Clinical Trials Updated in 2025

NCT05527704 | ACTIVE_NOT_RECRUITING | PHASE3

608 participants

the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-12-31
Completion:: 2025-11-30

Conditions

TTN
Respiratory Failure
PPHN

Interventions

DRUG

No Results Yet

NCT05524103 | COMPLETED | PHASE1

24 participants

Study to Evaluate the Safety and Pharmacokinetics of ALMB-0166 in Patients With Acute Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-04-15
Completion:: 2025-02-08

Conditions

Acute Spinal Cord Injury

Interventions

DRUG

No Results Yet

NCT05522556 | AVAILABLE

Pre-approval Single-patient Expanded Access for Ritlecitinib (PF-06651600)

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-18

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT05509413 | COMPLETED | NA

242 participants

DEFLAGYN® Vaginal Gel and Spontaneous Remission and Regression of Unclear Cervical Smears and HPV High-risk Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-11-08
Completion:: 2025-05-23

Conditions

Cervix Dysplasia
HPV Infection

Interventions

DEVICE

No Results Yet

NCT05500001 | RECRUITING | NA

113 participants

Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-09-01
Completion:: 2026-09-01

Conditions

Psychotic Disorders
Family Members
Anosognosia
Paranoia

Interventions

BEHAVIORAL

No Results Yet

NCT05456126 | COMPLETED

122 participants

Artificial Intelligence for Infant Motor Screening: Development and Validation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-08-01
Completion:: 2025-05-17

Conditions

Motor Disorders

No Results Yet

NCT05438459 | RECRUITING | PHASE1/PHASE2

130 participants

GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-06-08
Completion:: 2028-12-31

Conditions

Gastric Cancer
Pancreatic Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05431595 | RECRUITING | PHASE2/PHASE3

42 participants

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-07-19
Completion:: 2027-02-02

Conditions

Delirium
Epileptics
Neuroleptics

Interventions

DRUG

No Results Yet

NCT05429138 | RECRUITING

80 participants

Ovarian Reserve and Semen Parameters Evolution During Adjuvant Therapy in Melanoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-12-07
Completion:: 2026-12-31

Conditions

Melanoma

Interventions

OTHER

No Results Yet

NCT05417386 | TERMINATED | PHASE1

4 participants

FOLFIRINOX + NIS793 in Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-08-09
Completion:: 2023-07-10

Conditions

Pancreas Cancer
Metastatic Pancreatic Cancer
Metastatic Pancreatic Adenocarcinoma

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT05399485 | COMPLETED | PHASE3

496 participants

Efficacy and Safety Study of Rimegepant for Migraine Prevention in Japanese Subjects (Japan Only)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-08-09
Completion:: 2024-01-18

Conditions

Migraine

Interventions

DRUG

Results Available

NCT05396001 | COMPLETED | NA

410 participants

LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-08-15
Completion:: 2025-10-31

Conditions

Hypertension
Blood Pressure

Interventions

BEHAVIORAL

No Results Yet

NCT05299086 | COMPLETED | PHASE3

68 participants

As Needed Versus Regular Intranasal Corticosteroid in Children With Perennial Allergic Rhinitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-04-04
Completion:: 2025-03-30

Conditions

Perennial Allergic Rhinitis
Child, Only

Interventions

DRUG

No Results Yet

NCT05278065 | COMPLETED | NA

17 participants

E-cigarettes for Harm Reduction in Adults With Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-05-01
Completion:: 2024-09-12

Conditions

Smoking
Asthma
Electronic Cigarette Use
Cigarette Smoking

Interventions

OTHER

Results Available

NCT05260424 | COMPLETED

397 participants

Predictors for Nasal Intermittent Positive Pressure Ventilation Failure for Premature Infants With Respiratory Distress Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-12-01
Completion:: 2024-02-01

Conditions

Premature
Respiratory Distress Syndrome, Newborn

Interventions

OTHER

No Results Yet

NCT05236881 | COMPLETED | NA

36 participants

Development of an mHealth Tool (ANíMATE) to Assess Self-management, Self-care and Adherence in People With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-04-20
Completion:: 2024-11-13

Conditions

Obesity

Interventions

DEVICE

No Results Yet

NCT05197920 | RECRUITING

800 participants

Diabetes RElated to Acute Pancreatitis and Its Mechanisms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-01-14
Completion:: 2030-01-31

Conditions

Acute Pancreatitis

No Results Yet

NCT05179278 | COMPLETED | NA

194 participants

Impact of a PROgram of Cardiovascular Nurse interventionS in a VALVular haEmodynamic Unit (PROCESS-VALVE) on Quality Indicators: a Quasi-experimental Ambispective Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-02-25
Completion:: 2024-06-01

Conditions

Valvular Heart Disease

Interventions

OTHER

No Results Yet

NCT05177965 | COMPLETED

72 participants

The Metabolic and Circadian Effects of Shift Work

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-02-01
Completion:: 2024-08-30

Conditions

Shift Work Schedule

Interventions

OTHER

No Results Yet

NCT05064501 | WITHDRAWN

0 participants

Impact of COVID19 on Asthma Patients in Spain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-02-01
Completion:: 2023-02-01

Conditions

Asthma
Covid19

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05058066 | COMPLETED | NA

51 participants

10-year Follow-up of a Wide Diameter Bone Anchored Hearing Implant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2019-06-24
Completion:: 2020-09-21

Conditions

Hearing Loss

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT05056922 | COMPLETED | NA

80 participants

Telehealth Rapid Intervention for Externalizing Behaviors in ASD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-02-11
Completion:: 2025-09-22

Conditions

Autism Spectrum Disorder
Disruptive Behavior
Externalizing Behavior
Parent-Child Interaction Therapy
Telehealth

Interventions

BEHAVIORAL

No Results Yet

NCT05004298 | COMPLETED | NA

60 participants

Evaluation of an Animal Assisted Therapy Program in People With Mental Illness, and Promotion of Positive Mental Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-10-01
Completion:: 2024-06-15

Conditions

Mental Disorders, Severe

Interventions

OTHER

No Results Yet

NCT04999384 | RECRUITING | PHASE1

31 participants

First in Human, Dose Escalation Study of AN4005

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-09-27
Completion:: 2026-11-30

Conditions

Advanced Solid Tumor
Advanced Lymphoma

Interventions

DRUG

No Results Yet

NCT04982848 | NOT_YET_RECRUITING

600 participants

Korea Post Marketing Surveillance (PMS) Study of Talzenna®

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2027-06-01
Completion:: 2028-11-01

Conditions

Breast Neoplasms

Interventions

DRUG

No Results Yet

NCT04980716 | RECRUITING | PHASE3

524 participants

Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-06-01
Completion:: 2026-01-31

Conditions

Non-small Cell Lung Cancer
Cardiovascular Complication

Interventions

DRUG

No Results Yet

NCT04943341 | COMPLETED | NA

30 participants

Evaluation of the Triamcinolone -Acetonide Therapy for the Treatment of the Medial Plica Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-10-28
Completion:: 2024-09-16

Conditions

Medial Plica Syndrome

Interventions

PROCEDURE

No Results Yet

NCT04902352 | ACTIVE_NOT_RECRUITING | NA

102 participants

The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-04-06
Completion:: 2026-10-06

Conditions

Pancreatic Adenocarcinoma

Interventions

PROCEDURE

No Results Yet

NCT04895579 | COMPLETED | PHASE1

11 participants

Lung Cancer With Copanlisib and Durvalumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-05-12
Completion:: 2025-11-12

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04879485 | COMPLETED | NA

120 participants

Prehospital Transfusion Strategy in Bleeding Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-05-03
Completion:: 2024-12-31

Conditions

Hemorrhage
Blood Component Transfusion

Interventions

BIOLOGICAL

No Results Yet

NCT04873583 | RECRUITING | PHASE3

70 participants

High Dose Steroids in Children With Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-11-16
Completion:: 2026-07-31

Conditions

Paediatric Stroke

Interventions

DRUG

No Results Yet

NCT04868682 | COMPLETED | NA

106 participants

Addressing Insufficient PAP Use in Older Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-01-10
Completion:: 2025-08-30

Conditions

Sleep Apnea

Interventions

BEHAVIORAL

Results Available

NCT04867642 | COMPLETED | PHASE1

100 participants

A Study to Test the Safety, Tolerability, and Blood Levels of UCB0022 in Healthy Participants and Participants With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-04-29
Completion:: 2023-02-27

Conditions

Healthy Study Participants
Parkinson's Disease

Interventions

DRUG
OTHER

No Results Yet

NCT04837417 | COMPLETED

10 participants

Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the "Learned Non-use" Paradigm and the Interhemispheric Inhibition

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-07-14
Completion:: 2024-12-31

Conditions

Anterior Cruciate Ligament Injuries

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04828486 | COMPLETED | PHASE2

14 participants

Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-08-17
Completion:: 2024-09-18

Conditions

Advanced Hepatocellular Carcinoma
BCLC Stage A Hepatocellular Carcinoma
BCLC Stage B Hepatocellular Carcinoma
BCLC Stage C Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma

Interventions

DRUG
BIOLOGICAL
OTHER

Results Available

NCT04799119 | ACTIVE_NOT_RECRUITING | NA

100 participants

Multi-site Animal Assisted Intervention for Children With DD and Their Family Dog

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-02-04
Completion:: 2026-08-01

Conditions

Physical Activity
Social Wellbeing

Interventions

BEHAVIORAL

No Results Yet

NCT04790266 | COMPLETED

150 participants

Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Breast Cancer Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-09-15
Completion:: 2023-12-14

Conditions

Cardiotoxicity

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04781309 | COMPLETED | EARLY_PHASE1

12 participants

NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal Leukoencephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-05-05
Completion:: 2025-11-07

Conditions

Progressive Multifocal Leukoencephalopathy

Interventions

DRUG

No Results Yet

NCT04745637 | AVAILABLE

Managed Access Programs for INC424, Ruxolitinib

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-18

Conditions

Primary Myelofibrosis (PMF)
Post Polycythemia Myelofibrosis (PPV MF)
Thrombocythemia Myelofibrosis (PET-MF)
Severe/Very Severe COVID-19 Illness
Polycythemia Vera (PV)
Steroid Refractory Acute Graft Versus Host Disease (SR aGVHD)
Steroid Refractory Chronic Graft Versus Host Disease (SR cGVHD)

Interventions

DRUG

No Results Yet

NCT04744220 | COMPLETED | NA

60 participants

Evaluation of the Effect of Yoga Training on Functional Capacity and Quality of Life in Patients With Bronchiectasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2020-11-25
Completion:: 2022-11-20

Conditions

Bronchiectasis Adult

Interventions

OTHER

No Results Yet