Clinical Trials

NCT06033703 | RECRUITING | PHASE1/PHASE2

48 participants

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2025-01-14

Completion:

2026-09-30

Conditions

• Rhegmatogenous Retinal Detachment
• Proliferative Vitreoretinopathy

Interventions

• DRUG

No Results Yet

NCT05999630 | RECRUITING | PHASE3

100 participants

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-08-21

Completion:

2027-12-31

Conditions

• Nasolacrimal Duct Obstruction
• Thyroid Cancer

Interventions

• DRUG

No Results Yet

NCT05972889 | COMPLETED | NA

334 participants

Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-11-02

Completion:

2025-10-21

Conditions

• Non-Specific Chronic Lower Back Pain

Interventions

• DEVICE

No Results Yet

NCT05954676 | WITHDRAWN | NA

0 participants

Online Peri-operative Education Program for Patients Undergoing Major Head & Neck Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-07-17

Completion:

2027-08-31

Conditions

• Head and Neck Cancer
• Head and Neck Neoplasms

Interventions

• OTHER

No Results Yet

NCT05929339 | COMPLETED | PHASE2

25 participants

Defining a PK and PD Model for Peripheral Analgesia After IV Oxytocin

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-08-17

Completion:

2024-10-02

Conditions

• Acute Pain
• Chronic Pain
• Healthy Volunteer

Interventions

• DRUG

Results Available

NCT05924945 | TERMINATED | NA

13 participants

Impact of Bridge™ Device to Treat Opioid Withdrawal Symptoms

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-06-08

Completion:

2024-08-19

Conditions

• Opioid Use Disorder

Interventions

• DEVICE

Results Available

NCT05918211 | RECRUITING | PHASE3

436 participants

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-10-30

Completion:

2025-10-28

Conditions

• Single Ventricle Heart Disease

Interventions

• DRUG

No Results Yet

NCT05877508 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

Anti-SARS-CoV-2 Monoclonal Antibodies for Long COVID (COVID-19)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-08-01

Completion:

2024-07-29

Conditions

• Long COVID
• Post-Acute Sequela of COVID-19
• Post-Acute COVID-19

Interventions

• DRUG
• OTHER

Results Available

NCT05851300 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2025-10-28

No Results Yet

NCT05809934 | COMPLETED | PHASE2

220 participants

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-03-15

Completion:

2025-07-14

Conditions

• Nonalcoholic Steatohepatitis

Interventions

• DRUG
• OTHER

No Results Yet

NCT05753670 | COMPLETED | PHASE3

179 participants

Effect of Preoperative Tamsulosin on Postoperative Urinary Retention

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-07-01

Completion:

2024-05-02

Conditions

• Postoperative Retention of Urine

Interventions

• DRUG

Results Available

NCT05679154 | COMPLETED | NA

147 participants

Team-Focused Implementation in Child Advocacy Centers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2024-07-31

Completion:

2025-10-08

Conditions

• Mental Health Issue
• Teamwork

Interventions

• BEHAVIORAL

No Results Yet

NCT05601661 | COMPLETED | NA

6 participants

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-06-15

Completion:

2025-08-16

Conditions

• Cervical Spinal Cord Injury

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05590884 | COMPLETED | PHASE2

36 participants

Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-09-21

Completion:

2024-09-30

Conditions

• Central Nervous System Diseases
• Pediatric Disorder
• Body Indication

Interventions

• DRUG

Results Available

NCT05572021 | TERMINATED | NA

6 participants

A Comparison of the Outcomes in Fortiva and Strattice Mesh

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-09-25

Completion:

2025-03-21

Conditions

• Ventral Hernia

Interventions

• DEVICE

Results Available

NCT05478499 | COMPLETED | PHASE4

154 participants

Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-10-06

Completion:

2024-01-11

Conditions

• Psoriasis

Interventions

• DRUG
• OTHER

Results Available

NCT05456685 | ACTIVE_NOT_RECRUITING | PHASE2

125 participants

Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-09-28

Completion:

2026-11-30

Conditions

• High Grade Ovarian Cancer
• Primary Peritoneal Cancer
• Fallopian Tube Cancer

Interventions

• DRUG

No Results Yet

NCT05328167 | COMPLETED | PHASE2

16 participants

Contrast-Enhanced Ultrasound for the Prediction of Bile Duct Cancer Response to Radioembolization Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-12-14

Completion:

2025-07-31

Conditions

• Intrahepatic Cholangiocarcinoma

Interventions

• DRUG
• PROCEDURE

Results Available

NCT05227703 | COMPLETED | PHASE2

391 participants

A Trial of 15 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-07-05

Completion:

2024-08-15

Conditions

• Schizophrenia

Interventions

• DRUG

Results Available

NCT05151640 | COMPLETED

158 participants

INCHANGE - Nintedanib for Changes in Cough and Dyspnea in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-28

Start Date:

2023-02-08

Completion:

2025-09-05

Conditions

• Lung Diseases, Interstitial

Interventions

• DRUG

No Results Yet

NCT05081388 | TERMINATED | PHASE1/PHASE2

25 participants

COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-11-08

Completion:

2022-06-30

Conditions

• SARS-CoV-2

Interventions

• DRUG

Results Available

NCT05026710 | COMPLETED | NA

224 participants

Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-12-02

Completion:

2024-07-01

Conditions

• Renal Stone
• Ureteral Stone

Interventions

• DEVICE

Results Available

NCT04887116 | RECRUITING | EARLY_PHASE1

20 participants

Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2023-10-05

Completion:

2027-01-31

Conditions

• Posttraumatic Stress Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04874415 | COMPLETED | NA

75 participants

Behavioral Economics for Activity Motivation in Adolescents (BEAM)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-11-16

Completion:

2024-10-04

Conditions

• Type 2 Diabetes
• PreDiabetes
• Insulin Resistance
• Polycystic Ovary Syndrome

Interventions

• BEHAVIORAL

Results Available

NCT04849507 | COMPLETED | NA

17 participants

BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-08-01

Completion:

2024-05-24

Conditions

• Infant Feeding Problems, taVNS

Interventions

• DEVICE

Results Available

NCT04802408 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

171 participants

SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-10-01

Completion:

2026-05-30

Conditions

• Covid19
• SARS-CoV Infection

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04700072 | COMPLETED | PHASE1/PHASE2

56 participants

Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-05-03

Completion:

2025-10-17

Conditions

• Melanoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04658472 | COMPLETED | PHASE2

98 participants

Proof-of-concept Study for SAR445088 in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-04-28

Completion:

2025-10-01

Conditions

• Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Interventions

• DRUG

No Results Yet

NCT04546789 | COMPLETED | PHASE1

24 participants

Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2020-09-30

Completion:

2021-05-16

Conditions

• Hepatic Impairment

Interventions

• DRUG

Results Available

NCT04501536 | COMPLETED | NA

59 participants

Determining Optimal Treatment Intensity for Children With Language Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2020-08-10

Completion:

2025-01-09

Conditions

• Language Impairment

Interventions

• BEHAVIORAL

No Results Yet

NCT04443153 | COMPLETED | NA

88 participants

Adapting Diabetes Treatment Expert Systems to Patient in Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2020-09-04

Completion:

2024-09-19

Conditions

• Diabetes Mellitus, Type 1

Interventions

• DEVICE

Results Available

NCT04434807 | RECRUITING | NA

240 participants

Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2020-11-15

Completion:

2027-12-31

Conditions

• Intra Cerebral Hemorrhage
• Stroke

Interventions

• PROCEDURE

No Results Yet

NCT04288427 | RECRUITING | NA

120 participants

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2020-09-25

Completion:

2026-06-30

Conditions

• Benign Prostatic Hyperplasia
• Prostate Hyperplasia
• Prostate Disease
• Prostate Hypertrophy
• Prostate Pain
• Lower Urinary Tract Symptoms
• Urinary Obstruction
• Urinary Tract Disease

Interventions

• DRUG

No Results Yet

NCT04118374 | COMPLETED | NA

14 participants

A Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2021-11-24

Completion:

2024-06-21

Conditions

• Diabetes Mellitus, Type 1

Interventions

• OTHER

Results Available

NCT04016558 | COMPLETED | NA

296 participants

Behavioral Approaches to Reducing Diabetes Distress and Improving Glycemic Control

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2019-09-15

Completion:

2023-02-15

Conditions

• Type 1 Diabetes
• Diabetes Distress

Interventions

• BEHAVIORAL

Results Available

NCT03948984 | COMPLETED | NA

111 participants

Assessing the Impact of LIve Music in the Intensive Care Unit (ICU) to Improve Care for Critically Ill Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2022-05-31

Completion:

2025-02-02

Conditions

• Anxiety
• Pain
• Critical Illness
• Relaxation

Interventions

• BEHAVIORAL

No Results Yet

NCT03804502 | COMPLETED | NA

12 participants

Pilot Study of TearCare System - Long-Term Extension

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2018-12-17

Completion:

2019-05-21

Conditions

• Dry Eye Syndromes

Interventions

• DEVICE

Results Available

NCT03713424 | RECRUITING | PHASE2

30 participants

An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-28

Start Date:

2019-03-26

Completion:

2026-08-31

Conditions

• Tobacco Use Disorder

Interventions

• DRUG

No Results Yet

NCT03667378 | ACTIVE_NOT_RECRUITING

83 participants

Investigating the Impact of Proactive Palliative Care

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-28

Start Date:

2018-09-07

Completion:

2026-09-30

Conditions

• Metastatic Solid Tumor Cancers
• Locally Advanced Solid Tumor Cancers

Interventions

• BEHAVIORAL

No Results Yet

NCT03452774 | RECRUITING

50000 participants

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-28

Start Date:

2018-01-01

Completion:

2038-12-31

Conditions

• Cancer, Metastatic
• Cancer
• Cancer of Pancreas
• Cancer of Liver
• Cancer of Stomach
• Cancer Liver
• Cancer of Rectum
• Cancer of Kidney
• Cancer of Esophagus
• Cancer of Cervix
• Cancer of Colon
• Cancer of Larynx
• Cancer, Lung
• Cancer, Breast
• Cancer, Advanced
• Cancer Prostate
• Cancer of Neck
• Cancer of Skin
• Neuroendocrine Tumors
• Carcinoma
• Mismatch Repair Deficiency
• BRCA Gene Rearrangement
• Non Hodgkin Lymphoma
• Leukemia
• Non Small Cell Lung Cancer
• Cholangiocarcinoma
• Glioblastoma
• Central Nervous System Tumor
• Melanoma
• Urothelial Carcinoma
• Bladder Cancer
• Ovarian Cancer
• Endometrial Cancer
• Testicular Cancer
• Breast Cancer
• COVID
• Myelofibrosis
• Myeloproliferative Neoplasm
• Myeloproliferative Disorders
• Follicular Lymphoma
• Mantle Cell Lymphoma
• Marginal Zone Lymphoma
• Myelodysplastic Syndromes

Interventions

• OTHER

No Results Yet