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Integrated Functional Evaluation of the Cerebellum

NCT04288128 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2025-11-18

No results posted yet for this study

Summary

One of the main objectives of this project is to validate potential biological, clinical and/or imaging biomarkers in SCA patients through a multimodal assessment, for future ASOs trials.

Conditions

  • Spinocerebellar Ataxia Type 2
  • Spinocerebellar Ataxia Type 7

Interventions

PROCEDURE

Lumbar puncture

Each participant will undergo lumbar puncture at first visit (M0) and last visit (M12)

OTHER

Magnetic Resonance Imaging (MRI)

Each participant will undergo scanning at 3 visits (M0, M6 and M12)

Sponsors & Collaborators

  • Biogen

    collaborator INDUSTRY

  • Ionis Pharmaceuticals, Inc.

    collaborator INDUSTRY

  • Institut National de la Santé Et de la Recherche Médicale, France

    lead OTHER_GOV

Principal Investigators

  • Alexandra DURR · Institut du Cerveau - Paris Brain Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-05-28
Primary Completion
2022-05-20
Completion
2022-06-01

Countries

  • France

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04288128 on ClinicalTrials.gov