SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50000
Last updated 2025-10-28
Summary
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical trial enrollment (CTE), as well as the financial impact, and potential outcomes of the intervention.
Conditions
- Cancer, Metastatic
- Cancer
- Cancer of Pancreas
- Cancer of Liver
- Cancer of Stomach
- Cancer Liver
- Cancer of Rectum
- Cancer of Kidney
- Cancer of Esophagus
- Cancer of Cervix
- Cancer of Colon
- Cancer of Larynx
- Cancer, Lung
- Cancer, Breast
- Cancer, Advanced
- Cancer Prostate
- Cancer of Neck
- Cancer of Skin
- Neuroendocrine Tumors
- Carcinoma
- Mismatch Repair Deficiency
- BRCA Gene Rearrangement
- Non Hodgkin Lymphoma
- Leukemia
- Non Small Cell Lung Cancer
- Cholangiocarcinoma
- Glioblastoma
- Central Nervous System Tumor
- Melanoma
- Urothelial Carcinoma
- Bladder Cancer
- Ovarian Cancer
- Endometrial Cancer
- Testicular Cancer
- Breast Cancer
- COVID
- Myelofibrosis
- Myeloproliferative Neoplasm
- Myeloproliferative Disorders
- Follicular Lymphoma
- Mantle Cell Lymphoma
- Marginal Zone Lymphoma
- Myelodysplastic Syndromes
Interventions
- OTHER
-
Clinical Trial Matching
Using a proprietary application programming interface (API) linked to existing electronic health records (EHR) platforms, individual clinical data is extracted, analyzed and matched to a parametric database of existing institutional and non-institutional CT. Machine learning algorithms allow for dynamic matching based on CT allocation and availability for optimized matching.
Sponsors & Collaborators
-
Massive Bio, Inc.
lead INDUSTRY
Principal Investigators
-
Selin Kurnaz, PhD · Massive Bio, Inc.
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-01
- Primary Completion
- 2038-12-31
- Completion
- 2040-06-30
Countries
- United States
- Puerto Rico
Study Locations
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