Clinical Trials

NCT05880667 | RECRUITING | PHASE1

30 participants

Adaptive Radiation for Abdominopelvic Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-08-01

Completion:

2028-06-01

Conditions

• Neoplasm - Soft Tissue Pelvis Malignant Secondary
• Malignant Neoplasm of Stomach

Interventions

• RADIATION

No Results Yet

NCT05854069 | ACTIVE_NOT_RECRUITING | NA

140 participants

Adapting FAMS to Optimize CGM Use Among Emerging Adults With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-04-30

Completion:

2027-01-31

Conditions

• Type 1 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT05829668 | RECRUITING | NA

20 participants

Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-08-02

Completion:

2026-08-31

Conditions

• Cornelia de Lange Syndrome

Interventions

• BEHAVIORAL

No Results Yet

NCT05784805 | RECRUITING | NA

10 participants

Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-06-24

Completion:

2026-02-28

Conditions

• Seizures

Interventions

• DEVICE

No Results Yet

NCT05670236 | COMPLETED | PHASE4

55 participants

Effect of Knee Pain on Walking Biomechanics

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-01-25

Completion:

2024-07-19

Conditions

• Osteoarthritis, Knee

Interventions

• DRUG

Results Available

NCT05662033 | COMPLETED | PHASE1

93 participants

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy and Chronic Obstructive Pulmonary Disease Participants, to Assess the Relative Oral Bioavailability Between Two Formulations, and the Food Effect on the PK of AZD6793 Compared to Fasting State.

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-12-05

Completion:

2024-10-29

Conditions

• Inflammatory Diseases

Interventions

• DRUG

No Results Yet

NCT05643976 | COMPLETED | NA

43 participants

Investigating KardioPAC Mobile App to Improve Physical Fitness Among Cardiac Rehabilitation Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-01-18

Completion:

2024-06-21

Conditions

• Cardiac Rehabilitation
• Exercise
• Quality of Life

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05597839 | COMPLETED | PHASE1/PHASE2

24 participants

Study of DF9001 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-11-15

Completion:

2025-08-15

Conditions

• Solid Tumor, Adult

Interventions

• DRUG

No Results Yet

NCT05587517 | RECRUITING | PHASE2

172 participants

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-10-11

Completion:

2027-12-11

Conditions

• Grief
• Trauma
• Psychotherapy
• Critical Care

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05586958 | COMPLETED | PHASE3

354 participants

Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-10-25

Completion:

2024-11-04

Conditions

• Gout
• Hyperuricemia
• Gout Flare
• Tophi

Interventions

• DRUG

No Results Yet

NCT05560113 | RECRUITING | NA

66 participants

Disrupting Fear-based Memory Consolidation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-11-28

Completion:

2028-12-31

Conditions

• Post-Traumatic Stress Disorder

Interventions

• OTHER

No Results Yet

NCT05526716 | COMPLETED | PHASE3

1080 participants

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 When Administered Concomitantly With Influenza Vaccine in Adults 50 Years of Age or Older (V116-005, STRIDE-5)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-09-23

Completion:

2023-06-21

Conditions

• Pneumonia, Pneumococcal

Interventions

• BIOLOGICAL

Results Available

NCT05495984 | RECRUITING | NA

15 participants

Neuroplasticity in Maternal Opioid Use Disorder (OUD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-01-01

Completion:

2026-06-30

Conditions

• Opioid Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05490225 | RECRUITING | NA

100 participants

Access Cannulation Trial II

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2025-04-23

Completion:

2027-03-25

Conditions

• Dialysis; Complications
• Vascular Access Complication

Interventions

• DEVICE

No Results Yet

NCT05485376 | RECRUITING | NA

400 participants

Pulmonary Artery Catheter in Cardiogenic Shock Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-08-23

Completion:

2026-09-01

Conditions

• Cardiogenic Shock
• Heart Failure

Interventions

• DEVICE

No Results Yet

NCT05469178 | TERMINATED | PHASE1/PHASE2

26 participants

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-03-03

Completion:

2025-04-03

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT05363111 | RECRUITING | PHASE1

15 participants

Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-11-22

Completion:

2027-03-23

Conditions

• Recurrent Plasma Cell Myeloma
• Refractory Plasma Cell Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT05361382 | ACTIVE_NOT_RECRUITING | PHASE1

822 participants

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-03-02

Completion:

2027-05-31

Conditions

• Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT05330702 | TERMINATED | NA

31 participants

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2023-01-17

Completion:

2024-03-04

Conditions

• Tooth Extraction
• Immediate Implant Placement

Interventions

• DEVICE
• PROCEDURE

Results Available

NCT05274048 | RECRUITING | PHASE1

18 participants

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-06-24

Completion:

2026-06-30

Conditions

• Gastric Cancer
• Gastrointestinal Cancer
• HER2 Gene Mutation

Interventions

• DRUG

No Results Yet

NCT05265429 | RECRUITING

500 participants

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-29

Start Date:

2023-01-01

Completion:

2027-08-01

Conditions

• Non Small Cell Lung Cancer
• Small Cell Lung Carcinoma
• NUT Carcinoma

Interventions

• GENETIC

No Results Yet

NCT05205330 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

107 participants

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-11-23

Completion:

2026-12-31

Conditions

• Refractory Metastatic Colorectal Cancer
• Solid Tumor
• Metastatic Microsatellite-stable Colorectal Cancer
• Mismatch Repair Protein Proficient
• Metastatic GI Cancers
• Gastric Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05183230 | RECRUITING | NA

115 participants

WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-04-22

Completion:

2026-09-30

Conditions

• Suicide, Attempted
• Suicidal Ideation
• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT05169437 | TERMINATED | PHASE2

22 participants

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-03-15

Completion:

2024-08-06

Conditions

• Solid Tumor
• Breast Tumor
• Colon Tumor, Malignant
• Lung Tumor
• Urologic Cancer
• Pancreatic Cancer
• Melanoma
• Metastatic Cancer
• Locally Advanced Solid Tumor
• Esophageal Cancer
• Endometrial Cancer
• Head and Neck Cancer

Interventions

• DRUG

Results Available

NCT05107466 | RECRUITING

100 participants

Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-29

Start Date:

2023-07-28

Completion:

2026-08-01

Conditions

• Sensorineural Hearing Loss
• Hearing Loss

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05029882 | ACTIVE_NOT_RECRUITING | PHASE1

520 participants

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-10-13

Completion:

2027-11-30

Conditions

• Non-Small Cell Lung Cancer
• Advanced Solid Tumors
• Gastroesophageal Adenocarcinoma
• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT04902781 | COMPLETED | PHASE2/PHASE3

47 participants

Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-03-20

Completion:

2023-03-03

Conditions

• Classic Galactosemia

Interventions

• DRUG
• OTHER

No Results Yet

NCT04875195 | COMPLETED | PHASE2

66 participants

A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-06-07

Completion:

2023-12-14

Conditions

• Hodgkin's Lymphoma
• Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Interventions

• BIOLOGICAL

Results Available

NCT04861103 | RECRUITING | PHASE4

12 participants

Anticoagulation Profile in Pregnant Women Treated With Three Times a Day of Low Molecular Weight Heparin (LMWH)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2020-10-01

Completion:

2026-12-31

Conditions

• Pregnancy, High Risk
• Anticoagulants

Interventions

• DRUG

No Results Yet

NCT04821375 | COMPLETED | EARLY_PHASE1

16 participants

Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-12-02

Completion:

2024-05-20

Conditions

• Increased Risk for Development of Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04821141 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-12-14

Completion:

2026-07-31

Conditions

• Risk Reduction
• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04683042 | COMPLETED | PHASE3

459 participants

Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-01-22

Completion:

2025-03-11

Conditions

• Fibromyalgia

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04592874 | COMPLETED | PHASE2

356 participants

A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-01-22

Completion:

2024-08-19

Conditions

• Alzheimer Disease

Interventions

• DRUG

Results Available

NCT04566302 | COMPLETED | NA

16 participants

Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-07-19

Completion:

2021-10-22

Conditions

• Pigmented Lesions
• Pigmented Skin Lesion
• Pigmented Moles
• Skin Lesion

Interventions

• DEVICE

Results Available

NCT04524689 | TERMINATED | PHASE2

57 participants

Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2020-10-26

Completion:

2024-03-12

Conditions

• Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)

Interventions

• DRUG

Results Available

NCT04522739 | COMPLETED | PHASE4

25 participants

Spironolactone Safety in African Americans With Mild Cognitive Impairment and Early Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2022-09-06

Completion:

2025-09-23

Conditions

• Mild Cognitive Impairment
• Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT04511806 | RECRUITING

1050 participants

Childhood Cancer Predisposition Study (CCPS)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-29

Start Date:

2021-04-22

Completion:

2030-10-31

Conditions

• Pediatric Cancer

Interventions

• OTHER

No Results Yet

NCT04420936 | COMPLETED | NA

269 participants

Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-29

Start Date:

2021-09-08

Completion:

2025-06-30

Conditions

• Diabetes
• Weight Loss
• Diet Habit

Interventions

• BEHAVIORAL

No Results Yet

NCT04356443 | TERMINATED

25 participants

Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-29

Start Date:

2020-04-15

Completion:

2020-12-31

Conditions

• Respiratory Failure
• Ventilatory Failure
• COVID-19
• Pneumonia
• ARDS, Human

Interventions

• DEVICE

No Results Yet

NCT04334902 | COMPLETED

221 participants

Evaluation of Clinical Decision Support System-mPDia for Neurodegenerative Parkinsonism Using MRI Images

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-29

Start Date:

2020-03-13

Completion:

2020-06-24

Conditions

• Diagnoses Disease

Interventions

• DEVICE

Results Available