTrials.gov